1,818 research outputs found

    A prospective study to evaluate functional results of PHILOS locking plate system in management of proximal humerus fractures in adults

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    Background: Various management options are available for management of proximal humerus fractures where PHILOS plating is one of them. But data available in literature on its use and efficacy in management of all types of proximal humerus fractures is still dicey. So, we through our study attempted to grow our knowledge regarding its functional results, complication rates, etc. for use in coming future.Methods: 30 patients with proximal humerus fractures classified on the basis of Neer’s classification were included in study who were operated from 2018 to 2020 at our institute. These patients were operated by PHILOS locking plate system with either delto-pectoral or trans-deltoid approach and they are followed up at regular intervals to assess them clinicoradiologicallly and functionally by Neer’s criteria.Results: In our study we found maximum incidence of these fracture between age group of 40-80 years (66.66%) with male to female ratio of 2:1 with 19 patients having left sided and 11 patients having right sided proximal humerus fracture. Complications were found in 11 patients (36.67%). Functional evaluation was carried out using Neer’s criteria at final follow up which came to excellent results in 3, satisfactory in 18, unsatisfactory in 7 and failure in 2 patients. Average time of fracture union was 12.62 weeks.Conclusions: PHILOS locking plate system serves good purpose in management of fractures of proximal humerus but requires trained faculty to do this operation who has detailed knowledge about shoulder anatomy and mechanism of injury to reduce complications associated with this type of modality

    A Pulsed-air Model of Blue Whale B Call Vocalizations

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    Blue whale sound production has been thought to occur by Helmholtz resonance via air flowing from the lungs into the upper respiratory spaces. This implies that the frequency of blue whale vocalizations might be directly proportional to the size of their sound-producing organs. Here we present a sound production mechanism where the fundamental and overtone frequencies of blue whale B calls can be well modeled using a series of short-duration (\u3c1 \u3es) wavelets. We propose that the likely source of these wavelets are pneumatic pulses caused by opening and closing of respiratory valves during air recirculation between the lungs and laryngeal sac. This vocal production model is similar to those proposed for humpback whales, where valve open/closure and vocal fold oscillation is passively driven by airflow between the lungs and upper respiratory spaces, and implies call frequencies could be actively changed by the animal to center fundamental tones at different frequency bands during the call series

    Striking the right balance in right whale conservation

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    Author Posting. © The Authors, 2009. This article is posted here by permission of NRC Research Press for personal use, not for redistribution. The definitive version was published in Canadian Journal of Fisheries and Aquatic Sciences 66 (2009): 1399-1403, doi:10.1139/F09-115.Despite many years of study and protection, the North Atlantic right whale (Eubalaena glacialis) remains on the brink of extinction. There is a crucial gap in our understanding of their habitat use in the migratory corridor along the eastern seaboard of the United States. Here, we characterize habitat suitability in migrating right whales in relation to depth, distance to shore, and the recently enacted ship speed regulations near major ports. We find that the range of suitable habitat exceeds previous estimates and that, as compared with the enacted 20 nautical mile buffer, the originally proposed 30 nautical mile buffer would protect more habitat for this critically endangered species.This work was supported in part by SERDP/DoD grant W912HQ-04-C-0011 to A.J. Read and P.N. Halpin as well as a James B. Duke Fellowship and a Harvey L. Smith Dissertation Year Fellowship to R.S. Schick

