Differences in diet quality and socioeconomic patterning of diet quality across ethnic groups: cross-sectional data from the HELIUS Dietary Patterns study

Funder: British Heart Foundation (BHF); doi: https://doi.org/10.13039/501100000274Funder: RCUK | Economic and Social Research Council (ESRC); doi: https://doi.org/10.13039/501100000269Funder: DH | National Institute for Health Research (NIHR); doi: https://doi.org/10.13039/501100000272Funder: Wellcome Trust (Wellcome); doi: https://doi.org/10.13039/100004440Funder: RCUK | Medical Research Council (MRC); doi: https://doi.org/10.13039/501100000265Funder: Netherlands Organization for Health Research and DevelopmentAbstract: Background/objectives: Socioeconomic inequalities in diet quality are consistently reported, but few studies have investigated whether and how such inequalities vary across ethnic groups. This study aimed to examine differences in diet quality and socioeconomic patterning of diet quality across ethnic groups. Subjects/methods: Cross-sectional data from the HELIUS study were used. Dutch, South-Asian Surinamese, African Surinamese, Ghanaian, Turkish and Moroccan adults (aged 18–70 years) were randomly sampled, stratified by ethnicity. Dietary intake was estimated among a subsample (n = 4602) from 200-item, ethnic-specific food frequency questionnaires, and diet quality was assessed using the Dutch Healthy Diet Index 2015 (DHD15-Index). Wald tests were used to compare non-Dutch and Dutch participants. Adjusted linear regression models were used to examine differences in DHD15-Index by three indicators of socioeconomic position: educational level, occupational status and perceived financial difficulties. All analyses were stratified by sex. Results: Dutch participants had lower median DHD15-Index than most ethnic minority participants (P < 0.001). Lower educational level was associated with lower DHD15-Index among Dutch men (Ptrend < 0.0001), South-Asian Surinamese men (Ptrend = 0.01), Dutch women (Ptrend = 0.0001), African Surinamese women (Ptrend = 0.002) and Moroccan women (Ptrend = 0.04). Lower occupational status was associated with lower DHD15-Index in Dutch men, β −7.8 (95% CI −11.7, −3.9) and all women (β −4.4 to −8.8), except Turkish women. DHD15-Index was not associated with perceived financial difficulties in most groups. Conclusions: We observed variations in diet quality across ethnic groups. Low socioeconomic position was not consistently associated with poor diet quality in all ethnic groups. This may be due to ethnicity-specific retention of traditional diets, irrespective of socioeconomic position

Ariel - Volume 12 Number 1

Executive Editors David G. Polin Larry H. Pastor Business Manager Alex Macones Jean Lien Editorial Page Editor Sam Markind Photography Editors Ken Yonemura Lois Leach Sports Editor Todd Hoove

Simulation expérimentale de l'usure du contact aube-disque de compresseur sous sollicitations de fretting

