103 research outputs found
Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules
Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A. thanks the Northern Research Partnership (www.northscotland-research.ac.uk/) and Pharmaness (www.pharmaness.it) for co-funding a PhD studentship.Peer reviewedPostprin
Improved synthesis of the hypoxia probe 5-deutero-5-fluoro-5-deoxy-azomycin arabinoside (FAZA) as a model process for tritium radiolabeling
Peer reviewedPublisher PD
Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status
Open Access via Springer Compact Agreement Acknowledgements We are very grateful to Prof. Calderwood (Yale University, USA) for providing the THD DNA construct, Dr. Massimiliano Baldassarre (University of Aberdeen) for useful discussions on integrin regulation and Charlie Taylor for helping to optimise the THD transfection experiments. We thank the NHS Grampian Endowment Fund for funding this research and CRANES and the Roland Sutton Academic Trust for financial support for AA.Peer reviewedPublisher PD
KEMTUB012-NI2, a novel potent tubulysin analog that selectively targets hypoxic cancer cells and is potentiated by cytochrome p450 reductase downregulation
Peer reviewedPublisher PD
Synthesis and radio-synthesis of prospective 2-nitroimidazole hypoxia PET tracers via thiazolidine ligation with 5-fluorodeoxyribose (FDR)
Funding Information M.M. gratefully acknowledges SULSA (http://www.sulsa.ac.uk/) for a PhD studentship. Acknowledgment Mr Federico Toson is gratefully acknowledged for conducting preliminary experiments. Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591863.Peer reviewedPublisher PD
Design and synthesis of an RGD peptidomimetic-paclitaxel conjugate targeting αvβ3 integrin for tumour-directed drug delivery
We thank the Development Trust, University of Aberdeen, for funding a fellowship to M.P. and a studentship to A.A. Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1590898.Peer reviewedPostprin
Enzymatic radiosynthesis of a 18F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)
We thank the Engineering and Physical Sciences Research Council, UK, for a research grant (EP/M01262X/1).Peer reviewedPostprin
Synthesis of the fungal metabolite YWA1 and related constructs as tools to study MelLec-mediated immune response to Aspergillus infections
Funding Sources Funding was provided by the Wellcome Trust (102705, 097377), the Medical Research Council Centre for Medical Mycology and the University of Aberdeen (MR/N006364/1). ACKNOWLEDGMENT We thank Ian Fraser Flow Cytometry and Microscopy and Histology facilities, University of Aberdeen.Peer reviewedPostprin
NGR Tumor-Homing Peptides : Structural Requirements for Effective APN (CD13) Targeting
Acknowledgements We thank The Development Trust, University of Aberdeen, for financial support and a fellowship to M.P.Peer reviewedPublisher PD
Hypoxia PET/CT and Colorectal Cancer : A Case Report
Funding: Funding for the pilot study was provided by the Colorectal Study Fund, a NHSG endowment fund number: NER 11482.Peer reviewedPublisher PD
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