2,727 research outputs found
Corrections for pumped SBE 41CP CTDs determined from stratified tank experiments
Author Posting. © American Meteorological Society, 2019. This article is posted here by permission of American Meteorological Society for personal use, not for redistribution. The definitive version was published in Journal of Atmospheric and Oceanic Technology 36(4), (2019): 733-744, doi:10.1175/JTECH-D-18-0050.1.Sea-Bird Scientific SBE 41CP CTDs are used on autonomous floats in the global Argo ocean observing program to measure the temperature and salinity of the upper ocean. While profiling, the sensors are subject to dynamic errors as they profile through vertical gradients. Applying dynamic corrections to the temperature and conductivity data reduces these errors and improves sensor accuracy. A series of laboratory experiments conducted in a stratified tank are used to characterize dynamic errors and determine corrections. The corrections are adapted for Argo floats, and recommendations for future implementation are presented.2020-04-2
Reply to "comments on 'corrections for pumped SBE 41CP CTDs determined from stratified tank experiments'"
© The Author(s), 2020. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Martini, K. I., Murphy, D. J., Schmitt, R. W., & Larson, N. G. Reply to "comments on 'corrections for pumped SBE 41CP CTDs determined from stratified tank experiments'". Journal of Atmospheric and Oceanic Technology, 37(2), (2020): 357-363, doi:10.1175/JTECH-D-19-0171.1.The response in Johnson (2020) that the method used to determine cell thermal mass correction coefficients for SBE 41CP CTD data from Argo floats is biased as determined by Martini et al. (2019) is valid. However, the recommendation for correction coefficients should not be followed due to these three errors in Johnson (2020):
Alignment is as large a source of dynamic error as cell thermal mass in the SBE 41CP CTD.
Order of operations was overlooked, so that cell thermal mass is used to correct for alignment errors caused by the temporal mismatch of temperature and conductivity.
The cell thermal mass corrections determined in Johnson et al. (2007) and Johnson (2020) also bias salinity.
In this response we will do the following:
Detail how the corrections in Johnson (2020) are biased because the optimization procedure does not accurately model physics in the tank and conductivity cell.
Verify using in situ data from Argo floats deployed in the ocean that alignment is a significant source of error for the SBE 41CP as shown in Martini et al. (2019).
Determine cell thermal mass correction coefficients from the stratified tank experiment merging the methods of Johnson (2020) and Martini et al. (2019) to optimize against a model that better represents the physics in the tank and conductivity cell.
Compare the corrections using in situ data using the coefficients determined in Johnson et al. (2007), Martini et al. (2019), Johnson (2020), and this manuscript.Thanks to Pelle Robbins for finding the in situ profiles used for this analysis in the vast database of Argo floats, John Gilson showing me how to access that high-resolution data, Ray Schmitt for use of the stratified tank, Susan Wijffels, Breck Owens, and Annie Wong for intellectual support, and Diego Sorrentino and Vlad Simontov for validating the sampling scheme in the SBE 41CP.2020-08-2
Surgical Resection of Recurrent Lung Cancer in Patients Following Curative Resection
We reviewed our experience with resection of recurrent lung cancer to evaluate the benefit and risk of the procedure. From December 1994 to December 2003, 29 consecutive patients underwent pulmonary resections for recurrent lung cancer. The mean duration from the first resection to second surgery was 25.4±15.1 months for the definite 2nd primary lung cancer (n=20) and 8.9±5.7 months for metastatic lung cancer (n=9). The procedures at the second operations were completion-pneumonectomy in 11 patients, lobectomy in 5 patients, wedge resection in 12 patients and resection and anastomosis of trachea in 1 patient. Morbidity was observed in 6 (21%) of the patients and the in-hospital mortality was two patients (7%) after the repeated lung resection. Tumor recurrence after reoperation was observed in 14 patients (48%). The actuarial 5-yr survival rate was 69% and the 5-yr disease free rate following reoperation was 44%. No significant difference was found in overall survival and disease free survival between the 2nd primary lung cancer group and the metastatic lung cancer group. The recurrence rate following reoperation was significantly different between the wedge resection group and lobectomy/completion pneumonectomy group (p=0.008), but the survival rate was not significantly different (p=0.41). Surgical intervention for recurrent lung cancers can be performed with acceptable mortality and morbidity. If tolerable, completion pneumonectomy or lobectomy is recommended for resection of recurrent lung cancer
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Near-Inertial Internal Waves and Sea Ice in the Beaufort Sea
