Threshold criterion for functional regions of interest.

<p>Effect of threshold criterion using the functional region of interest (fROI) method on the global inhomogeneity (GI) index (A) and on the coefficient of variation (CV) (B) in ARDS and control patients. * p < 0.05 for comparison between ARDS and control patients.</p

Basic Patient characteristics.

<p>Basic Patient characteristics.</p

Area under the receiver operating characteristics curve (AUC), 95% confidence interval for AUC and p-value for different threshold criteria using the lung area estimation method (LAEM) and the coefficient of variation (CV).

<p>Comparison between patients suffering from acute respiratory distress syndrome (ARDS) and control patients without pulmonary pathologies.</p

Area under the receiver operating characteristics curve (AUC), 95% confidence interval for AUC and p-value for different threshold criteria using a functional region of interest with the heart region removed (fROI-heart) and the coefficient of variation (CV).

<p>Comparison between patients suffering from acute respiratory distress syndrome (ARDS) and control patients without pulmonary pathologies.</p

Discrimination between ARDS and control using the lung area estimation method.

<p>(A) Receiver operating characteristics (ROC) curve for discrimination between ARDS and control subjects using the global inhomogeneity index and the lung area estimation method with a criterion of 50% of the maximum impedance change. (B) ROC curve for the same comparison using the coefficient of variation.</p

Creating an x-symmetrical region of interest (ROI) using the lung area estimation method (LAEM) in a patient with acute respiratory distress syndrome.

<p>From the raw image (A) a conventional functional ROI is created, in this example using a threshold criterion of 50% of the maximum impedance difference (B). In the next step (C), the ROI is mirrored by means of a Boolean “OR”-operation. The cardiac area is identified in the frequency domain (D, E) and subsequently subtracted from the x-symmetrical ROI to obtain the final LAEM ROI (F).</p

Additional file 2: of Influence of pathogen and focus of infection on procalcitonin values in sepsis patients with bacteremia or candidemia

Figure S1. P–P plots of PCT and logPCT. Figure S2. AUC plots for ROC analyses. Tables S1 and S2. Regression models limited to cases with blood cultures taken before start of antimicrobial therapy (DOC 215 kb

Area under the receiver operating characteristics curve (AUC), 95% confidence interval for AUC and p-value for different threshold criteria using the lung area estimation method (LAEM) and the global inhomogeneity index (GI).

<p>Comparison between patients suffering from acute respiratory distress syndrome (ARDS) and control patients without pulmonary pathologies.</p

Area under the receiver operating characteristics curve (AUC), 95% confidence interval for AUC and p-value for different threshold criteria using functional region of interest (fROI) and the coefficient of variation (CV).

<p>Comparison between patients suffering from acute respiratory distress syndrome (ARDS) and control patients without pulmonary pathologies.</p

Area under the receiver operating characteristics curve (AUC), 95% confidence interval for AUC and p-value for different threshold criteria using functional region of interest (fROI) and the global inhomogeneity (GI) index.

<p>Comparison between patients suffering from acute respiratory distress syndrome (ARDS) and control patients without pulmonary pathologies.</p