3,940 research outputs found

    Bit-String Models for Parasex

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    We present different bit-string models of haploid asexual populations in which individuals may exchange part of their genome with other individuals (parasex) according to a given probability. We study the advantages of this parasex concerning population sizes, genetic fitness and diversity. We find that the exchange of genomes always improves these features.Comment: 12 pages including 7 figure

    Knock-down of heat-shock protein 90 and isocitrate lyase gene expression reduced root-knot nematode reproduction.

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    Made available in DSpace on 2018-07-19T01:01:42Z (GMT). No. of bitstreams: 1 PHYTO09140237R.pdf: 775087 bytes, checksum: 95edcbc8a1ffecb0dac1b523acf37dd6 (MD5) Previous issue date: 2015-09-14bitstream/item/129546/1/PHYTO-09-14-0237-R.pd

    A Brazilian regional basic diet-induced chronic malnutrition drives liver inflammation with higher ApoA-I activity in C57BL6J mice

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    Malnutrition is still considered endemic in many developing countries. Malnutrition-enteric infections may cause lasting deleterious effects on lipid metabolism, especially in children living in poor settings. The regional basic diet (RBD), produced to mimic the Brazilian northeastern dietary characteristics (rich in carbohydrate and low in protein) has been used in experimental malnutrition models, but few studies have explored the effect of chronic RBD on liver function, a central organ involved in cholesterol metabolism. This study aimed to investigate whether RBD leads to liver inflammatory changes and altered reverse cholesterol metabolism in C57BL6/J mice compared to the control group, receiving a standard chow diet. To evaluate liver inflammation, ionized calcium-binding adapter protein-1 (IBA-1) positive cell counting, interleukin (IL)-1b immunohistochemistry, and tumor necrosis factor (TNF)-a and IL-10 transcription levels were analyzed. In addition, we assessed reverse cholesterol transport by measuring liver apolipoprotein (Apo)E, ApoA-I, and lecithin-cholesterol acyltransferase (LCAT) by RT-PCR. Furthermore, serum alanine aminotransferase (ALT) was measured to assess liver function. RBD markedly impaired body weight gain compared with the control group (Po0.05). Higher hepatic TNF-a (Po0.001) and IL-10 (Po0.01) mRNA levels were found in RBD-challenged mice, although without detectable non-alcoholic fatty liver disease. Marked IBA-1 immunolabeling and increased number of positive-IBA-1 cells (presumably Kupffer cells) were found in the undernourished group. No statistical difference in serum ALT was found. There was also a significant increase in ApoA-I mRNA expression in the undernourished group, but not ApoE and LCAT, compared with the control. Altogether our findings suggested that chronic RBD-induced malnutrition leads to liver inflammation with increased ApoA-I activity

    Thermodynamics and conformal properties of XXZ chains with alternating spins

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    The quantum periodic XXZ chain with alternating spins is studied. The properties of the related R-matrix and Hamiltonians are discussed. A compact expression for the ground state energy is obtained. The corresponding conformal anomaly is found via the finite-size computations and also by means of the Bethe ansatz method. In the presence of an external magnetic field, the magnetic susceptibility is derived. The results are also generalized to the case of a chain containing several different spins.Comment: 28 pages, LaTeX2
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