Small Cell Carcinoma of the Ureter with Malignant Lymphoma: Case Report and Literature Review

A 78-year-old man was referred to our hospital for gross hematuria. Ultrasonography and magnetic resonance urography revealed tumor in the right lower ureter. Computed tomography revealed right cervical lymph node swelling and pathological diagnosis was diffuse large B-cell lymphoma. Right nephroureterectomy was performed and pathologic examination revealed small cell carcinoma of the ureter with a small urothelial cell carcinoma component. As the patient had concomitant other malignancies, additional systemic chemotherapy was not performed. As of 3 months after operation, postoperative course has been uneventful. Only 11 cases of primary small cell carcinoma of the ureter have been described

Primary Omental Myxoid Leiomyosarcoma: Report of a Case and a Review of the Literature

A 41-year-old Japanese woman who presented with right lower abdominal pain underwent partial omental resection with tumor excision, leaving no residual tumor. The tumor was diagnosed as a myxoid leiomyosarcoma that apparently originated in the greater omentum. A recurrent omental tumor was excised at 4.5 months after the first operation, and then at 5.5 months after this, CT revealed metastatic sarcoma at the surface of the liver (S7) and the left upper abdomen. She died 20 months after the last operation despite treatment of the metastases with MAID therapy (mesna, adriamycin, ifosfamide, dacarbazine). A literature review revealed that this tumor mainly occurs in the uterus, soft tissue, and cardiovascular system, with a preponderance among middle-aged to elderly women. The present report is the first description of primary omental myxoid leiomyosarcoma

Immunohistochemical and Lectin-Histochemical Patterns of Renal Non-Neoplastic and Neoplastic Epithelium: Utility of the Patterns in the Differential Diagnosis of Renal Epithelial Tumors

Renal tumors are considered to be composed of several distinct subtypes with different cell origin. In this study, we tried to find useful immunohistochemical and lectin histochemical patterns for the differential diagnosis and the origin of the tumor relative to the components of the nephron. Typical cases of clear cell carcinoma, granular cell carcinoma, chromophobe cell carcinoma, collecting-duct carcinoma, papillary carcinoma and oncocytoma, as well as sufficient margin of normal renal parenchyma were stained immunohistochemically and lectin-histochemically, using antibodies and lectins reported to show differences in reactivity. Non-neoplastic epithelial cells showed specific reactivity according to the nephron segments. Some of our staining results tended to differ from those reported earlier by other investigators. Neoplastic lesions showed specific immunoreactivities and the staining results were similar to those of the normal nephron segment, suggesting the origin of the respective tumors. Our results suggest that testing the immunoreactivity pattern using a panel of antibodies and lectins is useful for the differential diagnosis of renal neoplastic lesions

Immunohistochemical and Lectin-Histochemical Patterns of Renal Non-Neoplastic and Neoplastic Epithelium: Utility of the Patterns in the Differential Diagnosis of Renal Epithelial Tumors

Renal tumors are considered to be composed of several distinct subtypes with different cell origin. In this study, we tried to find useful immunohistochemical and lectin histochemical patterns for the differential diagnosis and the origin of the tumor relative to the components of the nephron. Typical cases of clear cell carcinoma, granular cell carcinoma, chromophobe cell carcinoma, collecting-duct carcinoma, papillary carcinoma and oncocytoma, as well as sufficient margin of normal renal parenchyma were stained immunohistochemically and lectin-histochemically, using antibodies and lectins reported to show differences in reactivity. Non-neoplastic epithelial cells showed specific reactivity according to the nephron segments. Some of our staining results tended to differ from those reported earlier by other investigators. Neoplastic lesions showed specific immunoreactivities and the staining results were similar to those of the normal nephron segment, suggesting the origin of the respective tumors. Our results suggest that testing the immunoreactivity pattern using a panel of antibodies and lectins is useful for the differential diagnosis of renal neoplastic lesions

Atypical Carcinoid Tumor of the Lung: Report of a Case with Intrapulmonary Metastasis

A 71-year-old man was noted to have a nodular opacity in S8 of the right lung. Thirteen months later, the chest CT showed a lesion "gloved finger shape " with focal calcification, and a small nodular opacity appeared in right S7. A right lower lobectomy was performed under video-assisted thoracic surgery. The tumor filled the S8 bronchus, with invasion into the pulmonary parenchyma and S7 metastasis. Mitotic figures were seen in 5 of 10 high power fields. Positive staining for chromogranin A and synaptophysin led to the diagnosis of atypical carcinoid. The patient has been disease-free without treatment for 9 months