Ocular manifestations of Sturge–Weber syndrome: pathogenesis, diagnosis, and management

Sturge-Weber syndrome has been included in the group of phakomatoses that is characterized by hamartomas involving the brain, skin, and eyes. The characteristic facial port-wine stain, involving the first branch of the trigeminal nerve and the embryonic vasculature distribution in this area, leads to several ocular complications of the anterior segment and can involve the eyelids and conjunctiva. The posterior segment of the eyes is also affected with diffuse choroidal hemangiomas. However, the most frequent ocular comorbidity is glaucoma with a prevalence rate ranging from 30%-70%. Glaucoma is related to anterior chamber malformations, high episcleral venous pressure (EVP), and changes in ocular hemodynamics. Glaucoma can be diagnosed at birth, but the disease can also develop during childhood and in adults. The management of glaucoma in Sturge-Weber syndrome patients is particularly challenging because of early onset, frequently associated severe visual field impairment at the time of diagnosis, and unresponsiveness to standard treatment. Several surgical approaches have been proposed, but long-term prognosis for both intraocular pressure control and visual function remains unsatisfactory in these patients. Choroidal hemangiomas may also lead to visual impairment thorough exudative retinal detachment and macular edema. Treatment of exudative hemangioma complications is aimed at destructing the tumor or decreasing tumor leakage

Follow-up study of over three years of patients with uveitis after cataract phacoemulsification: outcomes and complications

Purpose: To evaluate the rate and onset of intraoperative and postoperative complications post-phacoemulsification. Methods: One hundred sixty-two eyes of 145 patients with uveitis who underwent phacoemulsification between 2006 and 2009 were identified through surgical record review. Fifty-nine eyes of 46 patients met the inclusion criteria. Hazard ratio (HR) and Kaplan-Meier survival probability were calculated for each class of uveitis. Results: Macular edema (ME) resulted to be associated to chronic postoperative inflammation (r = 0.6; p = 0.00) and mostly related to patients who presented more than one postoperative relapse/year (r = 0.2; p = 0.02). Fuchs uveitis resulted to be a risk factor for posterior capsule opacification (PCO) (HR 3.36 IC95%1.0-10.5; p = 0.03). Hypotony and elevated intraocular pressure (IOP) were detected in the anterior uveitis group (0.02 EY). Conclusion: The HR to develop ME was significantly related to chronic anterior uveitis. PCO and elevated IOP are

3D Face Reconstruction: the Road to Forensics

3D face reconstruction algorithms from images and videos are applied to many fields, from plastic surgery to the entertainment sector, thanks to their advantageous features. However, when looking at forensic applications, 3D face reconstruction must observe strict requirements that still make its possible role in bringing evidence to a lawsuit unclear. An extensive investigation of the constraints, potential, and limits of its application in forensics is still missing. Shedding some light on this matter is the goal of the present survey, which starts by clarifying the relation between forensic applications and biometrics, with a focus on face recognition. Therefore, it provides an analysis of the achievements of 3D face reconstruction algorithms from surveillance videos and mugshot images and discusses the current obstacles that separate 3D face reconstruction from an active role in forensic applications. Finally, it examines the underlying data sets, with their advantages and limitations, while proposing alternatives that could substitute or complement them.Comment: The manuscript has been accepted for publication in ACM Computing Surveys. arXiv admin note: text overlap with arXiv:2303.1116

3D Face Reconstruction: the Road to Forensics

3D face reconstruction algorithms from images and videos are applied to many fields, from plastic surgery to the entertainment sector, thanks to their advantageous features. However, when looking at forensic applications, 3D face reconstruction must observe strict requirements that still make its possible role in bringing evidence to a lawsuit unclear. An extensive investigation of the constraints, potential, and limits of its application in forensics is still missing. Shedding some light on this matter is the goal of the present survey, which starts by clarifying the relation between forensic applications and biometrics, with a focus on face recognition. Therefore, it provides an analysis of the achievements of 3D face reconstruction algorithms from surveillance videos and mugshot images and discusses the current obstacles that separate 3D face reconstruction from an active role in forensic applications. Finally, it examines the underlying data sets, with their advantages and limitations, while proposing alternatives that could substitute or complement them

