Severe asthma disease duration and inflammation related to abundance of <i>Haemophilus., Streptococcus</i>, and <i>Moraxella sp.</i>

<p>The relationship in treatment-resistant severe asthma between total abundance of <i>Haemophilus sp., Streptococcus sp.</i>, and <i>Moraxella catarrhalis</i> in induced sputum samples and [A] neutrophil differential cell count (%), [B] asthma duration (years), [C] interleukin (IL)-8 concentration in induced sputum and [D] the relationship between <i>M. catarrhalis</i> abundance and induced sputum IL-8 concentration.</p

Interleukin-8 sputum supernatant concentrations in severe asthma related to sputum neutrophil count and lung function.

<p>The relationship in treatment-resistant severe asthma between IL-8 concentrations in induced sputum and (A) neutrophil differential cell counts and (B) Post bronchodilator percent predicted FEV₁.</p