Additional file 1: of A mixed methods study to evaluate the feasibility of using the Adolescent Diabetes Needs Assessment Tool App in paediatric diabetes care in preparation for a longitudinal cohort study

Ethics. (PDF 169 kb

Additional file 2: of A mixed methods study to evaluate the feasibility of using the Adolescent Diabetes Needs Assessment Tool App in paediatric diabetes care in preparation for a longitudinal cohort study

Recruitment. (DOCX 14 kb

Comparison of costs for growth hormone doses calculated using total body weight (TBW), ideal body weight (IBW) and lean body weight (LBW).

<p>Comparison of costs for growth hormone doses calculated using total body weight (TBW), ideal body weight (IBW) and lean body weight (LBW).</p

Comparison of the baseline height SDS and IGF-1 SDS scores for the children in each BMI-SDS cohort for both the entire group and GHD subgroup.

<p>Comparison of the baseline height SDS and IGF-1 SDS scores for the children in each BMI-SDS cohort for both the entire group and GHD subgroup.</p

Children's demographic characteristics, medicine type and ADR information.

1<p>Age reported in year groups: 0–2; 3–5; 6–11; 12 years and over.</p>2<p>Calculated using Lower Super Output Area (LSOA) 2007 ranked score data, whereby lower scores indicate greater deprivation (data for families outside England are not reported due to incompatibility between IMD scoring systems within UK).</p>3<p>Severity scores were assessed using the Hartwig scale <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0046022#pone.0046022-Hartwig1" target="_blank">[84]</a> where 1 = No change in treatment with suspected drug; 2 = Drug dosing or frequency changed, without antidote or treatment for exhibited symptoms; 3 = Required treatment, or drug administration discontinued; 4 = Resulted in patient transfer to higher level of care; 5 = Caused permanent harm to patient or significant haemodynamic instability; 6 = Directly or indirectly resulted in patient death.</p

Breakdown of percentage agreement and extreme disagreement between specialties.

<p>Breakdown of percentage agreement and extreme disagreement between specialties.</p

Flow chart of the development of the Liverpool ADR avoidability assesmsent tool.

<p>Flow chart of the development of the Liverpool ADR avoidability assesmsent tool.</p

The Liverpool ADR avoidability assessment tool (LAAT).

<p>The Liverpool ADR avoidability assessment tool (LAAT).</p

Hallas and the modified Hallas scale.

<p>Hallas and the modified Hallas scale.</p

Parent co-Designed Drug Information for parents and Guardians Taking Neonates home (PADDINGToN) a mixed method approach to defining and evaluating information resources

Background A study of premature babies, less than 32 weeks gestation, found that the median number of medicines per patient at discharge was 2.5 (range 2 to 7), with 28% of babies discharged on more than 3 medicines (1). Medication administration to infants can cause anxiety and concern for parents/carers who worry about making mistakes. A systematic review of carers for all ages has estimated the administration error rate at home to be between 2 and 33% (2) while a rate of 66.3% was recorded in medication administered to premature infants where parents were responsible for administration (3). It has also been reported that up to 90% of carers will administer a medicine incorrectly at some point (2).The aim of this study is to work with healthcare professionals (HCPs) and parents/carers to co-design resources aimed at improving medication safety and reducing parental anxiety for those giving medications to neonates at home.Methods Work Package 1: Project management and co-ordination phase: preparation of protocols and survey material and ethics approval applications.Work Package 2: Stakeholder engagement phase, e-surveys and focus groups: An electronic-survey (e-survey) will be developed by a multi-disciplinary study management group (SMG).This will be circulated to HCPs involved in the care of neonates and parents/carers whose babies had recently been discharged from hospital. A small number of parents/carers will be invited to take part in focus groups.Work Package 3: Co-design of resources and quantitative evaluation: Parents/carers willing to co-design educational and information resources to support safe administration of medicines to neonates following discharge will be recruited. A quantitative evaluation of the effect of the resource will be conducted with a new group of caregivers to measure specific outcome(s).Discussion This study aims to co-develop, with healthcare professionals (HCPs) and parents/carers, resources aimed at improving medication safety and reducing parental anxiety for those giving medications to neonates at home. Co-development of resources with HCPs and parents, ensures that the project outcomes are relevant and useful, leading to a reduction in parental anxiety.Trial registration ISRCTN registry Ref 17332620</p