Additional file 1: of Stages of behavioural change after direct-to-consumer disease risk profiling: study protocol of two integrated controlled pragmatic trials

SPIRIT 2013 checklist: recommended items to address in a clinical trial protocol and related documents. (DOC 123 kb

Additional file 1: Table S1. of Blood pressure in young adulthood and residential greenness in the early-life environment of twins

Pearson correlation coefficient between greenness in early-life and adult life. Table S2. Collinearity diagnosis. Table S3. Estimated difference in night systolic blood pressure (mm Hg) with land-use indicators at birth in all buffer sizes in twins who moved since birth. Figure S1. Ambulatory blood pressure (mm Hg) in association with residential greenness exposure with no adjustment for exposure in adulthood/early-life in twins who moved during life. Figure S2. Ambulatory blood pressure (mm Hg) in association with residential area. Figure S3. Ambulatory blood pressure (mm Hg) in association with industrial area. (DOCX 872 kb

MOESM1 of Variation in extracellular matrix genes is associated with weight regain after weight loss in a sex-specific manner

Supplementary material 1 (PDF 158 kb

Additional file 2: Table S1. of UroMark—a urinary biomarker assay for the detection of bladder cancer

RainDance target primers. (XLSX 13 kb

Additional file 4: Table S3. of UroMark—a urinary biomarker assay for the detection of bladder cancer

RainDance custom sequencing primers. (XLSX 8 kb

Additional file 5: Figure S1. of UroMark—a urinary biomarker assay for the detection of bladder cancer

A) MDS plot of 150 UroMark loci panel, tumour = red, normal = blue, B) ROC for cross validation accuracy of 150 loci UroMark assay. Figure S2. A) MDS plot of 150 UroMark loci panel in 179 sample validation cohort, High grade = red, low grade = green, normal = blue, B) ROC for cross validation accuracy of 150 loci UroMark assay in the 179 sample validation cohort. Figure S3. A) Boxplots of methylation values for top 10 performing markers in the primary tissue training cohort. B) Boxplots of methylation values for top 10 performing markers in the in urine samples validation cohorts (normal – confirmed no tumour, tumour - histological confirmation of TCC). Figure S4. A) Boxplots of methylation values for top 10 performing markers in the primary tissue training cohort. B) Boxplots of methylation values for top 10 performing markers in the in urine samples validation cohorts (normal – confirmed no tumour, tumour histological confirmation of TCC). (PDF 164 kb