Regional Opportunities and Policy Initiatives for New Venture Creation

This paper investigates the determinants of new venture creation across industries and locations for 103 Italian provinces between 1997 and 2003. We allow for differences in regional opportunities across industries and investigate the impact of a range of factors on entrepreneurship in different industries: manufacturing, retailing and wholesaling, hotels and restaurants. Our results show that wage costs deter entry in manufacturing and that regions with industrial districts are characterized by higher start-up rates. Firm entry in commercial sectors appears higher in large cities and areas with strong economic progress. For hotels and restaurants we find that tourism positively influences new firm formation. In terms of policy we do not find a significant effect of recently introduced regional laws promoting new firm formation

Cross-layer Perceptual ARQ for Video Communications over 802.11e Wireless Networks

This work presents an application-level perceptual ARQ algorithm for video streaming over 802.11e wireless networks. A simple and effective formula is proposed to combine the perceptual and temporal importance of each packet into a single priority value, which is then used to drive the packet-selection process at each retransmission opportunity. Compared to the standard 802.11 MAC-layer ARQ scheme, the proposed technique delivers higher perceptual quality because it can retransmit only the most perceptually important packets reducing retransmission bandwidth waste. Video streaming of H.264 test sequences has been simulated with ns in a realistic 802.11e home scenario, in which the various kinds of traffic flows have been assigned to different 802.11e access categories according to the Wi-Fi alliance WMM specification. Extensive simulations show that the proposed method consistently outperforms the standard link-layer 802.11 retransmission scheme, delivering PSNR gains up to 12 dB while achieving low transmission delay and limited impact on concurrent traffic. Moreover, comparisons with a MAC-level ARQ scheme which adapts the retry limit to the type of frame contained in packets and with an application-level deadline-based priority retransmission scheme show that the PSNR gain offered by the proposed algorithm is significant, up to 5 dB. Additional results obtained in a scenario in which the transmission relies on an intermediate node (i.e., the access point) further confirms the consistency of the perceptual ARQ performance. Finally, results obtained by varying network conditions such as congestion and channel noise levels show the consistency of the improvements achieved by the proposed algorithm

The Ehrenfest urn revisited: Playing the game on a realistic fluid model

The Ehrenfest urn process, also known as the dogs and fleas model, is realistically simulated by molecular dynamics of the Lennard-Jones fluid. The key variable is Delta z, i.e. the absolute value of the difference between the number of particles in one half of the simulation box and in the other half. This is a pure-jump stochastic process induced, under coarse graining, by the deterministic time evolution of the atomic coordinates. We discuss the Markov hypothesis by analyzing the statistical properties of the jumps and of the waiting times between jumps. In the limit of a vanishing integration time-step, the distribution of waiting times becomes closer to an exponential and, therefore, the continuous-time jump stochastic process is Markovian. The random variable Delta z behaves as a Markov chain and, in the gas phase, the observed transition probabilities follow the predictions of the Ehrenfest theory.Comment: Accepted by Physical Review E on 4 May 200

Treatment of malignant peripheral nerve sheath tumors in pediatric NF1 disease

Background: Malignant peripheral nerve sheath tumors (MPNSTs) are rare yet highly aggressive soft tissue sarcomas. Children with neurofibromatosis type 1 (NF1) have a 10% lifetime risk for development of MPNST. Prognosis remains poor and survival seems worse for NF1 patients. Methods: This narrative review highlights current practices and pitfalls in the management of MPNST in pediatric NF1 patients. Results: Preoperative diagnostics can be challenging, but PET scans have shown to be useful tools. More recently, functional MRI holds promise as well. Surgery remains the mainstay treatment for these patients, but careful planning is needed to minimize postoperative morbidity. Functional reconstructions can play a role in improving functional status. Radiotherapy can be administered to enhance local control in selected cases, but care should be taken to minimize radiation effects as well as reduce the risk of secondary malignancies. The exact role of chemotherapy has yet to be determined. Reports on the efficacy of chemotherapy vary as some report lower effects in NF1 populations. Promisingly, survival seems to ameliorate in the last few decades and response rates of chemotherapy may increase in NF1 populations when administering it as part of standard of care. However, in metastasized disease, response rates remain poor. New systemic therapies are therefore desperately warranted and multiple trials are currently investigating the role of drugs. Targeted drugs are nevertheless not yet included in first line treatment. Conclusion: Both research and clinical efforts benefit from multidisciplinary approaches with international collaborations in this rare malignancy

Asymptotic Energy Dependence of Hadronic Total Cross Sections from Lattice QCD

The nonperturbative approach to soft high-energy hadron-hadron scattering, based on the analytic continuation of Wilson-loop correlation functions from Euclidean to Minkowskian theory, allows to investigate the asymptotic energy dependence of hadron-hadron total cross sections in lattice QCD. In this paper we will show, using best fits of the lattice data with proper functional forms satisfying unitarity and other physical constraints, how indications emerge in favor of a universal asymptotic high-energy behavior of the kind B log^2 s for hadronic total cross sections.Comment: Revised and extended version; 29 pages, 4 figure

Steady-state spectra, current and stability diagram of a quantum dot: a non-equilibrium Variational Cluster Approach

We calculate steady-state properties of a strongly correlated quantum dot under voltage bias by means of non-equilibrium Cluster Perturbation Theory and the non-equilibrium Variational Cluster Approach, respectively. Results for the steady-state current are benchmarked against data from accurate Matrix Product State based time evolution. We show that for low to medium interaction strength, non-equilibrium Cluster Perturbation Theory already yields good results, while for higher interaction strength the self-consistent feedback of the non-equilibrium Variational Cluster Approach significantly enhances the accuracy. We report the current-voltage characteristics for different interaction strengths. Furthermore we investigate the non-equilibrium local density of states of the quantum dot and illustrate that within the variational approach a linear splitting and broadening of the Kondo resonance is predicted which depends on interaction strength. Calculations with applied gate voltage, away from particle hole symmetry, reveal that the maximum current is reached at the crossover from the Kondo regime to the doubly-occupied or empty quantum dot. Obtained stability diagrams compare very well to recent experimental data [Phys. Rev. B, 84, 245316 (2011)].Comment: 13 pages, 7 figure

Prognostic Significance of Immunohistochemical Markers and Genetic Alterations in Malignant Peripheral Nerve Sheath Tumors: A Systematic Review

Background: Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive soft tissue sarcomas with dis