119 research outputs found
Predation by Insidious Flower Bug, Orius insidiosus, Adults on Western Flower Thrips, Frankliniella occidentalis, Adults under Laboratory and Greenhouse Conditions
Get PDFWestern flower thrips, Frankliniella occidentalis (Perg.), is a major insect pest of greenhouse production systems. A widely-used plant protection strategy is biological control, which entails releasing natural enemies; such as parasitoids and predators, that are commercially available from suppliers or distributors. Studies to assess predation of predatory mites and predatory bugs against specific prey are typically conducted under laboratory conditions. However, results obtained under laboratory conditions may not be equivalent to results observed under field conditions; including greenhouses when plants are present. Therefore, the goal of our study was to compare predation by insidious flower bug, Orius insidiosus Say, adults under laboratory and greenhouse conditions to determine if flower morphology of transvaal daisy, Gerbera jamesonii, cut flowers affects predation by adult insidious flower bugs on western flower thrips adults
Progranulin Loss Results in Sex-Dependent Dysregulation of the Peripheral and Central Immune System
Get PDFINTRODUCTION: Progranulin (PGRN) is a secreted glycoprotein, the expression of which is linked to several neurodegenerative diseases. Although its specific function is still unclear, several studies have linked it with lysosomal functions and immune system regulation. Here, we have explored the role of PGRN in peripheral and central immune system homeostasis by investigating the consequences of PGRN deficiency on adaptive and innate immune cell populations.
METHODS: First, we used gene co-expression network analysis of published data to test the hypothesis that
RESULTS: Male PGRN KO mice exhibited a lower abundance of microglial cells with higher MHC-II expression, increased CD44 expression on monocytes in the brain, and more CNS-associated CD8
DISCUSSION: Our data suggest that PGRN and GPNMB jointly regulate the peripheral and the central immune system in a sex-specific manner; thus, understanding their associated mechanisms could pave the way for developing new neuroprotective strategies to modulate central and peripheral inflammation to lower risk for neurodegenerative diseases and possibly delay or halt progression
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