149 research outputs found
Are Private Remedies in Domestic Courts Essential for International Trade Agreements to Perform Constitutional Functions with Respect to Sub-Federal Governments?
The term constitutionalism is increasingly discussed in the context of international trade agreements. A prominent example is Professor Petersmann\u27s writings on the constitutional functions that trade agree- ments could serve by limiting governmental discretion to take welfare- reducing protectionist measures against the long-term interests of a nation and contrary to individual economic liberty.\u27 The absence of such protectionist constraints and foreign trade rights in domestic con- stitutions can be mitigated (and already is mitigated somewhat) through the development of international trade rules and institutions
Are Private Remedies in Domestic Courts Essential for International Trade Agreements to Perform Constitutional Functions with Respect to Sub-Federal Governments?
The term constitutionalism is increasingly discussed in the context of international trade agreements. A prominent example is Professor Petersmann\u27s writings on the constitutional functions that trade agree- ments could serve by limiting governmental discretion to take welfare- reducing protectionist measures against the long-term interests of a nation and contrary to individual economic liberty.\u27 The absence of such protectionist constraints and foreign trade rights in domestic con- stitutions can be mitigated (and already is mitigated somewhat) through the development of international trade rules and institutions
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Sevoflurane Preconditioning Limits Intracellular/Mitochondrial Ca2+ in Ischemic Newborn Myocardium
UnlabelledSevoflurane preconditioning (SPC) in adult hearts reduces myocardial ischemia/reperfusion (I/R) injury, an effect that may be mediated by reductions in intracellular Ca(2+) ([Ca(2+)](i)) and/or mitochondrial Ca(2+) ([Ca(2+)](m)) accumulation during ischemia and reperfusion. Because the physiology, pharmacology, and metabolic responses of the newborn differ from adults, we tested the hypothesis that SPC protects newborn myocardium by limiting [Ca(2+)](i) and [Ca(2+)](m) by a K(ATP) channel-dependent mechanism. Fluorescence spectrofluorometry and nuclear magnetic resonance spectroscopy were used to measure [Ca(2+)](i), [Ca(2+)](m), and adenosine triphosphate (ATP) in 4- to 7-day-old Langendorff-perfused rabbit hearts. Three experimental groups were used to study the effect of SPC on [Ca(2+)](m)/[Ca(2+)](i), ATP, as well as hemodynamics and ischemic injury. The role of mitochondrial K(ATP) channels was assessed by exposing the SPC hearts to the mitochondrial K(ATP) channel blocker 5-hydroxydecanoic acid. Our results show that SPC significantly decreased [Ca(2+)](i) and [Ca(2+)](m) during I/R, as well as decreased creatine kinase release during reperfusion and resulted in higher ATP. 5-Hydroxydecanoic acid abolished the effect of SPC on [Ca(2+)], hemodynamics, ATP, and creatine kinase release. In conclusion, decreased [Ca(2+)](i) and [Ca(2+)](m) observed with SPC is associated with greater ATP recovery as well as diminished cell injury. Mitochondrial K(ATP) channel blockade attenuates the SPC effect during I/R, suggesting that these channels are involved in the protective effects of SPC in the newborn.ImplicationsThe results of this study support the hypothesis that sevoflurane preconditioning protects newborn hearts from calcium overload and ischemic injury via a mechanism dependent on mitochondrial KATP channels
SPACE, CYBER, AND TELECOMMUNICATIONS LAW: 2019-2020 Annual Report
In assembling this Annual Report we appreciated the opportunity to review major accomplishments and growth of the Space, Cyber, and Telecommunications Law (SCTL) program during the 2019-2020 academic year. Of course, this was a year like no other as we responded to an unfolding global pandemic. We are proud of what we accomplished prior to that and of our response in the face of that sudden change. For readers unfamiliar with the program, the SCTL program was established in 2007 largely in response to interest by the U.S. Air Force in establishing a U.S. based program in space law to which it could send Judge Advocate General (JAG) officers. At the time it was established, the law school recognized the narrowness of the field and decided to focus the program more broadly on space law as the thencurrent domain of interest to the Department of Defense (DoD), on cyberlaw as the likely next domain of interest both to DoD and the nation generally, and on telecommunications as a common foundation necessary to both. We continue to focus on service to the state of Nebraska, taking on issues such as the rural digital divide and agricultural access to broadband, and our global community. We engage with international organizations and colleagues on challenges our society faces in space and online. The program faculty (and students) are active researchers, and the program organizes various events, including an annual conference in Washington, D.C. (one of the largest regular events focusing on space law), an annual conference in conjunction with USSTRATCOM (on DoD operational issues relating to space, cyber, and related issues), and an annual conference in Lincoln focusing on telecommunications and cyber issues as they impact the region. We appreciate continued support from the state of Nebraska, the University of Nebraska, our board members, and many of our friends and colleagues across the world
Reflections on the 30th Anniversary of the IEEE Symposium on Security and Privacy
Peter G. Neumann, Matt Bishop, Sean Peisert, and Marv Schaefer, "Reflections on the 30th Anniversary of the IEEE Symposium on Security and Privacy," Proceedings of the 31st IEEE Symposium on Security and Privacy, pp. 3–13, Oakland/Berkeley, CA, May 16–19, 2010
The SAMI Galaxy Survey: Revising the Fraction of Slow Rotators in IFS Galaxy Surveys
The fraction of galaxies supported by internal rotation compared to galaxies
stabilized by internal pressure provides a strong constraint on galaxy
formation models. In integral field spectroscopy surveys, this fraction is
biased because survey instruments typically only trace the inner parts of the
most massive galaxies. We present aperture corrections for the two most widely
used stellar kinematic quantities and . Our
demonstration involves integral field data from the SAMI Galaxy Survey and the
ATLAS Survey. We find a tight relation for both and
when measured in different apertures that can be used as a linear
transformation as a function of radius, i.e., a first-order aperture
correction. We find that and radial growth curves are
well approximated by second order polynomials. By only fitting the inner
profile (0.5), we successfully recover the profile out to one
if a constraint between the linear and quadratic parameter in the
fit is applied. However, the aperture corrections for and
derived by extrapolating the profiles perform as well as applying
a first-order correction. With our aperture-corrected
measurements, we find that the fraction of slow rotating galaxies increases
with stellar mass. For galaxies with 11, the fraction
of slow rotators is percent, but is underestimated if galaxies
without coverage beyond one are not included in the sample
( percent). With measurements out to the largest aperture radius
the slow rotator fraction is similar as compared to using aperture corrected
values ( percent). Thus, aperture effects can significantly bias
stellar kinematic IFS studies, but this bias can now be removed with the method
outlined here.Comment: Accepted for Publication in the Monthly Notices of the Royal
Astronomical Society. 16 pages and 11 figures. The key figures of the paper
are: 1, 4, 9, and 1
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