Impact of implementing constructed wetlands on supporting the sustainable development goals

The United Nations Sustainable Development Goals’ (UN SDGs) action call promotes worldwide social, environmental, and economic prosperity. Each country developed a local plan to achieve the SDGs’ objectives and targets. The UN presents an annual global SDG progress report, based on an international indicator framework and regional available data. Wetland ecosystems contribute to the SDGs; however, more research is required to evaluate wetlands’ impact on sustainable development. This study investigates how implementing constructed wetlands (CW) at a local scale can contribute to achieving and promoting the SDGs with application in Kuwait. A preliminary design of a constructed wetlands wastewater treatment system is proposed alongside a local scoring framework based on regional information to assess the future projection of the SDGs in Kuwait. Overall, CW implementation plans contributed positively to improving the level of achievement of SDG 2: Zero Hunger, SDG 3: Good Health, SDG 6: Clean Water, SDG 7: Affordable and Clean Energy, and SDG 15: Life on Land. The analysis also highlights synergies that need to be considered for integrated environmental governance and enhanced policy coherence for Kuwait’s sustainable development management

Razvoj i validacija spektrofotometrijskih metoda za određivanje ceftazidima u farmaceutskim doziranim pripravcima

Two spectrophotometric methods for the determination of ceftazidime (CFZM) in either pure form or in its pharmaceutical formulations are described. The first method is based on the reaction of 3-methylbenzothiazolin-2-one hydrazone (MBTH) with ceftazidime in the presence of ferric chloride in acidic medium. The resulting blue complex absorbs at λmax 628 nm. The second method describes the reaction between the diazotized drug and N-(1-naphthyl)ethylenediamine dihydrochloride (NEDA) to yield a purple colored product with λmax at 567 nm. The reaction conditions were optimized to obtain maximum color intensity. The absorbance was found to increase linearly with increasing the concentration of CFZM; the systems obeyed the Beer’s law in the range 210 and 1050 µg mL1 for MBTH and NEDA methods, respectively. LOD, LOQ and correlation coefficient values were 0.15, 0.79 and 0.50, 2.61. No interference was observed from common excipients present in pharmaceutical formulations. The proposed methods are simple, sensitive, accurate and suitable for quality control applications.Razvijene su dvije spektrofotometrijske metode za određivanje ceftazidima (CFZM), čistog ili u farmaceutskim pripravcima. Prva metoda se temelji na reakciji 3-metilbenzotiazolin-2-on hidrazona (MBTH) sa ceftazidimom u prisutnosti željezovog(III) klorida u kiselom mediju. Nastaje plavi kompleks s maksimumom apsorpcije pri λmax 628 nm. Druga metoda se temelji na reakciji između diazotiranog lijeka i N-(1-naftil)etilendiamin dihidroklorida (NEDA), pri čemu nastaje ljubičasti produkt s λmax pri 567 nm. Reakcijski uvjeti su optimirani da se dobije maksimalni intenzitet boje. Apsorbancija raste linearno s porašću koncentracije CFZM; sustavi slijede Beerov zakon u koncentracijskom području 210 za MBTH metodu i 1050 µg mL1 za NEDA metodu. LOD i LOQ te vrijednosti korelacijskog koeficijenta su 0,15, 0,79 i 0,50, 2,61. Uobičajene pomoćne tvari ne smetaju određivanju ceftazidima. Predložene metode su jednostavne, osjetljive, točne i pogodne za primjenu u kontroli kvalitete

The Effect of Different Irrigant Activation Methods on Postoperative Pain After Endodontic Retreatment

Objective: This study was designed to evaluate the effect of different irrigant activation methods on post operative pain after endodontic retreatment. Materials and Methods : Seventy eight patients need non surgical retreatment in mandibular first molar were involved in the study. The retreatment was performed in two visits ,at first visit cases were randomly divided into three groups according to methods of irrigant activation after root canal retreatment with protaper next rotary Ni-TI system. Group A (n=26) Root canals were irrigated using 2.6% sodium hypochlorite (NaOCl) with manual dynamic agitation using master cone Group B (n=26) Root canals were irrigated using 2.6% sodium hypochlorite (NaOCl) using ultrasonic machine (ultra-x) for 60 seconds. Group C (n=26) Root canals were irrigated using 2.6% sodium hypochlorite (NaOCl) with NaviTip (29-gauge 27 mm) with double side tip. At second visit after one week, obturation was performed using modified single cone technique ans access cavity was filled with coronal restoration. After two visits root canal treatment and a specific method of agitation, depending on each group, the patients were given a questionnaire on which the patient would mark the degree of pain in a scale from 0 to 10 at 6, 12, 24, 48 72 hrs and one week post-obturation. Data were statistically analyzed with a significance level of P ≤0.05. Results: At 6,12,24 hrs, there was significant difference between the groups in pain intensity where control group C (Navitip with side vented needle) showed more pain scores than in the intervention groups (Ultra X and manual dynamic agitation). On the other hand, at 48, 72 hours and 7 days post- operative ,there was no statistically significant difference in pain among tested groups. Conclusion: Agitation of the irrigation is reliable safe to clinican and effective as final step irrigation protocol with successful management of postoperative pain in retreatment cases. The intensity of postoperative pain decreased with time regardless of final irrigation protocol used

