Characteristics of eyes undergoing epiretinal membrane (ERM) peeling.

*<p>after Bonferroni correction a p value <0.005 was considered statistically significant.</p>†<p>mean ± SD.</p

Optical coherence tomography of two eyes with dissimilar characteristics of the epiretinal membrane (ERM): 1A shows almost complete elevation of the ERM and retinal folds in the temporal segment; 1B shows a diffusely adherent ERM to the retinal surface without elevation and minimal nasal folding.

<p>Optical coherence tomography of two eyes with dissimilar characteristics of the epiretinal membrane (ERM): 1A shows almost complete elevation of the ERM and retinal folds in the temporal segment; 1B shows a diffusely adherent ERM to the retinal surface without elevation and minimal nasal folding.</p

Distribution of the investigated gene polymorphisms in patients and controls.

<p>HLAB27 AAU = HLAB27 associated acute anterior uveitis</p><p>IU = intermediate uveitis</p><p>* compared with HLAB27 negative controls</p><p>^† compared with HLAB27 positive controls</p><p>^‡ compared with HLAB27 negative controls and HLAB27 positive controls combined.</p><p>Distribution of the investigated gene polymorphisms in patients and controls.</p

Baseline ocular and systemic parameters.

<p>HLAB27 AAU = HLAB27 associated acute anterior uveitis</p><p>IU = intermediate uveitis</p><p>SD = standard deviation</p><p>Values are n (%) unless otherwise indicate.</p><p>Baseline ocular and systemic parameters.</p

Demographic Characteristics of Patients and Controls.

<p>AAU = Acute Anterior Uveitis</p><p>SD = Standard Deviation</p><p>Values are n (%) unless otherwise indicated. The mean age for the patient group states the age of onset of the disease.</p

Baseline Ocular and Systemic Parameters.

<p>SD = Standard Deviation</p><p>Values are n (%) unless otherwise indicated.</p

Distribution of the rs703842 A>G Gene Polymorphism in Patients and Controls.

<p>AAU = Acute Anterior Uveitis, OR = Odds Ratio, CI = Confidence Interval, Values are n (%) unless otherwise indicated.</p>*<p>HLA-B27-associated patients vs. HLA-B27-negative control subjects <b><i>p</i></b> = 0.97* (OR = 1.01, 95% CI 0.70–1.46)</p>**<p>HLA-B27-associated patients vs. HLA-B27-positive control subjects <i>p</i> = 0.03** (OR = 0.62, 95% CI 0.41–0.94)</p

Cholesterol efflux capacity.

<p>Apolipoprotein B (apoB)-depleted sera of healthy subjects (control, n = 27) and patients with age-related macular degeneration (AMD, n = 29) were examined for (A) their ability to promote [³H]-cholesterol efflux from macrophages. [³H]-cholesterol-labeled RAW264.7 macrophages were incubated with 2.8% apoB-depleted sera for 4 hours. Cholesterol efflux is expressed as radioactivity in the supernatant relative to total radioactivity (in supernatant and cells). Values shown represent means of two independent experiments.</p

Paraoxonase activity.

<p>Activity of HDL-associated paraoxonase was measured using phenylacetate as substrate. Paraoxonase activity of apoB-depleted sera was calculated from the slopes of the kinetic chart. Values shown represent means of four independent experiments.</p

Anti-oxidative capability.

<p>The anti-oxidative activity of HDL was determined by inhibition of AAPH-initiated oxidation of the fluorescent dye dihydrorhodamine (DHR). Incubation of DHR in presence of apoB-depleted sera from healthy subjects or AMD patients led to a reduction in the oxidation of DHR. Values shown represent means of two independent experiments.</p