4 research outputs found
Resumos em andamento - Engenharia Ambiental e Sanitária
No full textResumos em andamento - Engenharia Ambiental e Sanitári
The effects of high-intensity resistance exercise on the blood lipid profile and liver function in hypercholesterolemic hamsters
No full textIt is well established that atherogenic dyslipidemia, characterized by high levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein (LDL) cholesterol and low levels of high-density lipoprotein (HDL) cholesterol, constitutes important risk factors for cardiovascular disease. Regular exercise has been associated with a reduced risk for metabolic diseases. However, studies supporting the concept that resistance exercise is a modifier of blood lipid parameters are often contradictory. the aim of this study was to investigate the effects of high-intensity resistance exercise on the serum levels of TG, TC, HDL and non-HDL cholesterol, glucose, and the liver function enzymes alanine aminotransferase (ALT, EC 2.6.1.2) and aspartate aminotransferase (AST, EC 2.6.1.1) in golden Syrian hamsters (Mesocricetus auratus (Waterhouse, 1839)) fed a hypercholesterolemic diet. Sedentary groups (S) and exercise groups (E) were fed a standard diet (SS and ES) or a cholesterol-enriched diet (standard plus 1% cholesterol, SC and EC). Resistance exercise was performed by jumps in the water, carrying a load strapped to the chest, representing 10 maximum repetitions (10 RM, 30 s rest, five days per week for five weeks). Mean blood sample comparisons were made by ANOVA + Tukey or ANOVA + Kruskal-Wallis tests (p 0.05). However, the EC group increased the glucose, non-HDL, and TC levels in comparison with the ES group. Moreover, the EC group increased the TG levels versus the SC group (p < 0.05). in addition, the ALT levels were increased only by diet treatment. These findings indicated that high-intensity resistance exercise contributed to dyslipidemia in hamsters fed a hypercholesterolemic diet, whereas liver function enzymes did not differ in regards to the exercise protocol.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)University of São PauloUniv São Paulo, Dept Pathol & Legal Med, Ribeirao Preto Med Sch, BR-14049900 Ribeirao Preto, SP, BrazilFed Univ São Paulo UNIFESP, Dept Prevent Med, São Paulo, BrazilFed Univ Santa Catarina UFSC, Florianopolis, SC, BrazilUniv São Paulo, Dept Clin Toxicol & Food Sci Anal, BR-14049900 Ribeirao Preto, SP, BrazilFed Univ Sao Carlos UFSCAR, Dept Exercise Physiol, Sao Carlos, SP, BrazilFed Univ São Paulo UNIFESP, Dept Prevent Med, São Paulo, BrazilWeb of Scienc
