String tension and string susceptibility in two-dimensional generalized Weingarten model

We study the two-dimensional generalized Weingarten model reduced to a point, which interpolates reduced Weingarten model and the large-N gauge theory. We calculate the expectation value of the Wilson loop using Monte-Carlo method and determine the string tension and string susceptibility. The numerical result suggests that the string susceptibility approaches to -2 in a certain parametric region, which implies that the branched-polymer configurations are suppressed.Comment: 13 pages; typos correcte

Unrenormalizable Theories Can Be Predictive

Unrenormalizable theories contain infinitely many free parameters. Considering these theories in terms of the Wilsonian renormalization group (RG), we suggest a method for removing this large ambiguity. Our basic assumption is the existence of the maximal ultraviolet cutoff in a cutoff theory, and we require that the theory be so fine-tuned as to reach the maximal cutoff. The theory so obtained behaves as a local continuum theory to the shortest distance. In concrete examples of the scalar theory we find that at least in a certain approximation to the Wilsonian RG, this requirement enable us to make unique predictions in the infrared regime in terms of a finite number of independent parameters. Therefore, the method might provide a way for calculating quantum corrections in a low-energy effective theory of quantum gravity.Comment: 33 pages, TeX, 14 figure

Extra dimensions prefer large tan⁡β\tan\beta

Assuming that the recent result obtained from the Monte Carlo simulations on the nonperturbative existence of the pure SU(2) Yang-Mills theory in five dimensions can be applied to a more general class of higher-dimensional gauge theories, we derive the conditions imposed by the nontriviality requirement on the theories. We find that the supersymmetric grand unified theories with extra dimensions prefer a large value (\gsim 2) of $\tan\beta$ of the minimal supersymmetric standard model, in accord with today's possible observation of the Higgs particle at LEP2.Comment: 26 pages, TeX, 7 figure

Phase structure of the large-N reduced gauge theory and generalized Weingarten model

We study a generalization of Weingarten model reduced to a point, which becomes the large-N reduced U(N) gauge theory in a special limit. We find that the U(1)^d symmetry is broken one by one, and restored simultaneously as U(1)^d -> U(1)^{d-1} -> ... -> U(1) -> 1 -> U(1)^d as we change the coupling constants. In this model we can develop an efficient algorithm and we can see the phase structure of large-N reduced model clearly, and therefore this model would be useful for the study of the unitary model.Comment: LaTeX-2e, 11 pages with 11 figures; typos correcte

Phase II Trial of Biweekly Paclitaxel and Gemcitabine as Second-Line Chemotherapy for Non-Small Cell Lung Cancer Previously Treated with Platinum-Based Chemotherapy

A phase II study was conducted to evaluate the feasibility and efficacy of biweekly administration of paclitaxel and gemcitabine in patients with non-small cell lung cancer (NSCLC) who had been treated previously with platinum-based chemotherapy. Paclitaxel (150 mg/m2) and gemcitabine (1,000 mg/m2) were administered biweekly for at least 4 cycles. Thirty-one patients with a median age of 64 years (39-75 years) were enrolled in this study(stage IIIB/IV :11/20,PS 0/1/2:13/16/2).Partial response was observed in 7 cases (23%), and stable disease was seen in 18 cases (58%).Median survival time was 8.8 months with a one-year survival rate of 41.9 %.Hematological toxicities were mild and neutropenia of grade 3 or above was observed in one patient (3%). Non-hematological toxicities were also mild, including neurotoxicity (3%). Biweekly paclitaxel and gemcitabine combination chemotherapy was effective and tolerated well as second-line therapy against NSCLC.Article信州医学雑誌 59(6): 411-418(2011)departmental bulletin pape

