1,221 research outputs found

    Second Annual Idaho Public Policy Survey

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    The Second Annual Idaho Public Policy Survey was conducted December 3-8, 2016 and surveyed 1000 adults currently living in the state of Idaho. Respondents were asked about their attitudes concerning several key policy issues, including significant focus on revenue and spending, transportation, education, refugees, and energy and climate change. The survey sample was designed to be representative of all regions of the state and was administered on behalf of the School of Public Service by GS Strategy Group, a Boise-based polling firm. Statewide results have a margin of error of +/- 3.1

    The Electron Spectral Function in Two-Dimensional Fractionalized Phases

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    We study the electron spectral function of various zero-temperature spin-charge separated phases in two dimensions. In these phases, the electron is not a fundamental excitation of the system, but rather ``decays'' into a spin-1/2 chargeless fermion (the spinon) and a spinless charge e boson (the chargon). Using low-energy effective theories for the spinons (d-wave pairing plus possible N\'{e}el order), and the chargons (condensed or quantum disordered bosons), we explore three phases of possible relevance to the cuprate superconductors: 1) AF*, a fractionalized antiferromagnet where the spinons are paired into a state with long-ranged N\'{e}el order and the chargons are 1/2-filled and (Mott) insulating, 2) the nodal liquid, a fractionalized insulator where the spinons are d-wave paired and the chargons are uncondensed, and 3) the d-wave superconductor, where the chargons are condensed and the spinons retain a d-wave gap. Working within the Z2Z_2 gauge theory of such fractionalized phases, our results should be valid at scales below the vison gap. However, on a phenomenological level, our results should apply to any spin-charge separated system where the excitations have these low-energy effective forms. Comparison with ARPES data in the undoped, pseudogapped, and superconducting regions is made.Comment: 10 page

    The Acute Effects of the Atypical Dissociative Hallucinogen Salvinorin A on Functional Connectivity in the Human Brain

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    Salvinorin A (SA) is a κ-opioid receptor agonist and atypical dissociative hallucinogen found in Salvia divinorum. Despite the resurgence of hallucinogen studies, the effects of κ-opioid agonists on human brain function are not well-understood. This placebo-controlled, within-subject study used functional magnetic resonance imaging for the first time to explore the effects of inhaled SA on strength, variability, and entropy of functional connectivity (static, dynamic, and entropic functional connectivity, respectively, or sFC, dFC, and eFC). SA tended to decrease within-network sFC but increase between-network sFC, with the most prominent effect being attenuation of the default mode network (DMN) during the first half of a 20-min scan (i.e., during peak effects). SA reduced brainwide dFC but increased brainwide eFC, though only the former effect survived multiple comparison corrections. Finally, using connectome-based classification, most models trained on dFC network interactions could accurately classify the first half of SA scans. In contrast, few models trained on within- or between-network sFC and eFC performed above chance. Notably, models trained on within-DMN sFC and eFC performed better than models trained on other network interactions. This pattern of SA effects on human brain function is strikingly similar to that of other hallucinogens, necessitating studies of direct comparisons

    Ciliary proteins Bbs8 and Ift20 promote planar cell polarity in the cochlea

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    Primary cilia have been implicated in the generation of planar cell polarity (PCP). However, variations in the severity of polarity defects in different cilia mutants, coupled with recent demonstrations of non-cilia-related actions of some cilia genes, make it difficult to determine the basis of these polarity defects. To address this issue, we evaluated PCP defects in cochlea from a selection of mice with mutations in cilia-related genes. Results indicated notable PCP defects, including mis-oriented hair cell stereociliary bundles, in Bbs8 and Ift20 single mutants that are more severe than in other cilia gene knockouts. In addition, deletion of either Bbs8 or Ift20 results in disruptions in asymmetric accumulation of the core PCP molecule Vangl2 in cochlear cells, suggesting a role for Bbs8 and/or Ift20, possibly upstream of core PCP asymmetry. Consistent with this, co-immunoprecipitation experiments indicate direct interactions of Bbs8 and Ift20 with Vangl2. We observed localization of Bbs and Ift proteins to filamentous actin as well as microtubules. This could implicate these molecules in selective trafficking of membrane proteins upstream of cytoskeletal reorganization, and identifies new roles for cilia-related proteins in cochlear PCP

    Two-photon Lithography for 3D Magnetic Nanostructure Fabrication

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    Ferromagnetic materials have been utilised as recording media within data storage devices for many decades. Confinement of the material to a two dimensional plane is a significant bottleneck in achieving ultra-high recording densities and this has led to the proposition of three dimensional (3D) racetrack memories that utilise domain wall propagation along nanowires. However, the fabrication of 3D magnetic nanostructures of complex geometry is highly challenging and not easily achievable with standard lithography techniques. Here, by using a combination of two-photon lithography and electrochemical deposition, we show a new approach to construct 3D magnetic nanostructures of complex geometry. The magnetic properties are found to be intimately related to the 3D geometry of the structure and magnetic imaging experiments provide evidence of domain wall pinning at a 3D nanostructured junction
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