22 research outputs found
CATALISE: A multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
© 2016 Bishop et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Delayed or impaired language development is a common developmental concern, yet there is little agreement about the criteria used to identify and classify language impairments in children. Children\u27s language difficulties are at the interface between education, medicine and the allied professions, who may all adopt different approaches to conceptualising them. Our goal in this study was to use an online Delphi technique to see whether it was possible to achieve consensus among professionals on appropriate criteria for identifying children who might benefit from specialist services. We recruited a panel of 59 experts representing ten disciplines (including education, psychology, speech-language therapy/pathology, paediatrics and child psychiatry) from English-speaking countries (Australia, Canada, Ireland, New Zealand, United Kingdom and USA). The starting point for round 1 was a set of 46 statements based on articles and commentaries in a special issue of a journal focusing on this topic. Panel members rated each statement for both relevance and validity on a sevenpoint scale, and added free text comments. These responses were synthesised by the first two authors, who then removed, combined or modified items with a view to improving consensus. The resulting set of statements was returned to the panel for a second evaluation (round 2). Consensus (percentage reporting \u27agree\u27 or \u27strongly agree\u27) was at least 80 percent for 24 of 27 round 2 statements, though many respondents qualified their response with written comments. These were again synthesised by the first two authors. The resulting consensus statement is reported here, with additional summary of relevant evidence, and a concluding commentary on residual disagreements and gaps in the evidence base
Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting
This manuscript provides nomenclature recommendations developed by an international workgroup to increase transparency and standardization of pharmacogenetic (PGx) result reporting. Presently, sequence variants identified by PGx tests are described using different nomenclature systems. In addition, PGx analysis may detect different sets of variants for each gene, which can affect interpretation of results. This practice has caused confusion and may thereby impede the adoption of clinical PGx testing. Standardization is critical to move PGx forward
CATALISE: A multinational and multidisciplinary Delphi consensus study. Identifying language impairments in children
Delayed or impaired language development is a common developmental concern, yet thereis little agreement about the criteria used to identify and classify language impairments inchildren. Children's language difficulties are at the interface between education, medicineand the allied professions, who may all adopt different approaches to conceptualising them.Our goal in this study was to use an online Delphi technique to see whether it was possibleto achieve consensus among professionals on appropriate criteria for identifying childrenwho might benefit from specialist services. We recruited a panel of 59 experts representingten disciplines (including education, psychology, speech-language therapy/pathology, paediatricsand child psychiatry) from English-speaking countries (Australia, Canada, Ireland,New Zealand, United Kingdom and USA). The starting point for round 1 was a set of 46statements based on articles and commentaries in a special issue of a journal focusing onthis topic. Panel members rated each statement for both relevance and validity on a sevenpointscale, and added free text comments. These responses were synthesised by the firsttwo authors, who then removed, combined or modified items with a view to improving consensus.The resulting set of statements was returned to the panel for a second evaluation(round 2). Consensus (percentage reporting 'agree' or 'strongly agree') was at least 80 percentfor 24 of 27 round 2 statements, though many respondents qualified their responsewith written comments. These were again synthesised by the first two authors. The resultingconsensus statement is reported here, with additional summary of relevant evidence, and aconcluding commentary on residual disagreements and gaps in the evidence base.</p
Phase 2 of CATALISE: a multinational and multidisciplinary Delphi consensus study of problems with language development: Terminology.
Background: Lack
of agreement about criteria and terminology for children’s language problems
affects access to services as well as hindering research and practice. We
report the second phase of a study using an online Delphi method to address
these issues. In the first phase, we focused on criteria for language disorder.
Here we consider terminology.Methods: The Delphi
method is an iterative process in which an initial set of statements is rated
by a panel of experts, who then have the opportunity to view anonymised ratings
from other panel members. On this basis they can either revise their views or
make a case for their position. The statements are then revised based on panel feedback,
and again rated by and commented on by the panel. In this study, feedback from
a second round was used to prepare a final set of statements in narrative form.
The panel included 57 individuals representing a range of professions and
nationalities. Results: We achieved
at least 78% agreement for 19 of 21 statements within two rounds of ratings.
These were collapsed into 12 statements for the final consensus reported here.
The term ‘Language Disorder’ is recommended to refer to a profile of
difficulties that causes functional impairment in everyday life and is associated
with poor prognosis. The term, ‘Developmental Language Disorder’ (DLD) was
endorsed for use when the language disorder was not associated with a known
biomedical aetiology. It was also agreed that (a) presence of risk factors
(neurobiological or environmental) does not preclude a diagnosis of DLD, (b)
DLD can co-occur with other neurodevelopmental disorders (e.g. ADHD) and (c)
DLD does not require a mismatch between verbal and nonverbal ability. Conclusions:
This Delphi exercise highlights reasons for disagreements about
terminology for language disorders and proposes standard definitions and
nomenclature.
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Memorial Hour: Rachel L. Bodley.
Papers read at the Memorial Hour commemorative of the late Prof. Rachel L. Bodley