Flowchart of patients who provided useful samples.

<p>Flowchart of patients who provided useful samples.</p

Data for goal disturbance, cortisol levels, CAR, DCS, and COMT over time (n = 72).

<p>Paired samples t-tests were used to test significant differences between time 2 and time 3, and ANOVA’s with COMT genotype as between-group factor to test significant differences in cortisol levels between genotypes.</p

Hierarchical regression analyses predicting cortisol 7 months post-diagnosis (Time 2).

<p>*<i>p</i> < 0.05</p><p>**<i>p</i> < 0.01</p><p>Hierarchical regression analyses predicting cortisol 7 months post-diagnosis (Time 2).</p

Hierarchical regression analyses predicting cortisol 18 months post-diagnosis (Time 3).

<p>*<i>p</i> < 0.05</p><p>**<i>p</i> < 0.01</p><p>Hierarchical regression analyses predicting cortisol 18 months post-diagnosis (Time 3).</p

Patients’ demographics.

<p>(n = 72) (percentages may not add up to 100% due to missing data).</p><p>Patients’ demographics.</p

Alpha-amylase patterns over 30 days stratified by beep-time (morning, afternoon and evening values).

<p>Graphs of pair-matched individuals are placed alongside each other (e.g. D1 and N1). In the corner of the graphs the following information is displayed: identification number (D = depressed, N = non-depressed), gender (F = female, M = male), age in years, BMI, evening beep-time, and, if smoking ‘Sm’. Descriptive statistics at the opposite side of the graphs display m, the mean of the series and s2, the variance of the series.</p

Characteristics of depressed and non-depressed groups.

<p>Characteristics of depressed and non-depressed groups.</p

Results of multilevel analysis of relationship between depression status and cortisol and α-amylase measures.

<p>Note: CI = confidence interval.</p><p>* p<0.05</p><p>**p<0.01</p><p>^†p<0.10</p><p>Results of multilevel analysis of relationship between depression status and cortisol and α-amylase measures.</p

Cortisol patterns over 30 days stratified by beep-time (morning, afternoon and evening values).

<p>Graphs of pair-matched individuals are placed alongside each other (e.g. D1 and N1). In the corner of the graphs the following information is displayed: identification number (D = depressed, N = non-depressed), gender (F = female, M = male), age in years, BMI, evening beep-time, and, if smoking ‘Sm’. Descriptive statistics at the opposite side of the graphs display m, the mean of the series and s², the variance of the series.</p