Relationship between Gender and Code Reading Speed in Software Development

Recently, workforce shortage has become a popular issue in information technology (IT). One solution to increasing the workforce supply is to increase the number of female IT professionals. This is because there is gender imbalance in information technology area. To accomplish this, it is important to suppress the influence of biases, such as the belief that men are more suited for careers in science and technology than women, and to increase the choice of careers available to female professionals. To help suppress the influence of gender bias, we analyzed the relationship between gender and code reading speed in the field of software development. Certain source codes require developers to use substantial memory to properly understand them, such as those with many variables that frequently change values. Several studies have indicated that the performance of memory differs in males and females. To test the veracity of this claim, we analyzed the influence of gender on code-reading speed through an experiment. Pursuant to this, we prepared four programs that required varied amounts of memory to properly understand them. Then, we measured the time required by each of the 17 male and 16 female subjects (33 subjects in total) to comprehend the different programs. The results suggest that there is no explicit difference between male and female subjects in this regard, even in the case of programs that require high memory capacities for proper understanding.Comment: Japanese letter version is available at: https://search.ieice.org/bin/summary.php?id=j104-d_5_521&category=D&year=2021&lang=J&abst

Visualization of oscillating flow in a double-inlet pulse tube refrigerator with a diaphragm inserted in a bypass-tube

The double-inlet pulse tube refrigerator that has a diaphragm inserted in a bypass-tube, which enabled it to transmit a pressure oscillation whereas to obstruct a DC gas flow, was manufactured and tested. The oscillating flow behavior inside of the refrigerator was studied by using a smoke-wire flow visualization technique. It was found that if the diaphragm was optimized, the performance would be improved more than that of the refrigerator with a bypass valve due to the increase in the PV work of the gas and the decrease in the convective heat loss caused by a secondary flow

Time-resolved study on signaling pathway of photoactivated adenylate cyclase and its nonlinear optical response

Photoactivated adenylate cyclases (PACs) are multidomain BLUF proteins that regulate the cellular levels of cyclic adenosine 3', 5'-monophosphate (cAMP) in a light-dependent manner. The signaling route and dynamics of PAC from Oscillatoria acuminata (OaPAC), which consists of a light sensor BLUF domain, an adenylate cyclase domain, and a connector helix (α3-helix), were studied by detecting conformational changes in the protein moiety. Although circular dichroism and small-angle X-ray scattering measurements did not show significant changes upon light illumination, the transient grating method successfully detected light-induced changes in the diffusion coefficient (diffusion-sensitive conformational change (DSCC)) of full-length OaPAC (FL-PAC) and the BLUF domain with the α3-helix. DSCC of FL-PAC was observed only when both protomers in a dimer were photoconverted. This light intensity dependence suggests that OaPAC is a cyclase with a nonlinear light intensity response. The enzymatic activity indeed nonlinearly depends on light intensity, that is, OaPAC is activated under strong light conditions. It was also found that both DSCC and enzymatic activity were suppressed by a mutation in the W90 residue, indicating the importance of the highly conserved Trp in many BLUF domains for the function. Based on these findings, a reaction scheme was proposed together with the reaction dynamics

Ski jumping flight skill analysis based on high-speed video image

AbstractMages of the initial 40 m part of a flight of 120-m ski jumping were recorded by a fixed high-speed video camera in Hakuba Ski Jumping Stadium. The time variations of the forward leaning angle and the ski angle of attack were measured from the video image and the aerodynamic forces were calculated from kinematic data. Some correlations were investigated between the reduced jumping distance Dr, which is an initial speed corrected flight distance, and some key angles and the initial transition time, as well as those between Dr and the aerodynamic force coefficients. Jumping performance is compared between advanced jumpers and beginner jumpers

Flight Performance of the AKARI Cryogenic System

We describe the flight performance of the cryogenic system of the infrared astronomical satellite AKARI, which was successfully launched on 2006 February 21 (UT). AKARI carries a 68.5 cm telescope together with two focal plane instruments, Infrared Cameras (IRC) and Far Infrared Surveyor (FIS), all of which are cooled down to cryogenic temperature to achieve superior sensitivity. The AKARI cryogenic system is a unique hybrid system, which consists of cryogen (liquid helium) and mechanical coolers (2-stage Stirling coolers). With the help of the mechanical coolers, 179 L (26.0 kg) of super-fluid liquid helium can keep the instruments cryogenically cooled for more than 500 days. The on-orbit performance of the AKARI cryogenics is consistent with the design and pre-flight test, and the boil-off gas flow rate is as small as 0.32 mg/s. We observed the increase of the major axis of the AKARI orbit, which can be explained by the thrust due to thermal pressure of vented helium gas.Comment: 19 pages, 10 figures, and 6 tables. Accepted for publication in the AKARI special issue of the Publications of the Astronomical Society of Japa

Voxel‐based specific regional analysis system for Alzheimer’s disease utility as a screening tool for unrecognized cognitive dysfunction of elderly patients in diabetes outpatient clinics: Multicenter retrospective exploratory study

