5 research outputs found

    The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline

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    Purpose: High flow nasal cannula (HFNC) is a relatively recent respiratory support technique which delivers high flow, heated and humidified controlled concentration of oxygen via the nasal route. Recently, its use has increased for a variety of clinical indications. To guide clinical practice, we developed evidence-based recommendations regarding use of HFNC in various clinical settings. Methods: We formed a guideline panel composed of clinicians, methodologists and experts in respiratory medicine. Using GRADE, the panel developed recommendations for four actionable questions. Results: The guideline panel made a strong recommendation for HFNC in hypoxemic respiratory failure compared to conventional oxygen therapy (COT) (moderate certainty), a conditional recommendation for HFNC following extubation (moderate certainty), no recommendation regarding HFNC in the peri-intubation period (moderate certainty), and a conditional recommendation for postoperative HFNC in high risk and/or obese patients following cardiac or thoracic surgery (moderate certainty). Conclusions: This clinical practice guideline synthesizes current best-evidence into four recommendations for HFNC use in patients with hypoxemic respiratory failure, following extubation, in the peri-intubation period, and postoperatively for bedside clinicians

    Identification of beauty and charm quark jets at LHCb

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    Identification of jets originating from beauty and charm quarks is important for measuring Standard Model processes and for searching for new physics. The performance of algorithms developed to select b- and c-quark jets is measured using data recorded by LHCb from proton-proton collisions at root s = 7TeV in 2011 and at root s = 8TeV in 2012. The efficiency for identifying a b (c) jet is about 65%(25%) with a probability for misidentifying a light-parton jet of 0.3% for jets with transverse momentum pT > 20GeV and pseudorapidity 2 : 2 < eta < 4.2. The dependence of the performance on the pT and eta of the jet is also measured

    Observation of the B0→ρ0ρ0 decay from an amplitude analysis of B0→(π+π−)(π+π−) decays

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    Proton-proton collision data recorded in 2011 and 2012 by the LHCb experiment, corresponding to an integrated luminosity of 3.0 fb(-1), are analysed to search for the charmless B-0 -> rho(0)rho(0) decay. More than 600 B-0 -> (pi(+)pi(-))(pi(+)pi(-)) signal decays are selected and used to perform an amplitude, analysis, under the assumption of no CP violation in the decay, from which the B-0 -> rho(0)rho(0) decay is observed for the first time with 7.1 standard deviations significance. The fraction of B-0 -> rho(0)rho(0) decays yielding a longitudinally polarised final state is measured to be f(L) = 0.745(-0.058)(+0.048)(stat) +/- 0.034(syst). The B-0 -> rho(0)rho(0) branching fraction, using the B-0 -> phi K*(892)(0) decay as reference, is also reported as B(B-0 -> rho(0)rho(0)) = (0.94 +/- 0.17(stat) +/- 0.09(syst) +/- 0.06(BF)) x 10(-6). (C) 2015 CERN for the benefit of the LHCb Collaboration. Published by Elsevier B.V. This is an open access article under the CC BY licens

    Identification of beauty and charm quark jets at LHCb

    No full text
    Identification of jets originating from beauty and charm quarks is important for measuring Standard Model processes and for searching for new physics. The performance of algorithms developed to select b- and c-quark jets is measured using data recorded by LHCb from proton-proton collisions at √s = 7 TeV in 2011 and at √s = 8 TeV in 2012. The efficiency for identifying a b(c) jet is about 65%(25%) with a probability for misidentifying a light-parton jet of 0.3% for jets with transverse momentum p(T) > 20GeV and pseudorapidity 2.2 < η < 4.2. The dependence of the performance on the p(T) and η of the jet is also measured

    B flavour tagging using charm decays at the LHCb experiment

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    An algorithm is described for tagging the flavour content at production of neutral B mesons in the LHCb experiment. The algorithm exploits the correlation of the flavour of a B meson with the charge of a reconstructed secondary charm hadron from the decay of the other b hadron produced in the proton-proton collision. Charm hadron candidates are identified in a number of fully or partially reconstructed Cabibbo-favoured decay modes. The algorithm is calibrated on the self-tagged decay modes B+ -> J/psi K+ and B-0 -> J/psi K*(0) using 3.0fb(-1) of data collected by the LHCb experiment at pp centre-of-mass energies of 7TeV and 8TeV. Its tagging power on these samples of B -> J/psi X decays is (0.30 +/- 0.01 +/- 0.01) %
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