Lors du fonctionnement d'un turboréacteur, la rotation de l'axe du moteur induit une force centrifuge qui plaque les aubes contre les alvéoles du disque, le long de surfaces appelées portées . Au cours de la vie du moteur, des micro-glissements ( fretting ) sont générés au niveau des portées. Ce travail de thèse s'intéresse aux endommagements de type oligocyclique des portées aube/ disque du compresseur Haute Pression (HP) d'un turboréacteur civil. Afin de réduire le frottement et de protéger les pièces, les portées des aubes sont revêtues d'un dépôt épais de CuNiln sur lequel est appliqué un lubrifiant solide. Le système est soumis à des pressions fortes (600MPa) et à des températures élevées (500C). Des expertises sur pièces ont permis d'identifier des usures importantes et des phénomènes de transfert. Pour simuler expérimentalement le contact, un moyen d'essai de fretting usure en température a été développé dans le cadre de cette thèse. A partir d'une géométrie de contact échelle 1 simplifiée, choisie pour représenter les champs de chargement moteur, le domaine des sollicitations a été balayé et les comportements tribologiques identifiés et caractérisés. L'étude tribologique a permis de mettre en évidence l'influence forte de la force normale sur les mécanismes d'endommagements, dont les scénarios de mise en place ont pu être explicités pour les deux domaines majeurs de sollicitations. Dans un deuxième temps, les endommagements ont été étudiés d'un point de vue physicochimique et le rôle tribochimique joué par les éléments environnementaux (0, N ... ) a été mis en évidence. Pour finir, la comparaison directe des mécanismes identifiés sur banc expérimental et sur le système industriel a permis d'aborder, d'un point de vue critique, l'importance des paramètres choisis pour les équivalences expérience / système industriel ; et de la dynamique de chargement pour garantir la représentativité d'un essai à l'échelle laboratoire.In the blade/ disk contact of aero-engines, movements induced by the engine regime changes may lead to critical wear. In order to limit friction and protect components, motorists usually use a thick and soft CuNiin layer (150 !-lm) covered with a lubricant. This system is subjected to high contact pressure (upto 600 MPa) and high temperatures (up to 500 C). In service observations of engine parts revealed significant wear and transfer phenomena. An experimental layout was designed to perform fretting wear tests in temperature on a punch/plane contact, representative of engine solicitation. Based on the tribological study performed, specified gradation mechanisms were identified and the evidence of a pressure threshold was demonstrated. Physicochemical analyses performed confirmed the role played by environment (0, N ... ) in fretting wear mechanisms and suggest that the tribochemical effects should be considered in the fretting wear models. Direct comparisons between degradation mechanisms identified on the experimental system, and on industrial parts, allow a critical review of parameters chosen to simulate the contact. Finally, the impact of loading dynamics was investigated in order to improve tests representativity at la bora tory scale.LYON-Ecole Centrale (690812301) / SudocSudocFranceF

Brucella abortus Infection of Placental Trophoblasts Triggers Endoplasmic Reticulum Stress-Mediated Cell Death and Fetal Loss via Type IV Secretion System-Dependent Activation of CHOP.

Subversion of endoplasmic reticulum (ER) function is a feature shared by multiple intracellular bacteria and viruses, and in many cases this disruption of cellular function activates pathways of the unfolded protein response (UPR). In the case of infection with Brucella abortus, the etiologic agent of brucellosis, the unfolded protein response in the infected placenta contributes to placentitis and abortion, leading to pathogen transmission. Here we show that B. abortus infection of pregnant mice led to death of infected placental trophoblasts in a manner that depended on the VirB type IV secretion system (T4SS) and its effector VceC. The trophoblast death program required the ER stress-induced transcription factor CHOP. While NOD1/NOD2 expression in macrophages contributed to ER stress-induced inflammation, these receptors did not play a role in trophoblast death. Both placentitis and abortion were independent of apoptosis-associated Speck-like protein containing a caspase activation and recruitment domain (ASC). These studies show that B. abortus uses its T4SS to induce cell-type-specific responses to ER stress in trophoblasts that trigger placental inflammation and abortion. Our results suggest further that in B. abortus the T4SS and its effectors are under selection as bacterial transmission factors.IMPORTANCE Brucella abortus infects the placenta of pregnant cows, where it replicates to high levels and triggers abortion of the calf. The aborted material is highly infectious and transmits infection to both cows and humans, but very little is known about how B. abortus causes abortion. By studying this infection in pregnant mice, we discovered that B. abortus kills trophoblasts, which are important cells for maintaining pregnancy. This killing required an injected bacterial protein (VceC) that triggered an endoplasmic reticulum (ER) stress response in the trophoblast. By inhibiting ER stress or infecting mice that lack CHOP, a protein induced by ER stress, we could prevent death of trophoblasts, reduce inflammation, and increase the viability of the pups. Our results suggest that B. abortus injects VceC into placental trophoblasts to promote its transmission by abortion

Interobserver Variation Study of the Rutgeerts Score to Assess Endoscopic Recurrence after Surgery for Crohn's Disease.