The evolution of the near-inertial internal wavefield from ice-free summertime conditions to ice-covered wintertime conditions is examined using data from a yearlong deployment of six moorings on the Beaufort continental slope from August 2008 to August 2009. When ice is absent, from July to October, energy is efficiently transferred from the atmosphere to the ocean, generating near-inertial internal waves. When ice is present, from November to June, storms also cause near-inertial oscillations in the ice and mixed layer, but kinetic energy is weaker and oscillations are quickly damped. Damping is dependent on ice pack strength and morphology. Decay scales are longer in early winter (NovemberâJanuary) when the new ice pack is weaker and more mobile, decreasing in late winter (FebruaryâJune) when the ice pack is stronger and more rigid. Efficiency is also reduced, as comparisons of atmospheric energy available for internal wave generation to mixed layer kinetic energies indicate that a smaller percentage of atmospheric energy is transferred to near-inertial motions when ice concentrations are >90%. However, large kinetic energies and shears are observed during an event on 16 December and spectral energy is elevated above GarrettâMunk levels, coinciding with the largest energy flux predicted during the deployment. A significant amount of near-inertial energy is episodically transferred to the internal wave band from the atmosphere even when the ocean is ice covered; however, damping by ice and less efficient energy transfer still leads to low Arctic internal wave energy in the near-inertial band. Increased kinetic energy below 300m when ice is forming suggests some events may generate internal waves that radiate into the Arctic Ocean interior.This is the publisherâs final pdf. The published article is copyrighted by the American Meteorological Society and can be found at: http://journals.ametsoc.org/loi/phoc.Keywords: Geographic location/entity, Sea ice, Atmosphere-ocean interaction, Arctic, Circulation/Dynamics, Internal wavesKeywords: Geographic location/entity, Sea ice, Atmosphere-ocean interaction, Arctic, Circulation/Dynamics, Internal wave
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Observations of Internal Tides on the Oregon Continental Slope
A complex superposition of locally forced and shoaling remotely generated semidiurnal internal tides occurs on the Oregon continental slope. Presented here are observations from a zonal line of five profiling moorings deployed across the continental slope from 500 to 3000 m, a 24-h expendable current profiler (XCP) survey, and five 15â48-h lowered ADCP (LADCP)/CTD stations. The 40-day moored deployment spans three spring and two neap tides, during which the proportions of the locally and remotely forced internal tides vary. Baroclinic signals are strong throughout spring and neap tides, with 4â5-day-long bursts of strong crossslope baroclinic semidiurnal velocity (uââ > 0.05 m sâ»Âč) and vertical displacement (ζââ > 100 m). Energy fluxes exhibit complex spatial and temporal patterns throughout both tidal periods. During spring tides, local barotropic forcing is strongest and energy flux over the slope is predominantly offshore (westward). During neap tides, shoaling remotely generated internal tides dominate and energy flux is predominantly onshore (eastward). Shoaling internal tides do not exhibit a strong springâneap cycle and are also observed during the first spring tide, indicating that they originate from multiple sources. The bulk of the remotely generated internal tide is hypothesized to be generated from south of the array (e.g., Mendocino Escarpment), because energy fluxes at the deep mooring 100 km offshore are always directed northward. However, fluxes on the slope suggest that the northbound internal tide is turned onshore, most likely by reflection from large-scale bathymetry. This is verified with a simple three-dimensional model of mode-1 internal tides propagating obliquely onto a near-critical slope, whose output conforms fairly well to observations, in spite of its simplicity
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Internal Bores and Breaking Internal Tides on the Oregon Continental Slope
Observations of breaking internal tides on the Oregon continental slope during a 40-day deployment of 5 moorings along 43°12'N are presented. Remotely generated internal tides shoal onto the slope, steepen, break, and form turbulent bores that propagate upslope independently of the internal tide. A high-resolution snapshot of a single bore is captured from lowered acoustic Doppler current profilers (LADCP)/CTD profiles in a 25-h time series at 1200 m. The bore is cold, salty, over 100 m tall, and has a turbulent head where instantaneous dissipation rates are enhanced (Δ > 10â»â¶ W kgâ»Âč) and sediment is resuspended. At the two deepest slope moorings (1452 and 1780 m), similar borelike phenomena are observed in near-bottom high-resolution temperature time series. Mean dissipation rates and diapycnal diffusivities increase by a factor of 2 when bores are present (Δ[superscript -bores] > 10â»8 W kgâ»Âč and K [superscript over bar (bores)(rho)] > 10â»Âł m sâ»Âč) and observed internal tides are energetic enough to drive these enhanced dissipation rates. Globally, the authors estimate an average of 1.3 kW mâ»Âč of internal tide energy flux is directed onto continental slopes. On the Oregon slope, internal tide fluxes are smaller, suggesting that it is a relatively weak internal tide sink. Mixing associated with the breaking of internal tides is therefore likely to be larger on other continental slopes.This is the publisherâs final pdf. The published article is copyrighted by the American Meteorological Society and can be found at: http://www.ametsoc.org/.Keywords: Hawaiian Ridge, Rough topography, Tidal energy, Central North Pacific, Turbulent dissipation, Deep ocean, Wave reflection, Monterey Submarine Canyon, Gravity waves, Abyssal OceanKeywords: Hawaiian Ridge, Rough topography, Tidal energy, Central North Pacific, Turbulent dissipation, Deep ocean, Wave reflection, Monterey Submarine Canyon, Gravity waves, Abyssal Ocea
