103 research outputs found

    Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules

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    Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A. thanks the Northern Research Partnership (www.northscotland-research.ac.uk/) and Pharmaness (www.pharmaness.it) for co-funding a PhD studentship.Peer reviewedPostprin

    Binding of αvβ3 Integrin-Specific Radiotracers Is Modulated by Both Integrin Expression Level and Activation Status

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    Open Access via Springer Compact Agreement Acknowledgements We are very grateful to Prof. Calderwood (Yale University, USA) for providing the THD DNA construct, Dr. Massimiliano Baldassarre (University of Aberdeen) for useful discussions on integrin regulation and Charlie Taylor for helping to optimise the THD transfection experiments. We thank the NHS Grampian Endowment Fund for funding this research and CRANES and the Roland Sutton Academic Trust for financial support for AA.Peer reviewedPublisher PD

    Synthesis and radio-synthesis of prospective 2-nitroimidazole hypoxia PET tracers via thiazolidine ligation with 5-fluorodeoxyribose (FDR)

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    Funding Information M.M. gratefully acknowledges SULSA (http://www.sulsa.ac.uk/) for a PhD studentship. Acknowledgment Mr Federico Toson is gratefully acknowledged for conducting preliminary experiments. Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591863.Peer reviewedPublisher PD

    Design and synthesis of an RGD peptidomimetic-paclitaxel conjugate targeting αvβ3 integrin for tumour-directed drug delivery

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    We thank the Development Trust, University of Aberdeen, for funding a fellowship to M.P. and a studentship to A.A. Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1590898.Peer reviewedPostprin

    Enzymatic radiosynthesis of a 18F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)

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    We thank the Engineering and Physical Sciences Research Council, UK, for a research grant (EP/M01262X/1).Peer reviewedPostprin

    Synthesis of the fungal metabolite YWA1 and related constructs as tools to study MelLec-mediated immune response to Aspergillus infections

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    Funding Sources Funding was provided by the Wellcome Trust (102705, 097377), the Medical Research Council Centre for Medical Mycology and the University of Aberdeen (MR/N006364/1). ACKNOWLEDGMENT We thank Ian Fraser Flow Cytometry and Microscopy and Histology facilities, University of Aberdeen.Peer reviewedPostprin

    NGR Tumor-Homing Peptides : Structural Requirements for Effective APN (CD13) Targeting

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    Acknowledgements We thank The Development Trust, University of Aberdeen, for financial support and a fellowship to M.P.Peer reviewedPublisher PD

    Hypoxia PET/CT and Colorectal Cancer : A Case Report

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    Funding: Funding for the pilot study was provided by the Colorectal Study Fund, a NHSG endowment fund number: NER 11482.Peer reviewedPublisher PD
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