BACKGROUND: After resection surgery for Crohn's disease, recurrence of endoscopic lesions at the site of the anastomosis or in the neoterminal ileum is graded according to the Rutgeerts score (RS). The goal of this study was to test the interobserver variability for RS. METHODS: Thirteen trained endoscopists evaluated the RS on 39 videotapes of patients who had undergone resection for Crohn's disease with an ileocolonic anastomosis 6 months earlier. Videotapes were randomly assigned to endoscopists through a balanced incomplete block design. Each videotape was scored independently by four endoscopists, and each endoscopist evaluated 12 videotapes, making a total of 156 videotape assessments. Reproducibility levels of the RS were assessed through unweighted kappa estimates among multiple raters. The proportion of inappropriate therapeutic initiation was estimated by randomly selecting one endoscopist for each videorecording, assuming that the majority of endoscopists correctly classified endoscopic recurrence. RESULTS: The kappa estimates were 0.43 (95% confidence interval: 0.33-0.52) for the RS on a 5-grade scale, 0.47 (0.28-0.66) for RS /= i2, and 0.64 (0.42-0.85) for RS i2. The percentages of inappropriate therapeutic initiation were 12.8% (3.8-21.9) when initiation was triggered by a RS >/= i2 and 8.3% (1.1-15.6) when initiation was triggered by a RS > i2 (p = 0.41). CONCLUSION: The reproducibility of the RS was moderate, especially when differentiating /=i2, which may lead to incorrect therapeutic decisions in >10% of patients

The Grizzly, October 15, 1982

Students for Peace and Progress Get Started • Homecoming 1982 • Annual Parents Day a Success • Letters to the Editor • Opinion: Sorority Rushing Needs Revision • Lantern Format Undecided • Dance-a-Thon for Lupus • Japan: Big and Real • New Art at Myrin • Bear Booters Win Three • Now Hold it Just a Minute! • Grizzlies Win Third Straight • X-Country Wins • Penn Blasts Lady Bears 3-0https://digitalcommons.ursinus.edu/grizzlynews/1084/thumbnail.jp

The Vehicle, 1961, Vol. 3 no. 2

Vol. 3, No. 2 Table of Contents The Voting CattleLinda Kay Campbellpage 5 But For the Passage of TimeDon Shepardsonpage 14 LoveJon Woodspage 16 Infinite JourneyJames E. Martinpage 19 The Clover ChainRichard W. Blairpage 20 SnowballSusan Daughertypage 24 Sureness Is NeverDon Shepardsonpage 26 ConceptionChristine McCollpage 34 Comedy: Relief and GriefTom McPeakpage 35 The Unspoken WordChristine McCollpage 35 CharmBenjamin Polkpage 36 Screaming SpiderTom McPeakpage 39 Just Once in an Early SpringE.J.B.page 39 HummingbirdPauline B. Smithpage 40 Willow TreesPauline B. Smithpage 40 MaturityChristine McCollpage 41 The New YearLinda Campbellpage 41 The StormMary-Jean Pitratpage 42 Ebony IvoryJean Danenbargerpage 42 The Fireball MailAllen Engelbrightpage 43 ExpectationChristine McCollpage 44 CatastropheChristine McCollpage 44 SophisticationBenjamin Polkpage 45 On Playing BridgeMyrna Jo Handleypage 46 SonnetMignon Stricklandpage 48https://thekeep.eiu.edu/vehicle/1009/thumbnail.jp

The Vehicle, 1961, Vol. 3 no. 2

Vol. 3, No. 2 Table of Contents The Voting CattleLinda Kay Campbellpage 5 But For the Passage of TimeDon Shepardsonpage 14 LoveJon Woodspage 16 Infinite JourneyJames E. Martinpage 19 The Clover ChainRichard W. Blairpage 20 SnowballSusan Daughertypage 24 Sureness Is NeverDon Shepardsonpage 26 ConceptionChristine McCollpage 34 Comedy: Relief and GriefTom McPeakpage 35 The Unspoken WordChristine McCollpage 35 CharmBenjamin Polkpage 36 Screaming SpiderTom McPeakpage 39 Just Once in an Early SpringE.J.B.page 39 HummingbirdPauline B. Smithpage 40 Willow TreesPauline B. Smithpage 40 MaturityChristine McCollpage 41 The New YearLinda Campbellpage 41 The StormMary-Jean Pitratpage 42 Ebony IvoryJean Danenbargerpage 42 The Fireball MailAllen Engelbrightpage 43 ExpectationChristine McCollpage 44 CatastropheChristine McCollpage 44 SophisticationBenjamin Polkpage 45 On Playing BridgeMyrna Jo Handleypage 46 SonnetMignon Stricklandpage 48https://thekeep.eiu.edu/vehicle/1009/thumbnail.jp