25 research outputs found
<Abstract of Published Report>Formulation of Gel-Formation Ointments with Hydrophilic Polymers for Treatment of Recovery Stage of Bedsore.
<Abstract of Published Report>Modification of the Physicochemical Properties of Minocycline Hydrochloride Ointment with Cyclodextrines for Optimum Treatment of Bedsore.
<Abstract of Published Report>Formulation Design of Ointment Base Suitable for Healing of Lesions in Treatment of Bedsores.
<Abstract of Published Report>Mixed Base of Hydrophilic Ointment and Purified Lanolin to Improve the Drug Release Rate and Absorption of Water of Minocycline Hydrochloride Ointment for Treatment of Bedsores.
<Abstract of Published Report>Preparation of a Gel-Forming Ointment Base Applicable to the Recovery Stage of Bedsore and Clinical Evaluation of a Treatment Method with Different Ointment Bases Suitable to each Stage of Bedsore.
Ablation of TSC2 Enhances Insulin Secretion by Increasing the Number of Mitochondria through Activation of mTORC1
) mice. The present study examines the effects of TSC2 ablation on insulin secretion from pancreatic beta cells. mice and TSC2 knockdown insulin 1 (INS-1) insulinoma cells treated with small interfering ribonucleic acid were used to investigate insulin secretion, ATP content and the expression of mitochondrial genes. mice exhibit hyperinsulinemia due to an increase in the number of mitochondria as well as enlargement of individual beta cells via activation of mTORC1.Activation of mTORC1 by TSC2 ablation increases mitochondrial biogenesis and enhances insulin secretion from pancreatic beta cells