26 research outputs found
Age-associated differences in triceps surae muscle composition and strength â an MRI-based cross-sectional comparison of contractile, adipose and connective tissue
Long-term T2 and Qualitative MRI Morphology After First-Generation Knee Autologous Chondrocyte Implantation
Glycosaminoglycan chemical exchange saturation transfer at 3T MRI in asymptomatic knee joints
Diffusion tensor imaging of the anterior cruciate ligament following primary repair with internal bracing: A longitudinal study
Rapid Knee MRI Acquisition and Analysis Techniques for Imaging Osteoarthritis
Osteoarthritis (OA) of the knee is a major source of disability that has no known treatment or cure. Morphological and compositional MRI is commonly used for assessing the bone and soft tissues in the knee to enhance the understanding of OA pathophysiology. However, it is challenging to extend these imaging methods and their subsequent analysis techniques to study large population cohorts due to slow and inefficient imaging acquisition and postprocessing tools. This can create a bottle-neck in assessing early OA changes and evaluating the responses of novel therapeutics. The purpose of this review article is to highlight recent developments in tools for enhancing the efficiency of knee MRI methods useful to study OA. Advances in efficient MRI data acquisition and reconstruction tools for morphological and compositional imaging, efficient automated image analysis tools, and hardware improvements to further drive efficient imaging are discussed in this review. For each topic, we discuss the current challenges as well as potential future opportunities to alleviate these challenges