Placental Transfer of 18F-2-Deoxy-2-Fluoroglucose and 14C-4-Iodoantipyrine in Hypoxic Rats

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Two-scale competition in phase separation with shear

The behavior of a phase separating binary mixture in uniform shear flow is investigated by numerical simulations and in a renormalization group (RG) approach. Results show the simultaneous existence of domains of two characteristic scales. Stretching and cooperative ruptures of the network produce a rich interplay where the recurrent prevalence of thick and thin domains determines log-time periodic oscillations. A power law growth $R(t) \sim t^{\alpha}$ of the average domain size, with $\alpha =4/3$ and $\alpha = 1/3$ in the flow and shear direction respectively, is shown to be obeyed.Comment: 5 Revtex pages, 4 figure

Evaluation of infiltrative growth pattern in squamous cell carcinoma of the tongue: Comparison with Yamamoto–Kohama classification

博士（歯学）・第２１１２号（甲　第1325号）・平成２７年３月３１日学術雑誌投稿済み論文による学位審査のため、本文(出版社版)登録不可。よって、著者最終稿を要約として登録

The effect of fibroblast growth factor 7 on human dental pulp stem cells for differentiation to AQP5-positive and αSMA-positive cells in vitro and in vivo

OBJECTIVES: Transplantation of stem cells into wounds has become popular in regeneration therapies. As stem cells for transplantation, human dental pulp stem cells (hDPSCs) are known to be pluripotent cells that are relatively easy to collect from the pulp of deciduous or wisdom teeth. The purpose of this study was to investigate whether hDPSCs treated with fibroblast growth factor 7 (FGF7) would contribute to the regeneration of wounded rat submandibular glands (SMGs). MATERIALS AND METHODS: In in vitro studies, hDPSCs were treated with or without FGF7 and mRNA expression levels were examined at days 3, 7 and 14 using qRT‐PCR. The target genes analyzed were BMI1 as an undifferentiated marker, AQP5 as an acinar cell marker, CK19 as a ductal epithelial cell marker, αSMA as a myoepithelial cell marker and VIMENTIN as a fibroblast marker. In in vivo studies, hDPSCs treated with or without FGF7 for 14 days were mixed with type I collagen gels and were transplanted into wounded rat SMGs. Hematoxylin–Eosin and immunohistochemical staining were performed at days 3 and 7, and the numbers of positive cells were counted. The primary antibodies used were against BMI1, AQP5, αSMA, PanCK and VIMENTIN. RESULTS: In the in vitro studies, mRNA levels of BMI1 were decreased and αSMA were increased at days 3, 7 and 14, while AQP5 was increased at day 14 in the FGF7 group. In the in vivo studies, the proliferation of hDPSCs and cell islands was observed at day 7 in the FGF7 group. Few BMI1‐positive cells were observed, while numbers of AQP5‐positive and αSMA‐positive cells were increased at days 3 and 7 in the FGF7 group. Moreover, cell islands were AQP5‐positive. CONCLUSION: These results suggest that FGF7‐treated hDPSCs differentiate into AQP5‐positive and αSMA‐positive cells. Moreover, AQP5‐positive cell aggregations were formed

Phase separating binary fluids under oscillatory shear

We apply lattice Boltzmann methods to study the segregation of binary fluid mixtures under oscillatory shear flow in two dimensions. The algorithm allows to simulate systems whose dynamics is described by the Navier-Stokes and the convection-diffusion equations. The interplay between several time scales produces a rich and complex phenomenology. We investigate the effects of different oscillation frequencies and viscosities on the morphology of the phase separating domains. We find that at high frequencies the evolution is almost isotropic with growth exponents 2/3 and 1/3 in the inertial (low viscosity) and diffusive (high viscosity) regimes, respectively. When the period of the applied shear flow becomes of the same order of the relaxation time $T_R$ of the shear velocity profile, anisotropic effects are clearly observable. In correspondence with non-linear patterns for the velocity profiles, we find configurations where lamellar order close to the walls coexists with isotropic domains in the middle of the system. For particular values of frequency and viscosity it can also happen that the convective effects induced by the oscillations cause an interruption or a slowing of the segregation process, as found in some experiments. Finally, at very low frequencies, the morphology of domains is characterized by lamellar order everywhere in the system resembling what happens in the case with steady shear.Comment: 1 table and 12 figures in .gif forma

0.7-anomaly and magnetotransport of disordered quantum wires

The unexpected "0.7" plateau of conductance quantisation is usually observed for ballistic one-dimensional devices. In this work we study a quasi-ballistic quantum wire, for which the disorder induced backscattering reduces the conductance quantisation steps. We find that the transmission probability resonances coexist with the anomalous plateau. The studies of these resonances as a function of the in-plane magnetic field and electron density point to the presence of spin polarisation at low carrier concentrations and constitute a method for the determination of the effective g-factor suitable for disordered quantum wires.Comment: 4 pages, 6 figure