214 research outputs found

    水質評価に用いるDO濃度が指標生物の分布に及ぼす影響様式の特定

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    Open House, ISM in Tachikawa, 2011.7.14統計数理研究所オープンハウス(立川)、H23.7.14ポスター発

    位置情報の決定要因分解によるマウス社会行動評価指針の考察

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    平成21年度研究報告会、統計数理研究所(広尾)、H22.3.18-19ポスター発

    水質管理指標としての閉鎖性海域底層DO濃度特性要約方針の策定

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    Open House, ISM in Tachikawa, 2010.7.9統計数理研究所オープンハウス(立川)、H22.7.9ポスター発

    Genetics of Endometrial Cancers

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    Endometrial cancers exhibit a different mechanism of tumorigenesis and progression depending on histopathological and clinical types. The most frequently altered gene in estrogen-dependent endometrioid endometrial carcinoma tumors is PTEN. Microsatellite instability is another important genetic event in this type of tumor. In contrast, p53 mutations or Her2/neu overexpression are more frequent in non-endometrioid tumors. On the other hand, it is possible that the clear cell type may arise from a unique pathway which appears similar to the ovarian clear cell carcinoma. K-ras mutations are detected in approximately 15%–30% of endometrioid carcinomas, are unrelated to the existence of endometrial hyperplasia. A β-catenin mutation was detected in about 20% of endometrioid carcinomas, but is rare in serous carcinoma. Telomere shortening is another important type of genomic instability observed in endometrial cancer. Only non-endometrioid endometrial carcinoma tumors were significantly associated with critical telomere shortening in the adjacent morphologically normal epithelium. Lynch syndrome, which is an autosomal dominantly inherited disorder of cancer susceptibility and is characterized by a MSH2/MSH6 protein complex deficiency, is associated with the development of non-endometrioid carcinomas

    Theory of Low Temperature Electron Spin Resonance in Half-integer Spin Antiferromagnetic Chains

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    A theory of low temperature (T) electron spin resonance (ESR) in half-integer spin antiferromagnetic chains is developed using field theory methods and avoiding previous approximations. It is compared to experiments on Cu benzoate. Power laws are predicted for the line-width broadening due to various types of anisotropy. At T -> 0, zero width absorption peaks occur in some cases. The second ESR peak in Cu benzoate, observed at T<.76K, is argued not to indicate Neel order as previously claimed, but to correspond to a sine-Gordon "breather" excitation.Comment: 4 pages, REVTEX, 3 PostScript figures embedded in tex
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