Investigation on the infection of Capoeta capoeta with Clinonstomum and its life cycle in the Shirrod River

This is the first report on the C. capoeta infestation with C. complanatum. 112 fish sampled and surveyed for the likely infection with C. complanatum. Using the length group, extent of contamination, sex, infected organs and number of parasites in each organ, various graphs prepared. It was concluded that female fish were the most infected with decreasing percent of infestation as the body length increased. Gill cavity and pharynx were demonstrated to be the main contaminated areas and ten parasite per fish was the greatest number recorded. Contaminated organs were subject to pathological studies. Since birds are the end host separated metacercariae were fed to 15 chicks and their maturity stages was investigated at different time intervals in contaminated organs. The parasites were mature after three days

In vitro Susceptibility of Helicobacter pylori to Licorice Extract

Abstract Helicobacter pylori is the causative agent of gastritis and peptic ulcer disease. Eradication of H. pylori is hard to achieve and often require multiple antibiotics regimens. These regimens are quite expensive and have substantial side effects. Licorice is a traditional drug which is frequently used for gastric discomforts in Iran. The susceptibility of H. pylori to the extract of licorice has been investigated in the present study. One hundred and eighty clinical H. pylori strains were isolated in this study. For comparison and control, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were also included in this study. Agar dilution assay was used to test the susceptibility of the clinical isolates of H. pylori to the Glycyrrhiza extract at different concentration. The assay plates had 25, 50, 100, 150, 200, 300 and 400 mg/ml of licorice extract. Licorice extract inhibited the H. pylori strains with a MIC range of 50-400 mg/ml. The present results show that therapeutically administered concentrations of licorice extract could have growth-inhibiting effect on H. pylori in vitro. The above preliminary experiments indicated strongly that licorice extract has some anti-H. pylori property and H. pylori shows susceptibility to licorice extract in concentration ranges that are achievable in the stomach. The resistance of other bacterial species indicates the possibility of selective therapy without adverse effects on the normal bacterial flora

Association between splenectomy and pulmonary hypertension in patients with major beta- thalassemia

Background and purpose: Increased pressure in the pulmonary circulation is of the major factors causing cardiac disorders in patients with thalassemia. The aim of this study was to investigate the relationship between splenectomy and pulmonary arterial pressure in individuals with beta- thalassemia major. Materials and methods: A cross-sectional study was carried out in patients with beta-thalassemia attending Hajar Hospital Shahrekord, Iran, 2015. All patients underwent echocardiography and the hemoglobin levels, platelet count, ferritin, pressure, pulmonary arterial pressure, etc. were measured. Data analysis was done in Stata 13. Results: Among the variables measured, the average age, hemoglobin level, platelet count, nucleated RBC, lactate dehydrogenase, tricuspid regurgitation flow, pulmonary arterial pressure, right diameter, main pulmonary diameter, left ventricular end diastolic diameter, left ventricular end systolic diameter were found to be higher in patients with splenectomy, compared to those of the patients without splenectomy (P> 0.05). Significant correlation was observed between platelets, NRBC and the time of splenectomy with pulmonary artery pressure (P 0.05). Conclusion: The results showed that splenectomy could increase the susceptibility to pulmonary artery pressure in patients with beta thalassemia major or lead to the progression of pulmonary hypertension in this disease

Association between Splenectomy and Pulmonary Hypertension in Patients with Major Beta- Thalassemia

Background and purpose: Increased pressure in the pulmonary circulation is of the major factors causing cardiac disorders in patients with thalassemia. The aim of this study was to investigate the relationship between splenectomy and pulmonary arterial pressure in individuals with beta- thalassemia major. Materials and methods: A cross-sectional study was carried out in patients with beta- thalassemia attending Hajar Hospital Shahrekord, Iran, 2015. All patients underwent echocardiography and the hemoglobin levels, platelet count, ferritin, pressure, pulmonary arterial pressure, etc. were measured. Data analysis was done in Stata 13. Results: Among the variables measured, the average age, hemoglobin level, platelet count, nucleated RBC, lactate dehydrogenase, tricuspid regurgitation flow, pulmonary arterial pressure, right diameter, main pulmonary diameter, left ventricular end diastolic diameter, left ventricular end systolic diameter were found to be higher in patients with splenectomy, compared to those of the patients without splenectomy (P> 0.05). Significant correlation was observed between platelets, NRBC and the time of splenectomy with pulmonary artery pressure (P 0.05). Conclusion: The results showed that splenectomy could increase the susceptibility to pulmonary artery pressure in patients with beta thalassemia major or lead to the progression of pulmonary hypertension in this disease