Improved Quantum Cost for n-bit Toffoli Gates

We present an n-bit Toffoli gate quantum circuit based on the realization proposed by Barenco, where some of the Toffoli gates in their construction are replaced with Peres gates. This results in a significant cost reduction. Our main contribution is a quantum circuit which simulates the (m+1)-bit Toffoli gate with 32m-96 elementary quantum gates and one garbage bit which is passed unchanged. This paper is a corrected and expanded version of our recent journal publication

Propagation of fluctuations in interaction networks governed by the law of mass action

Using an example of physical interactions between proteins, we study how perturbations propagate in interconnected networks whose equilibrium state is governed by the law of mass action. We introduce a comprehensive matrix formalism which predicts the response of this equilibrium to small changes in total concentrations of individual molecules, and explain it using a heuristic analogy to a current flow in a network of resistors. Our main conclusion is that on average changes in free concentrations exponentially decay with the distance from the source of perturbation. We then study how this decay is influenced by such factors as the topology of a network, binding strength, and correlations between concentrations of neighboring nodes. An exact analytic expression for the decay constant is obtained for the case of uniform interactions on the Bethe lattice. Our general findings are illustrated using a real biological network of protein-protein interactions in baker's yeast with experimentally determined protein concentrations.Comment: 4 pages; 2 figure