Comparison of the DRB1 * 04 allelic variants of the study and control populations.

The allele variants with significant p values are in bold.</p

Fig 2 -

A) Comparison between the haplotypes of the T1DM population and those of the control population. B) Comparison of the DRB1 * 04 allelic variant of the study and control populations.</p

Comparison of haplotypes between the population with T1DM and healthy controls.

Comparison of haplotypes between the population with T1DM and healthy controls.</p

Flow chart of performed HLA class II typing in T1DM population.

In white the routinary steps based on “Eurospital Diabegen I and II step”; in gray the added specifc study-steps based on PCR SSP (Sequence Specific Primers) technique.</p

Autoantibodies anti-IA2, anti-IAA e anti-GAD frequencies: Age distribution.

Autoantibodies anti-IA2, anti-IAA e anti-GAD frequencies: Age distribution.</p

All demographic, clinical and serological details for 163 subjects affected by T1DM with HLA high-resolution.

(DOCX)</p