Association between 5-HTTLPR genotype and <i>NEO Five-Factor Inventory</i> (NEO-FFI). Mean ± SD. P = level of significance.

<p>Association between 5-HTTLPR genotype and <i>NEO Five-Factor Inventory</i> (NEO-FFI). Mean ± SD. P = level of significance.</p

Distribution of answers to the Italian UPSIT test.

<p>Percentage of correct answers to the 40 odorants of the Italian version of the UPSIT smell identification test by the healthy subjects (n = 54).</p

Paths in mediation model.

<p>Paths in mediation model.</p

Association between 5-HTTLPR genotype and Profile of Mood States (POMS). Mean ± SD. P = level of significance.

<p>Association between 5-HTTLPR genotype and Profile of Mood States (POMS). Mean ± SD. P = level of significance.</p

Gene diversity for <i>TMEM16B/ANO2</i>.

<p>Gene diversity calculated in individuals of the 1000 Genomes Project using all the SNPs in the genes (<b>A</b>) or only the missense mutations (<b>B</b>). <i>TMEM16B/ANO2</i> showed the highest gene diversity among the indicated genes both in A (p = 2.2e-16) and in B (p = 0.042).</p

Assessment of the olfactory function with the adapted Italian UPSIT test.

<p>Number of correct answers to the 34 odorants selected for our adapted Italian UPSIT test for the subgroup of healthy subjects (indicated as control, “ctrl”, green, n = 5), or for members of the family homozygous for the 253 kb deletion in chromosome 12 (indicated as “del”, red, n = 4), heterozygous for the 253 kb deletion (indicated as “het”, blue, n = 3), wild type (indicated as “wt”, grey, n = 1).</p

Correlation (Pearson’s r) between and Sport Performance Psychological Inventory (IPPS), Profile of Mood States (POMS) and Neuroticism.

<p>Correlation (Pearson’s r) between and Sport Performance Psychological Inventory (IPPS), Profile of Mood States (POMS) and Neuroticism.</p

Protein-protein interaction network for TMEM16B/ANO2.

<p>Predicted functional partners obtained with the database STRING v9.01 (<a href="http://string-db.org/" target="_blank">http://string-db.org/</a>).</p

Frequencies of the genotypes and alleles of the 5-HTTLPR.

<p>Frequencies of the genotypes and alleles of the 5-HTTLPR.</p

Association between 5-HTTLPR genotype and Sport Performance Psychological Inventory (IPPS-48). Mean ± SD. P = level of significance.

<p>Association between 5-HTTLPR genotype and Sport Performance Psychological Inventory (IPPS-48). Mean ± SD. P = level of significance.</p