Genetic frequency distribution.

<p>Genetic frequency distribution.</p

A novel single nucleotide polymorphism in exon 3 of <i>MYOC</i> enhances the risk of glaucoma - Fig 1

<p>(a,b). Location and map of LDofSNPs onchromosome 1. The SNP numbers are represented at the top of the haploview. The pair-wise LD coefficient (r²) is presented at the top, and LD^* = D’.</p

Allelic frequency distribution.

<p>Allelic frequency distribution.</p

Safety and efficacy of hydroxychloroquine in COVID-19: a systematic review and meta-analysis

Background: During the initial phases of the coronavirus disease 2019 (COVID-19) epidemic, there was an unfounded fervor surrounding the use of hydroxychloroquine (HCQ); however, recently, the Centers for Disease Control and Prevention (CDC) has recommended against routine use of HCQ outside of study protocols citing possible adverse outcomes.Methods: Multiple databases were searched to identify articles on COVID-19. An unadjusted odds ratio (OR) was used to calculate the safety and efficacy of HCQ on a random effect model.Results: Twelve studies comprising 3,912 patients (HCQ 2,512 and control 1400) were included. The odds of all-cause mortality (OR: 2.23, 95% confidence interval (CI): 1.58 - 3.13, P value Conclusions: HCQ might offer no benefits in terms of decreasing the viral load and radiological improvement in patients with COVID-19. HCQ appears to be associated with higher odds of all-cause mortality and NAEs.</div