The Kaon B-parameter from Quenched Domain-Wall QCD

We present numerical results for the kaon B-parameter, B_K, determined in the quenched approximation of lattice QCD. Our simulations are performed using domain-wall fermions and the renormalization group improved, DBW2 gauge action which combine to give quarks with good chiral symmetry at finite lattice spacing. Operators are renormalized non-perturbatively using the RI/MOM scheme. We study scaling by performing the simulation on two different lattices with a^{-1} = 1.982(30) and 2.914(54) GeV. We combine this quenched scaling study with an earlier calculation of B_K using two flavors of dynamical, domain-wall quarks at a single lattice spacing to obtain B_K(MS,NDR,mu=2GeV)=0.563(21)(39)(30), were the first error is statistical, the second systematic (without quenching errors) and the third estimates the error due to quenching.Comment: 77 pages, 44 figures, to be published in Phys. Rev.

Enhanced chiral logarithms in partially quenched QCD

I discuss the properties of pions in ``partially quenched'' theories, i.e. those in which the valence and sea quark masses, $m_V$ and $m_S$, are different. I point out that for lattice fermions which retain some chiral symmetry on the lattice, e.g. staggered fermions, the leading order prediction of the chiral expansion is that the mass of the pion depends only on $m_V$, and is independent of $m_S$. This surprising result is shown to receive corrections from loop effects which are of relative size $m_S \ln m_V$, and which thus diverge when the valence quark mass vanishes. Using partially quenched chiral perturbation theory, I calculate the full one-loop correction to the mass and decay constant of pions composed of two non-degenerate quarks, and suggest various combinations for which the prediction is independent of the unknown coefficients of the analytic terms in the chiral Lagrangian. These results can also be tested with Wilson fermions if one uses a non-perturbative definition of the quark mass.Comment: 14 pages, 3 figures, uses psfig. Typos in eqs (18)-(20) corrected (alpha_4 is replaced by alpha_4/2

Scaling of Pseudo-Critical Couplings in Two-Flavour QCD

We study the scaling behaviour of the pseudo-critical couplings for the chiral phase transition in two-flavour QCD. We show that all existing results from lattice simulations on lattices with temporal extent $N_\tau = 4$, 6 and 8 can be mapped onto a universal scaling curve. The relevant combination of critical exponents, $\beta\delta$, is consistent with the scaling behaviour expected for a second order phase transition with $O(4)$ exponents. At present, scaling according to the $O(2)$ symmetry group can, however, not be ruled out.Comment: 8 pages, NSF-ITP 93-12

The Spatial String Tension and Dimensional Reduction in QCD

We calculate the spatial string tension in (2+1) flavor QCD with physical strange quark mass and almost physical light quark masses using lattices with temporal extent N_tau=4,6 and 8. We compare our results on the spatial string tension with predictions of dimensionally reduced QCD. This suggests that also in the presence of light dynamical quarks dimensional reduction works well down to temperatures 1.5T_c.Comment: 8 pages ReVTeX, 4 figure

Pharmacokinetic Interactions between the Hormonal Emergency Contraception, Levonorgestrel (Plan B), and Efavirenz

Objectives. Compare the Plan B levonorgestrel (LNG) area under the concentration- time curve (AUC12) prior to and with efavirenz (EFV). Design. Prospective, open-label, single-arm, equivalence study. Methods. Healthy HIV-negative subjects underwent 12 hr intensive pharmacokinetic (PK) sampling following single dose LNG alone and after 14 days of EFV. Geometric means, Geometric Mean Ratios, and 90% confidence intervals (CI) are reported for PK Parameters. T-tests were utilized. Clinical parameters and liver function tests (LFTs) were assessed. Results. 24 women enrolled and 21 completed the study. With EFV, LNG AUC12 was reduced 56% (95% CI: 49%, 62%) from 42.9 to 17.8 ng∗hr/mL, and maximum concentration (Cmax⁡) was reduced 41% (95% CI: 33%, 50%) from 8.4 to 4.6 ng/mL. LNG was well tolerated with no grade 3 or 4 treatment-related toxicities. Conclusions. EFV significantly reduced LNG exposures. Higher LNG doses may be required with EFV. These results reinforce the importance of effective contraception in women taking EFV

The kaon semileptonic form factor in Nf=2+1 domain wall lattice QCD with physical light quark masses

We present the first calculation of the kaon semileptonic form factor with sea and valence quark masses tuned to their physical values in the continuum limit of 2+1 flavour domain wall lattice QCD. We analyse a comprehensive set of simulations at the phenomenologically convenient point of zero momentum transfer in large physical volumes and for two different values of the lattice spacing. Our prediction for the form factor is f+(0)=0.9685(34)(14) where the first error is statistical and the second error systematic. This result can be combined with experimental measurements of K->pi decays for a determination of the CKM-matrix element for which we predict |Vus|=0.2233(5)(9) where the first error is from experiment and the second error from the lattice computation.Comment: 21 pages, 7 figures, 6 table