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The Cascade of Tidal Energy from Low to High Modes on a Continental Slope
The linear transfer of tidal energy from large to small scales is quantified for small tidal excursion over a near-critical continental slope. A theoretical framework for low-wavenumber energy transfer is derived from âflat bottomâ vertical modes and evaluated with observations from the Oregon continental slope. To better understand the observations, local tidal dynamics are modeled with a superposition of two idealized numerical simulations, one forced by local surface-tide velocities and the other by an obliquely incident internal tide generated at the Mendocino Escarpment 315 km southwest of the study site. The simulations reproduce many aspects of the observed internal tide and verify the modal-energy balances. Observed transfer of tidal energy into high-mode internal tides is quantitatively consistent with observed turbulent kinetic energy (TKE) dissipation. Locally generated and incident simulated internal tides are superposed with varying phase shifts to mimic the effects of the temporally varying mesoscale. Altering the phase of the incident internal tide alters (i) internal-tide energy flux, (ii) internal-tide generation, and (iii) energy conversion to high modes, suggesting that tidally driven TKE dissipation may vary between 0 and 500 watts per meter of coastline on 3â5-day time scales. Comparison of observed in situ internal-tide generation and satellite-derived estimates of surface-tide energy loss is inconclusive.Keywords: Internal waves, Diapycnal mixing, Continental shelf/slope, Tides, Topographic effectsKeywords: Internal waves, Diapycnal mixing, Continental shelf/slope, Tides, Topographic effect
Expression and Differential Responsiveness of Central Nervous System Glial Cell Populations to the Acute Phase Protein Serum Amyloid A
Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves hepatic production of acute-phase proteins, including serum amyloid A (SAA). Extrahepatically, SAA immunoreactivity is found in axonal myelin sheaths of cortex in Alzheimer's disease and multiple sclerosis (MS), although its cellular origin is unclear. We examined the responses of cultured rat cortical astrocytes, microglia and oligodendrocyte precursor cells (OPCs) to master pro-inflammatory cytokine tumour necrosis factor (TNF)-\u3b1 and lipopolysaccaride (LPS). TNF-\u3b1 time-dependently increased Saa1 (but not Saa3) mRNA expression in purified microglia, enriched astrocytes, and OPCs (as did LPS for microglia and astrocytes). Astrocytes depleted of microglia were markedly less responsive to TNF-\u3b1 and LPS, even after re-addition of microglia. Microglia and enriched astrocytes showed complementary Saa1 expression profiles following TNF-\u3b1 or LPS challenge, being higher in microglia with TNF-\u3b1 and higher in astrocytes with LPS. Recombinant human apo-SAA stimulated production of both inflammatory mediators and its own mRNA in microglia and enriched, but not microglia-depleted astrocytes. Co-ultramicronized palmitoylethanolamide/luteolin, an established anti-inflammatory/neuroprotective agent, reduced Saa1 expression in OPCs subjected to TNF-\u3b1 treatment. These last data, together with past findings suggest that co-ultramicronized palmitoylethanolamide/luteolin may be a novel approach in the treatment of inflammatory demyelinating disorders like MS
On the relationships between applied force, photography technique, and the quantification of bruise appearance
Bruising is an injury commonly observed within suspect cases of assault or abuse, yet how a blunt impact initiates bruising and influences its severity is not fully understood. Furthermore, the standard method of documenting a bruise with colour photography is known to have limitations which influence the already subjective analysis of a bruise. This research investigated bruising using a standardised blunt impact, delivered to 18 volunteers. The resulting bruise was imaged using colour, cross polarised (CP) and infrared photography. Timelines of the L*a*b* colour space were determined from both colour and CP images for up to 3 weeks. Overall, no single photographic technique out-performed the others, however CP did provide greater contrast than colour photography. L*a*b* colour space timelines were not attributable any physiological characteristics. Whilst impact force negatively correlated with BMI (R2â=â0.321), neither were associated with any measure of bruise appearance. Due to the inter-subject variability in the bruise response to a controlled infliction, none of the methods in the current study could be used to reliably predict the age of a bruise or the severity of force used in creating a bruise. A more comprehensive approach combining impact characteristics, tissue mechanics, enhanced localised physiological measures and improvements in quantifying bruise appearance is likely to be essential in removing subjectivity from their interpretation
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