Constructed wetland for sustainable and low-cost wastewater treatment: review article

There is a growing need for more sustainable wastewater treatment technologies to provide non-conventional water sources. Constructed Wetland systems (CW) are viewed as a low-cost treatment technology with proven treatment efficiency. CWS can treat a variety of contaminants using low energy and natural systems by altering various design parameters. There are two configuration types of constructed wetlands: vertical (VF) and horizontal flow CW (HF). Both configurations have been widely adopted in both large and pilot scale studies with proven records of reasonable wastewater treatment efficiency. The current article reviews the recent development of CW technology and highlights the main achievements and successful applications for wastewater treatment at various locations. The review has indicated that a considerable removal efficiency is attained while using engineered CW systems with variable treatment rates for various pollutants. The treatment efficiency is a function of various parameters including wastewater type, scale dimensions, applied plant and the retention time. The review compared the treatment efficiency for both VF and HF and has revealed that various removal rates of BOD, COD, TSS, TN, TP and NH₄ was attained using both configurations. Yet, the removal efficiency in the case of VF was slightly higher compared with the HF with an average treatment level of 77% and 68% was achieved in both systems, respectively. The review revealed that the CW is an effective and sustainable technology for wastewater treatment with the initial influent level, microbial biofilm, detention time, plant species and configuration among the most dominating parameters that are directly controlling the removal rates

ASSESSMENT EFFECT OF ALOE VERA, AZADIRACHTA INDICA AND MORINGA OLEIFERA AQUEOUS EXTRACTS ON CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS

Objective: This experiment aims to investigate the hepatotherapeutic effect of Aloe vera (AV), Azadirachta indica (N), and Moringa oleifera (MO).Methods: Eighty albino rats have been divided into ten groups. The first group was fed on a basal diet while the second group was administered paraffin (10 ml/kg body weight) through gavage for four days. The third to the tenth groups received (5 ml/kg body weight) CCl4: liquid paraffin (2:1) for three days followed by (10 ml/kg body weight) CCl4: liquid paraffin (2:1) for one day through gavage. Group three kept without any treatment, other groups then received (AV) (60 mg/kg body weight), (MO) (200 mg/kg body weight), (N) (200 mg/kg body weight), bi-extract of (AV+N), bi-extracts of (AV+MO), bi-extract of (MO+N), and tri-extracts of (AV+N+MO) respectively for 36 d. The liver and blood were studied for hepatotoxicity and antioxidant indices.Results: Biochemical and histopathological analysis revealed that CCl4 elevated plasma liver enzymes (aspartate transaminase, alanine aminotransferase, and gamma glutamyl transferase). Carbon tetrachloride also caused an elevation in erythrocyte content of glutathione with a concomitant increase in the plasma malondialdehyde content, along with marked atrophy of hepatocytes. However, these effects were ameliorated by the treatment of rats with the different extracts.Conclusion: Results showed that administration of the aquatic extracts of Aloe vera, Neem, and Moringa (separately/mixedly) played a therapeutic role against CCl4-induced liver damage by improving liver enzyme activities, antioxidant blood parameters, and a liver histopathological picture of intoxicated rats.Keywords: Aloe vera, Azadirachta indica, Moringa oleifera, CCl4 hepatotoxicity, Antioxidant, Rat hepatocyte

Modulation of metabolic and immunoregulatory pathways in the gut transcriptome of Atlantic Salmon (Salmo salar L.) after early nutritional programming during first feeding with plant-based diet

The authors greatly appreciated Dr Dawn Shewring for providing wet lab resources on time. The authors thank Dr Rodanthi Zindrili and Dr David Huyben for helping with sampling and the aquarium husbandry staff of the Institute of Aquaculture, University of Stirling. The authors would like to thank Novogene for the RNA sequencing during the COVID-19 pandemic and their follow-ups about the project.Peer reviewe

Advanced Protocol of Shock Wave Therapy for Diabetic Foot Ulcer

Abstract: Foot ulceration is one of the most common and severe complications of diabetes mellitus causing hospitalization and amputation of lower limb. Delivery of shock wave therapy stimulates the early expression of angiogenesis-related growth factors so it results in new vessel in-growth that improves blood supply, increases cell proliferation and accelerates tissue regeneration and healing. Purpose of this study was to evaluate the effectiveness of shock wave therapy in enhancing diabetic wound healing. Material & methods Forty diabetic patients with stage (II or III) lower limb ulcers were randomly divided into two groups (shock wave group and control group). Shock wave group received 3 sessions of unfocused shock wave (500 pulses/cm 2 at 0.1 mJ/mm 2 ) one session every week beside traditional wound care, the control group received traditional wound care. The methods of assessment were wound surface area and epithelialization rate. Results showed significant decrease in wound surface area and increase in the rate of epithelialization in shock wave group compared to the control group. Conclusions From the finding of the current study we concluded that shock wave with these parameters (500 pulses/cm 2 at 0.1 mJ/mm 2 ) is an effective, safe, relatively inexpensive, simple and available modality in enhancing and accelerating diabetic wound healing