Diffuse Endobronchial Wall Spread of Metastatic Breast Cancer

We present here a case of diffuse tracheobronchial wall spread of metastatic breast cancer who was successfully treated with trastuzumab plus vinorelbine chemotherapy. The patient had a left radical mastectomy for breast cancer in March 2000 and developed persistent cough and dyspnea in November 2006. Pulmonary function test demonstrated an obstructive pattern. Chest computed tomography showed a wall thickening of trachea and right side bronchus, but radiographic findings including 18F-fluorodeoxyglucose positron emission tomography failed to detect the locations of disease in the lung. The findings on bronchofiberscopy showed edematous tracheobronchial mucosa, but also failed to visually detect direct masses. Transbronchial biopsy specimens revealed involvement of metastatic breast cancer. The patient was treated with trastuzumab plus vinorelbine chemotherapy and the wall thickening of bronchial tree and clinical symptoms were improved. Although endobronchial metastasis in metastatic breast cancer is not uncommon, diffuse spread without forming intraluminal mass is extremely rare. The pattern of endobronchial metastasis should be considered in patients with malignancies even when radiographic abnormalities are undetectable

Comparison of Distance of 6-min Walk Test and the Incremental Shuttle Walk Test with Lung Function or Quality of Life in Patients with Chronic Obstructive Pulmonary Disease

Article信州医学雑誌 61(2):57-64(2013)journal articl

Slope efficiency characteristics of mode-hop driven tunable single-mode cholesteric liquid crystal laser

SPIE Photonic Devices + Applications, 2011, San Diego, California, United StatesYo Inoue, Hiroyuki Yoshida, Kenta Inoue, Yusuke Shiozaki, Hitoshi Kubo, Akihiko Fujii, and Masanori Ozaki "Slope efficiency characteristics of mode-hop driven tunable single-mode cholesteric liquid crystal laser", Proc. SPIE 8114, Liquid Crystals XV, 811415 (7 September 2011). DOI: https://doi.org/10.1117/12.89320

Analyses of the characteristics of potential and cross-talk at each electrode in electro-oculogram

We placed negative electrodes on the body and positive electrodes at the medial and lateral canthi, measured their potentials separately, evaluated their characteristics, and analyzed cross-talk. We recorded EOG in 6 normal subjects and found the following. The potential at the medial was lower than that at the lateral canthus in the bilateral eyes. The polarity of waves at the lateral was reverse to that at the medial canthus in the bilateral eyes. We recorded EOG in 6 patients with unilateral anophthalmia and found the following. On the anophthalmia side, the potential at the lateral was considerably lower than that at the medial canthus. The polarity of the potential was the same between the medial and lateral canthi. The mean cross-talk to the medial canthus on the anophthalmia side was 8.7%- 54.0% of the potential at the medial canthus on the normal side. The mean cross-talk to the lateral canthus on the anophthalmia side was 4.4%-16.9%. The influence of cross-talk of the other eye was marked at the medial but slight at the lateral canthus. In EOG recording, results with minimum errors due to cross-talk can be obtained by paying attention to the potential at the lateral canthus

日本人の免疫性血栓性血小板減少性紫斑病患者における不十分な血漿交換は致死的な転帰と強く相関する

Plasma exchange (PEX) using fresh frozen plasma has considerably reduced the mortality rate in patients with immune-mediated thrombotic thrombocytopenic purpura (iTTP). However, some patients still do not survive even with treatment, but little information is available regarding which treatment these patients received. This study was conducted to obtain this information in 240 patients who met the current iTTP diagnostic criteria and completed at least 30 days of follow-up except for deceased cases. These patients were divided into three groups: survivors (n = 195), TTP-related deaths (n = 32), and other cause of death (n = 13). In the TTP-related death group, 26 of 32 patients experienced sudden death, mostly following radical hypotension and bradycardia. The median follow-up time after admission was 5.0 days, and the median number of PEX sessions was 2.5. Nine patients underwent autopsy and had cardiac microvascular thrombi in arterioles. Levels of lactate dehydrogenase, total bilirubin, serum creatinine, and D-dimer were significantly higher in the TTP-related death group than in the survivors group. Frequent PEX (> 20 sessions) was not associated with TTP-related death. In the acute phase of iTTP, patients with substantial organ damage caused by microthrombi have a greater mortality risk, even after just a few PEX sessions.博士（医学）・乙第1518号・令和3年12月21日© Japanese Society of Hematology 2021.The version of record of this article, first published in International journal of hematology, is available online at Publisher’s website: http://dx.doi.org/10.1007/s12185-021-03197-5.発行元が定める登録猶予期間終了の後、本文を登録予定（2022.10