COVID-19 and Substance Use Disorders:Recommendations to a Comprehensive Healthcare Response. An International Society of Addiction Medicine (ISAM) Practice and Policy Interest Group Position Paper

Coronavirus disease 2019 (COVID-19) is escalating all over the world and has higher morbidities and mortalities in certain vulnerable populations. People Who Use Drugs (PWUD) are a marginalized and stigmatized group with weaker immunity responses, vulnerability to stress, poor health conditions, high-risk behaviors, and lower access to health care services. These conditions put them at a higher risk of COVID-19 infection and its complications. In this paper, an international group of experts on addiction medicine, infectious diseases, and disaster psychiatry explore the possible raised concerns in this issue and provide recommendations to manage the comorbidity of COVID-19 and Substance Use Disorder (SUD).Publisher PDFPeer reviewe

The effects of hypoxia on cyclooxygenase-2 expression and eicosanoid synthesis / by Maryanne Demasi.

Includes list of publications arising from this thesisErratum attached to inside back cover."25/03/2004."Includes bibliographical references (leaves 185-257)xii, 257 leaves : ill. ; 30 cm.Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine and Royal Adelaide Hospital, Rheumatology Unit, 200

Especialistas ponderam após processar a FDA por acesso aos dados do teste da Pfizer

Considerações éticas sobre o processo da FDA por acesso aos dados do teste da Pfize

Three Technologies That Will Change the Way We Live

Adelaide Festival of Ideas session, RiAus Auditorium, 12:00pm, Saturday 8th October, 2011. This session is presented by RiAus and Bridge8 for the National Enabling Technologies Strategy Expert Forum and the Department of Innovation, Industry, Science and Research, and facilitated by Maryanne Demasi. There are emerging radical technologies that have the potential to change the way we live. In this session we’ll explore the contribution of enabling bio- and nano-technologies and their associated socio-cultural, health, safety and environmental impacts. We’ll ask what excites you about this? What scares you? And use foresight approaches to explore how they may change the way we live, and how we might all manage such rapid and transformative changes.http://adelaidefestivalofideas.com.a

Biochemical effects of a diet containing foods enriched with n-3 fatty acids1-3

BackgroundResults of many studies indicate that consumption of n-3 fatty acids can benefit persons with cardiovascular disease and rheumatoid arthritis. However, encapsulated fish oil is unlikely to be suited to lifetime daily use and recommendations to increase fish intake have not been effective.ObjectiveThe objective was to examine the effectiveness of a diet that incorporates foods rich in n-3 fatty acids in elevating tissue concentrations of eicosapentaenoic acid and in suppressing the production of inflammatory mediators.DesignHealthy male volunteers were provided with foods that were enriched in alpha-linolenic acid (cooking oil, margarine, salad dressing, and mayonnaise) and eicosapentaenoic and docosahexaenoic acids (sausages and savory dip) and with foods naturally rich in n-3 fatty acids, such as flaxseed meal and fish. Subjects incorporated these products into their food at home for 4 wk. Fatty acid intakes, cellular and plasma fatty acid concentrations, and monocyte-derived eicosanoid and cytokine production were measured.ResultsAnalyses of dietary records indicated that intake of eicosapentaenoic acid plus docosahexaenoic acid averaged 1.8 g/d and intake of alpha-linolenic acid averaged 9. 0 g/d. These intakes led to an average 3-fold increase in eicosapentaenoic acid in plasma, platelet, and mononuclear cell phospholipids. Thromboxane B(2), prostaglandin E(2), and interleukin 1beta synthesis decreased by 36%, 26%, and 20% (P ConclusionsFoods that are strategically or naturally enriched in n-3 fatty acids can be used to achieve desired biochemical effects without the ingestion of supplements or a change in dietary habits. A wide range of n-3-enriched foods could be developed to support large-scale programs on the basis of the therapeutic and disease-preventive effects of n-3 fatty acids.Evangeline Mantzioris, Leslie G Cleland, Robert A Gibson, Mark A Neumann, Maryanne Demasi, and Michael J Jame