Polarographic Studies on Complexes of Pd(II) & Co(II) with Triethanolamine

721-72

SOLVENT EFFECTS ON THE ELECTRONIC ABSORPTION SPECTRA OF SOME ANALYTICAL INDICATORS

Electronic absorption spectra of selected ligands (Alloxan, Carmine, Naphthol Yellow S, Hematoxylin and Cyanine) were recorded in presence of different solvents (H2O, Ethyl acetate, Ethanol, DMF, Isopropyl alcohol, Amyl alcohol and Butanol) of variable physical properties. The electronic transitions were assigned. The data are analyzed based on the multiple linear regression technique explained from the views of different solvent parameters. Statistical analyses of the effect of solvents on the electronic spectra of the present ligands have been investigated

Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic

Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality. Methods Prospective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months. Results All-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3-11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality. Conclusions Children with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer

Equilibria for Interaction between Hematoxylin & Iron(III), Cobalt(II), Nickel(II) & Copper(II)

323-32

Acid Dissociation Constants of Some Schiff Bases

149-15

Spectrophotometric & Potentiometric Studies of Some Multidentate Schiff Bases & Their Complexes

855-85

Studies on Some Monomeric & Polymeric Schiff Bases Derived from 5-Vinylsalicylaldehyde Derivatives & Their Metal Complexes

918-92

Extraction of Iron(III) Azido Complexes with Monooctyl-ɑ-anilinobenzylphosphonate

101-10

Solvent, substituents and pH effects towards the spectral shifts of some highly colored indicators

The solvatochromic responses of six indicators namely Sudan orange, Alizarin yellow R, Aurin tricarboxylic acid, Alizarin yellow GG, Titan yellow and Eriochrome black-T, dissolved in seven solvents of different polarities, have been measured at room temperature. The UV/Vis absorption spectral shifts were analyzed by the multiple linear regression analysis and Kamlet–Taft equation. The observed solvatochromism was found to depend on the presence of the donor and acceptor substituents in the conjugated systems of the indicator and the physical properties of the solvent molecules. The pH effects on the wavenumbers of the absorption band maxima of some indicators with different constituents at room temperature were discussed and the mechanism of ionization was explained. The dissociation constants (pKa) of the investigated compounds were precisely assessed and the existence of the individual predominant ionic species was assigned by constructing distribution diagrams at different pH ranges