The diversity of mouse osteoblasts at the single cell level, using machine learning

内容の要約広島大学(Hiroshima University)博士(歯学)Doctor of Philosophy in Dental Sciencedoctora

Vanishing Love of Black Holes in General Relativity: From Spacetime Conformal Symmetry of a Two-dimensional Reduced Geometry

We study the underlying structure of the vanishing of the Love numbers of both Schwarzschild and Kerr black holes in terms of spacetime conformal symmetry in a unified manner for the static spin-$s$ fields. The perturbations can be reduced with the harmonic decomposition to a set of infinite static scalar fields in a two-dimensional anti-de Sitter spacetime~$({\rm AdS}_2)$. In the reduced system, each scalar field is paired with another, implying that all multipole modes of the perturbation can be regarded as symmetric partners, which can be understood from the property of the supersymmetry algebra. The generator of the supersymmetric structure is constructed from a closed conformal Killing vector field of ${\rm AdS}_2$. The associated conserved quantity allows one to show no static response, i.e., vanishing of the Love and dissipation numbers. We also discuss the vanishing Love numbers of the Kerr black hole with the nonzero dissipation numbers for the non-axisymmetric perturbations in terms of a radial constant found in a parallel manner as the axisymmetric field case even though the interpretation for the structure is controversial. The symmetric structure corresponds to the ``ladder'' symmetry in Hui et al. [JCAP 01, no.01, 032 (2022)] although the geometrical origin is different. Our ladder operator includes the generators of hidden symmetries in previous works.Comment: 41 pages, v2: added discussion on the result of the Kerr black hole in terms of the Teukolsky equation, v3: minor corrections, accepted for publication in PR

Room Temperature Ferromagnetic Semiconductor Rutile Ti1-xCoxO2-\delta Epitaxial Thin Films Grown by Sputtering Method

Room temperature ferromagnetic semiconductor rutile Ti1-xCoxO2-\delta (101) epitaxial thin films were grown on r-sapphire substrates by a dc sputtering method. Ferromagnetic magnetization, magnetic circular dichroism, and anomalous Hall effect were clearly observed at room temperature in sputter-grown films for the first time. The magnetization value is nearly as large as 3\mu B/Co that is consistent with the high spin state Co2+ in this compound recently established by spectroscopic methods. Consequently, its originally large magneto-optical response is further enhanced.Comment: 15 pages, 4 figure

Hepatitis B virus genotype assignment using restriction fragment length polymorphism patterns

AbstractHepatitis B virus (HBV) is classified into genotypes A–F, which is important for clinical and etiological investigations. To establish a simple genotyping method, 68 full-genomic sequences and 106 S gene sequences were analyzed by the molecular evolutionary method. HBV genotyping with the S gene sequence is consistent with genetic analysis using the full-genomic sequence. After alignment of the S sequences, genotype specific regions are identified and digested by the restriction enzymes, HphI, NciI, AlwI, EarI, and NlaIV. This HBV genotyping system using restriction fragment length polymorphism (RFLP) was confirmed to be correct when the PCR products of the S gene in 23 isolates collected from various countries were digested with this method. A restriction site for EarI in genotype B was absent in spite of its presence in all the other genotypes and genotype C has no restriction site for AlwI. Only genotype E is digested with NciI, while only genotype F has a restriction site for HphI. Genotype A can be distinguished by a single restriction enzyme site for NlaIV, while genotype D digestion with this enzyme results in two products that migrates at 265 and 186 bp. This simple and accurate HBV genotyping system using RFLP is considered to be useful for research on HBV