    BioNoMo. The biodiversity network of Mozambique

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    Mozambique biodiversity richness plays a pivotal role to achieve the sustainable development of the country. However, Mozambique's flora and fauna diversity still remains broadly unknown and poorly documented. To properly address this issue, one of the strategic needs expressed by the Mozambican institutions was the development of a national biodiversity data repository to aggregate, manage and make data available online. Thus, a sustainable infrastructure for the standardisation, aggregation, organisation and sharing of primary biodiversity data was developed. Named the "Biodiversity Network of Mozambique" (BioNoMo), such a tool serves as a national repository of biodiversity data and aggregates occurrence records of plants and animals in the country obtained from floristic and faunistic observations and from specimens of biological collections. In this paper, the authors present the structure and data of BioNoMO, including software details, the process of data gathering and aggregation, the taxonomic coverage and the WebGIS development. Currently, aggregating a total of 273,172 records, including 85,092 occurrence records of plants and 188,080 occurrence records of animals (41.2% terrestrial, 58,8% aquatic), BioNoMo represents the largest aggregator of primary biodiversity data in Mozambique and it is planned to grow further by aggregating new datasets

    Superdeformed rotational bands in Pu-240

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    The intermediate structure of the fission resonances has been observed in Pu-240. A resonance structure found around the excitation energy of 4.5 MeV was interpreted as a group of K-pi = 0(+) superdeformed rotational bands. The moments of inertia and level density distributions were also deduced for the individually observed band-heads

    Universal Vectorial and Ultrasensitive Nanomechanical Force Field Sensor

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    Miniaturization of force probes into nanomechanical oscillators enables ultrasensitive investigations of forces on dimensions smaller than their characteristic length scale. Meanwhile it also unravels the force field vectorial character and how its topology impacts the measurement. Here we expose an ultrasensitive method to image 2D vectorial force fields by optomechanically following the bidimensional Brownian motion of a singly clamped nanowire. This novel approach relies on angular and spectral tomography of its quasi frequency-degenerated transverse mechanical polarizations: immersing the nanoresonator in a vectorial force field does not only shift its eigenfrequencies but also rotate eigenmodes orientation as a nano-compass. This universal method is employed to map a tunable electrostatic force field whose spatial gradients can even take precedence over the intrinsic nanowire properties. Enabling vectorial force fields imaging with demonstrated sensitivities of attonewton variations over the nanoprobe Brownian trajectory will have strong impact on scientific exploration at the nanoscale

    The Static and Dynamic Lattice Changes Induced by Hydrogen Adsorption on NiAl(110)

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    Static and dynamic changes induced by adsorption of atomic hydrogen on the NiAl(110) lattice at 130 K have been examined as a function of adsorbate coverage. Adsorbed hydrogen exists in three distinct phases. At low coverages the hydrogen is itinerant because of quantum tunneling between sites and exhibits no observable vibrational modes. Between 0.4 ML and 0.6 ML, substrate mediated interactions produce an ordered superstructure with c(2x2) symmetry, and at higher coverages, hydrogen exists as a disordered lattice gas. This picture of how hydrogen interacts with NiAl(110) is developed from our data and compared to current theoretical predictions.Comment: 36 pages, including 12 figures, 2 tables and 58 reference

    Neuroinflammation, Mast Cells, and Glia: Dangerous Liaisons

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    The perspective of neuroinflammation as an epiphenomenon following neuron damage is being replaced by the awareness of glia and their importance in neural functions and disorders. Systemic inflammation generates signals that communicate with the brain and leads to changes in metabolism and behavior, with microglia assuming a pro-inflammatory phenotype. Identification of potential peripheral-to-central cellular links is thus a critical step in designing effective therapeutics. Mast cells may fulfill such a role. These resident immune cells are found close to and within peripheral nerves and in brain parenchyma/meninges, where they exercise a key role in orchestrating the inflammatory process from initiation through chronic activation. Mast cells and glia engage in crosstalk that contributes to accelerate disease progression; such interactions become exaggerated with aging and increased cell sensitivity to stress. Emerging evidence for oligodendrocytes, independent of myelin and support of axonal integrity, points to their having strong immune functions, innate immune receptor expression, and production/response to chemokines and cytokines that modulate immune responses in the central nervous system while engaging in crosstalk with microglia and astrocytes. In this review, we summarize the findings related to our understanding of the biology and cellular signaling mechanisms of neuroinflammation, with emphasis on mast cell-glia interactions
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