3D Face Reconstruction for Forensic Recognition - A Survey

3D face reconstruction algorithms from images and videos are applied to many fields, from plastic surgery to the entertainment sector, thanks to their advantageous features. However, when looking at forensic applications, 3D face reconstruction must observe strict requirements that still make unclear its possible role in bringing evidence to a lawsuit. Shedding some light on this matter is the goal of the present survey, where we start by clarifying the relation between forensic applications and biometrics. To our knowledge, no previous work adopted this relation to make the point on the state of the art. Therefore, we analyzed the achievements of 3D face reconstruction algorithms from surveillance videos and mugshot images and discussed the current obstacles that separate 3D face reconstruction from an active role in forensic applications

Correlation between morphological characteristics of macular edema and visual acuity in young patients with idiopathic intermediate uveitis

Background and Objectives: Macular edema (ME) is a common complication of intermediate uveitis (IU). It is often responsible for a decrease in visual acuity (VA). Three distinct patterns of macular edema have been described in intermediate uveitis, namely, cystoid macular edema (CME), diffuse macular edema (DME), and serous retinal detachment (SRD). The current study aims to describe the characteristics of macular edema in young patients with idiopathic intermediate uveitis and to correlate its features with VA using spectral domain optical coherence tomography (SD-OCT). Materials and Methods: A total of 27 eyes from 18 patients with idiopathic IU complicated by ME were included in this retrospective study. All patients underwent SD-OCT; data were gathered at the onset of ME. Best-corrected VA (BCVA) was correlated with the morphological features of ME. Results: BCVA was negatively correlated with Ellipsoid Zone (EZ) disruption (p = 0.00021), cystoid pattern (p = 0.00021), central subfield thickness (CST) (p < 0.001), and serous retinal detachment (0.037). Conclusions: In ME secondary to idiopathic IU, VA negatively correlates with Ellipsoid Zone disruption and increases in CST. Moreover, vision is influenced by the presence of cysts in the inner nuclear and outer nuclear layers and by the neuroepithelium detachment

Delayed Onset of Bilateral Acute Retinal Necrosis Syndrome: A 46-Year Interval.

Background: Acute retinal necrosis (ARN) syndrome is an uncommon, severe form of retinitis that is caused by the herpes virus family. Bilateral acute retinal necrosis (BARN) at delayed onset is rare. Methods: A retrospective, interventional case is described in a 64-year-old man complaining of blurred vision in the left eye. The patient had a history of presumed ARN in the right eye at the age of 18 years. Results: The reduced visual acuity and the ocular fundus signs lead us to the diagnosis of delayed-onset BARN. Intravenous and intravitreal antiviral therapy, corticosteroid and antiplatelet treatment were administered until recovering final visual acuity. Conclusions: This report represents the longest reported interval of ARN quiescence with eventual bilateral involvement and illustrates the importance of long-term patient follow-up in immunocompetent patients. Abstract Background: Acute retinal necrosis (ARN) syndrome is an uncommon, severe form of retinitis that is caused by the herpes virus family. Bilateral acute retinal necrosis (BARN) at delayed onset is rare. Methods: A retrospective, interventional case is described in a 64-year-old man complaining of blurred vision in the left eye. The patient had a history of presumed ARN in the right eye at the age of 18 years. Results: The reduced visual acuity and the ocular fundus signs lead us to the diagnosis of delayed-onset BARN. Intravenous and intravitreal antiviral therapy, corticosteroid and antiplatelet treatment were administered until recovering final visual acuity. Conclusions: This report represents the longest reported interval of ARN quiescence with eventual bilateral involvement and illustrates the importance of long-term patient follow-up in immunocompetent patients