Review quality instrument by van Rooyen et al. [23].

<p>Review quality instrument by van Rooyen et al. [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0179031#pone.0179031.ref023" target="_blank">23</a>].</p

Collated concerns and free text responses from survey respondents.

<p>Collated concerns and free text responses from survey respondents.</p

Flowchart of manuscripts included in study.

<p>Flowchart of manuscripts included in study.</p

Characteristics of respondents to the pre-trial questionnaire according to willingness to participate in open peer review.

<p>Numbers (column per cent).</p

Number of open reviews (y-axis) per manuscript (consecutive manuscript number on x-axis).

<p>Number of open reviews (y-axis) per manuscript (consecutive manuscript number on x-axis).</p

Summary of open and regular peer review scores.

<p>Means (SD).</p

RDR corrected hazard ratios^a of incident cancer by cholesterol in quintiles (compared to the lowest quintile) and per unit increment in men.

<p>Abbreviations: CI, confidence interval; HR, hazard ratio; ICD-7, International Classification of Diseases, seventh revision.</p>a<p>HRs estimated from Cox proportional hazard regression models with age as the time scale, stratified by cohort, fasting status, and birth year categories, adjusted for baseline age, body mass index categories, and smoking status. HRs corrected for random error by regression dilution ratio (RDR); conversion into uncorrected HR = exp(ln(HR)*RDR), where RDR = 0.644.</p

Baseline characteristics of study participants in the Metabolic Syndrome and Cancer Project.

<p>Abbreviations: BMI, body mass index; CONOR, Cohort of Norway; MPP, Malmö Preventive Project; NCS, Norwegian Counties Study; Oslo, Oslo study I; SD, standard deviation; VHM&PP, Vorarlberg Heath Monitoring and Prevention Programme; VIP, Västerbotten Intervention Project; 40-y, Age 40-programme.</p

RDR corrected hazard ratios^a of incident cancer by cholesterol in quintiles (compared to the lowest quintile) and per unit increment in women.

<p>Abbreviations: CI, confidence interval; HR, hazard ratio; ICD-7, International Classification of Diseases, seventh revision.</p>a<p>HRs estimated from Cox proportional hazard regression models with age as the time scale, stratified by cohort, fasting status, and birth year categories, adjusted for baseline age, body mass index categories, and smoking status. HRs corrected for random error by regression dilution ratio (RDR); conversion into uncorrected HR = exp(ln(HR)*RDR), where RDR = 0.660.</p

Hazard ratio (HRs) for mortality across the Relative Index of Inequality (RII) in men (blue diamonds) and women (red squares), in Northern (Norway, Sweden, Denmark), Central (UK, Netherlands, and Germany), and Southern (Spain, Italy, and Greece) European countries; fully adjusted model (including smoking status at recruitment, BMI in 2.5 kg/m² categories, alcohol consumption at recruitment, leisure physical activity, and fruit and vegetables consumption, and stratifyied by age and centre of recruitment).

<p>Hazard ratio (HRs) for mortality across the Relative Index of Inequality (RII) in men (blue diamonds) and women (red squares), in Northern (Norway, Sweden, Denmark), Central (UK, Netherlands, and Germany), and Southern (Spain, Italy, and Greece) European countries; fully adjusted model (including smoking status at recruitment, BMI in 2.5 kg/m² categories, alcohol consumption at recruitment, leisure physical activity, and fruit and vegetables consumption, and stratifyied by age and centre of recruitment).</p