Affleck-Dine Baryogenesis and heavy elements production from Inhomogeneous Big Bang Nucleosynthesis

We study the impact of possible high density baryonic bubbles on the early formed QSO, IGM, and metal poor stars. Such bubbles could be created, under certain conditions, in Affleck-Dine model of baryogenesis and may occupy a relatively small fraction of space, while the dominant part of the cosmological volume has the normal observed baryon-to-photon ratio $\eta = 6\cdot 10^{-10}$. The value of $\eta$ in the bubbles, could be much larger than the usually accepted one (it might be even close to unity) without contradicting the existing data on light element abundances and the observed angular spectrum of CMBR. We find upper bounds on $\eta$ by comparing heavy elements' abundances produced in BBN and those of metal poor stars. We conclude that $\eta$ should be smaller than $10^{-5}$ in some metal poor star regions.Comment: 11 pages, 4 figures, PTPTeX ; added references, changed introduction, acknowledgments and figure

Reply to 'Comment on 'Heavy element production in inhomogeneous big bang nucleosynthesis''

This is a reply report to astro-ph/0604264. We studied heavy element production in high baryon density region in early universe astro-ph/0507439. However it is claimed in astro-ph/0604264 that small scale but high baryon density region contradicts observations for the light element abundance or in order not to contradict to observations high density region must be so small that it cannot affect the present heavy element abundance. In this paper we study big bang nucleosynthesis in high baryon density region and show that in certain parameter spaces it is possible to produce enough amount of heavy element without contradiction to CMB and light element observations.Comment: 7 pages, 4 figures, References added, one more reference adde

Heavy Element Production in Inhomogeneous Big Bang Nucleosynthesis

We present a new astrophysical site of the big bang nucleosynthesis (BBN) that are very peculiar compared with the standard BBN. Some models of the baryogenesis suggest that very high baryon density regions were formed in the early universe. On the other hand, recent observations suggest that heavy elements already exist in high red-shifts and the origin of these elements become a big puzzle. Motivated by these, we investigate BBN in very high baryon density regions. BBN proceeds in proton-rich environment, which is known to be like the p-process. However, by taking very heavy nuclei into account, we find that BBN proceeds through both the p-process and the r-process simultaneously. P-nuclei such as 92Mo, 94Mo, 96Ru, 98Ru whose origin is not well known are also synthesized.Comment: 6 pages, 7 figure

Functional shoulder radiography with use of a dynamic flat panel detector

Our purpose in this study was to develop a functional form of radiography and to perform a quantitative analysis for the shoulder joint using a dynamic flat panel detector (FPD) system. We obtained dynamic images at a rate of 3.75 frames per second (fps) using an FPD system. Three patients and 5 healthy controls were studied with a clinically established frontal projection, with abduction of the arms. The arm angle, glenohumeral angle (G-angle), and scapulothoracic angle (S-angle) were measured on dynamic images. The ratio of the G-angle to the S-angle (GSR) was also evaluated quantitatively. In normal subjects, the G-angle and S-angle changed gradually along with the arm angle. The G-angle was approximately twice as large as the S-angle, resulting in a GSR of 2 throughout the abduction of the shoulder. Changes in G-angle and S-angle tended to be irregular in patients with shoulder disorders. The GSR of the thoracic outlet syndrome, recurrent dislocation of the shoulder joint, and anterior serratus muscle paralysis were 3-7.5, 4-9.5, and 3.5-7.5, respectively. The GSR of the anterior serratus muscle paralysis improved to approximately 2 after orthopedic treatment. Our preliminary results indicated that functional radiography by FPD and computer-aided quantitative analysis is useful for diagnosis of some shoulder disorders, such as the thoracic outlet syndrome, recurrent dislocation of the shoulder joint, and anterior serratus muscle paralysis. The technique and procedures described comprise a simple, functional shoulder radiographic method for evaluation of the therapeutic effects of surgery and/or rehabilitation. © 2014 The Author(s)

A Feasibility Study of Postoperative Adjuvant Therapy of Carboplatin and Weekly Paclitaxel for Completely Resected Non-small Cell Lung Cancer

IntroductionRecent clinical trials have shown significant survival benefits from postoperative adjuvant therapy for respectable nonsmall cell lung cancer (NSCLC). However, evaluation of adjuvant chemotherapy with carboplatin combination is still uncertain. The purpose of the study was to test the feasibility of adjuvant chemotherapy with carboplatin and separate weekly paclitaxel after complete resection of pStage IB, II, IIIA NSCLC in a multicenter study.MethodsThe study was conducted from 2001 to 2006 in the outpatient setting. A total of 61 patients were enrolled. Patients received adjuvant chemotherapy with 4 cycles of carboplatin (AUC 5) on day 1 and paclitaxel (70 mg/m2) on day 1, 8, and 15 every 4 weeks. Primary endpoints were toxicity and chemotherapy compliance. Secondary endpoints were disease-free survival and overall survival.ResultsMore than 65% of eligible patients had pStage IIIA. The median number of chemotherapy cycles was 4 (range 1–4). Grade 3 or 4 toxicities of neutropenia were 34% (grade 4: 2%). Other hematologic adverse effects were extremely less frequent. Regarding the nonhematologic adverse effect, hair loss was frequent; however, peripheral neuralgia was less frequent. Treatment-related death was not registered. During median follow-up of 21 months, 24 patients developed recurrent disease. Estimated disease-free survival and overall survival at 2 years was 51.2% and 84.6%, respectively.ConclusionsPostoperative carboplatin and weekly paclitaxel showed favorable feasibility and acceptable toxicity in comparison with the cisplatin-containing regimen. Consequently, it is desirable that this regimen would be validated in a phase III clinical trial for NSCLC after curative resection

Gastric variceal bleeding caused by an intrahepatic arterioportal fistula that formed after liver biopsy: a case report and review of the literature

An intrahepatic arterioportal fistula is a rare cause of portal hypertension and variceal bleeding. We report on a patient with an intrahepatic arterioportal fistula following liver biopsy who was successfully treated by hepatectomy after unsuccessful arterial embolization. We also review the literature on symptomatic intrahepatic arterioportal fistulas after liver biopsy. A 48-year-old male with bleeding gastric varices and hepatitis B virus-associated liver cirrhosis was transferred to our hospital; this patient previously underwent percutaneous liver biopsies 3 and 6 years ago. Abdominal examination revealed a bruit over the liver, tenderness in the right upper quadrant, and splenomegaly. Ultrasonographic examination, computed tomography, and angiography confirmed an arterioportal fistula between the right hepatic artery and the right portal vein with portal hypertension. After admission, the patient suffered a large hematemesis and developed shock. He was treated with emergency transarterial embolization using microcoils. Since some collateral vessels bypassed the obstructive coils and still fed the fistulous area, embolization was performed again. Despite the second embolization, the collateral vessels could not be completely controlled. Radical treatment involving resection of his right hepatic lobe was performed. For nearly 6 years postoperatively, this patient has had no further episodes of variceal bleeding