Additional file 1: of Comparison of methods to assess onset of breast development in the LEGACY Girls Study: methodological considerations for studies of breast cancer

Table S1. Study characteristics in the cohort and subsets. (DOCX 14 kb

Additional file 1: Figure S1A. of Non-invasive optical spectroscopic monitoring of breast development during puberty

OS instrument with an image of the source and detector on a forearm. Figure S1B. Template allowing source detector placement. Figure S1C. Absorption spectra provided by the five dominant absorbers in breast tissue, collagen (black solid line), lipid (black dashed line), water (black dotted line), hemoglobin (gray solid line) and oxyhemoglobin (gray dotted line). Figure S2A. PC1 (black solid line), PC2 (blue dashed line), PC3 (red dashed-dotted line) and PC4 (green dotted line). Figure S2B. PC5 (black solid line), PC6 (blue dashed line), PC7 (red dashed-dotted line) and PC8 (green dotted line). Figure S3A. Predictors of TS1–TS4. Figure S3B. Predictors of early (TS1–TS2) and late (TS3–TS5) pubertal stages. Figure S4A. Random forest feature selection for a classifier of TS1–TS4. Figure S4B. Random forest feature selection for a classifier of early (TS1–TS2) and late (TS3–TS5). Figure S5. BCRS against predictor variables. (PDF 6282 kb

Additional file 1: Table S1. of Pubertal development in girls by breast cancer family history: the LEGACY girls cohort

Associations of measures of breast cancer family history (BCFH) with age at onset and pubertal tempo. (DOCX 14 kb

Additional file 2: Figure S1. of Pubertal development in girls by breast cancer family history: the LEGACY girls cohort

Mean BMI z scores and 95% confidence intervals stratified by age group, breast Tanner stage, and breast cancer family history (BCFH). (PDF 217 kb

Additional file 2: of Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2

List of local ethics committees that granted approval for the access and use of the data in present study. (DOCX 23 kb

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原著和名: [記載なし]科名: = unknown採集地: タイ カオヤイ国立公園 (タイ国 カオヤイ国立公園)採集日: 1984/10/13採集者: 萩庭丈壽整理番号: JH051286国立科学博物館整理番号: TNS-VS-94871