1,613 research outputs found
Geometric Quantization on a Coset Space G/H
Geometric quantization on a coset space is considered, intending to
recover Mackey's inequivalent quantizations. It is found that the inequivalent
quantizations can be obtained by adopting the symplectic 2-form which leads to
Wong's equation. The irreducible representations of which label the
inequivalent quantizations arise from Weil's theorem, which ensures a Hermitian
bundle over to exist.Comment: 12 pages, LateX2
Constraint on the ejecta mass for a black hole-neutron star merger event candidate S190814bv
We derive the upper limit to the ejecta mass of S190814bv, a black
hole-neutron star merger candidate, through the radiative transfer simulations
for kilonovae with the realistic ejecta density profile as well as the detailed
opacity and heating rate models. The limits to the ejecta mass strongly depend
on the viewing angle. For the face-on observations (), the total
ejecta mass should be smaller than for the average distance of
S190814bv ( Mpc), while larger mass is allowed for the edge-on
observations. We also derive the conservative upper limits of the dynamical
ejecta mass to be , , and for the
viewing angle , , and for ,
respectively. We show that the {\it iz}-band observation deeper than mag
within 2 d after the GW trigger is crucial to detect the kilonova with the
total ejecta mass of at the distance of Mpc. We also
show that a strong constraint on the NS mass-radius relation can be obtained if
the future observations put the upper limit of to the dynamical
ejecta mass for a BH-NS event with the chirp mass smaller than and effective spin larger than .Comment: 16 pages, 15 figure
Complement regulatory proteins in glomerular diseases
Complement regulatory proteins in glomerular diseases. Complement activation plays a critical role in the pathogenesis of many forms of glomerulonephritis. Complement activation leads to tissue injury through various mechanisms including the generation of chemotactic factors and activation of the resident glomerular cells following C5b-9 insertion. Recent advances have disclosed the mechanisms of regulation of complement activation by discovery of a number of complement regulatory proteins. Decay accelerating factor (DAF), membrane cofactor protein (MCP), and complement receptor type 1 (CR1) act by inactivating C3/C5 convertase. They belong to the gene superfamily known as the regulators of complement activation (RCA), and share a common structural motif called a short consensus repeat (SCR). In contrast, CD59 works by inhibiting formation of C5b-9. The glomerulus is particularly well endowed with these membrane-bound complement regulatory proteins. DAF, MCP, and CD59 are ubiquitously expressed by all three resident glomerular cells, while CR1 is localized exclusively in podocytes. Expression of complement regulatory proteins can be changed by many factors including complement attack itself, and their expression levels are affected in various glomerular disorders. Studies utilizing cultured glomerular cells and animal models of glomerular diseases suggest important protective roles of complement regulatory proteins against immune-mediated renal injury. Recent progress in molecular biological techniques has made new therapeutic strategy feasible. Systemic administration of soluble recombinant complement regulatory proteins and local overexpression of complement regulatory proteins are promising therapeutic approaches
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