Arterial Mg levels in CVVHDF (black squares), CVVH (white squares) at each study time.

<p>Median, IQR in boxes, Min-Max in whiskers.</p

Magnesium inputs (black squares for CVVHDF and white squares for CVVH, both above zero) vs magnesium losses (black triangles for CVVHDF and white triangles for CVVH).

<p>The final balances at each study time (black and white circles) are in the middle. Median, IQR in boxes, Min-Max in whiskers.</p

Flow chart of the 27 hour sequential exposure study.

<p>Ultrafiltration (i.e. net fluid removal) was always administered according to haemodynamic needs (4%TSC trisodium citrate, Qb blood flow, Qd dialysis flow).</p

Configuration of the CRRT circuit under citrate anticoagulation.

<p>Qb, blood flow (L/h); Qc—4% citrate flow (L/h); Qd—dialysis flow (L/h); Qeff,—effluent flow (L/h); UF indicates ultrafiltration, that is, net fluid removal (L/h).</p