AIMS/INTRODUCTION: An efficient screening strategy for identification of cognitive dysfunction remains a clinical issue in the management of elderly adults with diabetes. A magnetic resonance imaging voxel-based specific regional analysis system for Alzheimer's disease (VSRAD) has been developed as an automated brain morphometry system that includes the hippocampus. We carried out a multicenter retrospective study to evaluate the utility of VSRAD for screening cognitive dysfunction in diabetes outpatient clinics. MATERIALS AND METHODS: We enrolled patients with diabetes aged >65 years who underwent brain magnetic resonance imaging scans for the purpose of a medical checkup between November 2018 and May 2019. Patients who were already suspected or diagnosed with mild cognitive impairment and/or dementia as well as those with a history of cerebrovascular disease were excluded. RESULTS: A total of 67 patients were enrolled. Five patients were diagnosed with mild cognitive impairment or dementia (clinical cognitive dysfunction). Patients with clinical cognitive dysfunction showed a significantly higher z-score in VSRAD analysis (2.57 ± 0.47 vs 1.15 ± 0.55, P < 0.01). The sensitivities and specificities for diagnosis of clinical cognitive dysfunction were 80 and 48% for the Mini-Mental State Examination, 100 and 89% for the z-score, and 100 and 90% for the combination of the Mini-Mental State Examination score and z-score, respectively. CONCLUSIONS: VSRAD analysis can distinguish patients with clinical cognitive dysfunction in the elderly with diabetes, and also shows reasonable sensitivity and specificity compared with the Mini-Mental State Examination alone. Thus, VSRAD analysis can be useful for early identification of clinical cognitive dysfunction in the elderly with diabetes

CD73-generated adenosine restricts lymphocyte migration into draining lymph nodes.

After an inflammatory stimulus, lymphocyte migration into draining lymph nodes increases dramatically to facilitate the encounter of naive T cells with Ag-loaded dendritic cells. In this study, we show that CD73 (ecto-5\u27-nucleotidase) plays an important role in regulating this process. CD73 produces adenosine from AMP and is expressed on high endothelial venules (HEV) and subsets of lymphocytes. Cd73(-/-) mice have normal sized lymphoid organs in the steady state, but approximately 1.5-fold larger draining lymph nodes and 2.5-fold increased rates of L-selectin-dependent lymphocyte migration from the blood through HEV compared with wild-type mice 24 h after LPS administration. Migration rates of cd73(+/+) and cd73(-/-) lymphocytes into lymph nodes of wild-type mice are equal, suggesting that it is CD73 on HEV that regulates lymphocyte migration into draining lymph nodes. The A(2B) receptor is a likely target of CD73-generated adenosine, because it is the only adenosine receptor expressed on the HEV-like cell line KOP2.16 and it is up-regulated by TNF-alpha. Furthermore, increased lymphocyte migration into draining lymph nodes of cd73(-/-) mice is largely normalized by pretreatment with the selective A(2B) receptor agonist BAY 60-6583. Adenosine receptor signaling to restrict lymphocyte migration across HEV may be an important mechanism to control the magnitude of an inflammatory response

The Volume Conjecture, Perturbative Knot Invariants, and Recursion Relations for Topological Strings

We study the relation between perturbative knot invariants and the free energies defined by topological string theory on the character variety of the knot. Such a correspondence between SL(2;C) Chern-Simons gauge theory and the topological open string theory was proposed earlier on the basis of the volume conjecture and AJ conjecture. In this paper we discuss this correspondence beyond the subleading order in the perturbative expansion on both sides. In the computation of the perturbative invariants for the hyperbolic 3-manifold, we adopt the state integral model for the hyperbolic knots, and the factorized AJ conjecture for the torus knots. On the other hand, we iteratively compute the free energies on the character variety using the Eynard-Orantin topological recursion relation. We check the correspondence for the figure eight knot complement and the once punctured torus bundle over S^1 with the holonomy L^2R up to the fourth order. For the torus knots, we find trivial the recursion relations on both sides.Comment: 48 pages, 7 figure

The efficacy of enteral nutrition for patients who had complications after gastrectomy for gastric cancer

When nutritional supports are needed, enteral nutrition （EN） is recommended since it is more physiologic and effective compared with parental nutrition. However, the efficacy and safety of EN remains unclear for patients who had complications after gastrectomy for gastric cancer. In the current study, 4 patients took EN and 10 patients took total parental nutrition （TPN） due to complications after gastrectomy for gastric cancer from 2012 to 2014. In the EN group, tube was placed through the nose into the small bowel using nasal endoscope and guide wire without any complications. Total calorie given in EN group was significantly higher than that in TPN group （p=0.005）. The rates of increase in serum concentration of total protein and albumin in EN group was higher than those in TPN group although there was not significant difference. Furthermore, postoperative length of hospital stay in EN group was shorter than that in TPN group without significant differences. There is no complication attributed to EN while there are three catheter-related bloodstream infection in the TPN group. Our results indicate that EN is effective and safe for patients who had complications after gastrectomy for gastric cancer