788 research outputs found

    Structured Optical Materials Controlled by Light

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    Materials of which the optical response is determined by their structure are of much interest both for their fundamental properties and applications. Examples range from simple gratings to photonic crystals. Obtaining control over the optical properties is of crucial importance in this context, and it is often attempted by electro-optical effect or by using magnetic fields. In this paper, we introduce the use of light to switch and tune the optical response of a structured material, exploiting a physical deformation induced by light itself. In this new strategy, light drives an elastic reshaping, which leads to different spectral properties and hence to a change in the optical response. This is made possible by the use of liquid crystalline networks structured by Direct Laser Writing. As a proof of concept, a grating structure with sub-millisecond time-response is demonstrated for optical beam steering exploiting an optically induced reversible shape-change. Experimental observations are combined with finite-element modeling to understand the actuation process dynamics and to obtain information on how to tune the time and the power response of this technology. This optical beam steerer serves as an example for achieving full optical control of light in broad range of structured optical materials

    Duplex DNA from Sites of Helicase-Polymerase Uncoupling Links Non-B DNA Structure Formation to Replicative Stress

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    BACKGROUND: Replication impediments can produce helicase-polymerase uncoupling allowing lagging strand synthesis to continue for as much as 6 kb from the site of the impediment. MATERIALS AND METHODS: We developed a cloning procedure designed to recover fragments from lagging strand near the helicase halt site. RESULTS: A total of 62% of clones from a p53-deficient tumor cell line (PC3) and 33% of the clones from a primary cell line (HPS-19I) were within 5 kb of a G-quadruplex forming sequence. Analyses of a RACK7 gene sequence, that was cloned multiple times from the PC3 line, revealed multiple deletions in region about 1 kb from the cloned region that was present in a non-B conformation. Sequences from the region formed G-quadruplex and i-motif structures under physiological conditions. CONCLUSION: Defects in components of non-B structure suppression systems (e.g. p53 helicase targeting) promote replication-linked damage selectively targeted to sequences prone to G-quadruplex and i-motif formation

    The impact of bilingualism on executive functions in children and adolescents: a systematic review based on the PRISMA method

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    Approximately half of the world's population is bilingual or multilingual. The bilingual advantage theory claims that the constant need to control both known languages, that are always active in the brain, to use the one suitable for each specific context improves cognitive functions and specifically executive functions. However, some authors do not agree on the bilingual effect, given the controversial results of studies on this topic. This systematic review aims to summarize the results of studies on the relationship between bilingualism and executive functions. The review was conducted according to PRISMA-statement through searches in the scientific database PsychINFO, PsycARTICLES, MEDLINE, and PUBMED. Studies included in this review had at least one bilingual and monolingual group, participants aged between 5 and 17 years, and at least one executive function measure. Studies on second language learners, multilingual people, and the clinical population were excluded. Fifty-three studies were included in the systematic review. Evidence supporting the bilingual effect seems to appear when assessing inhibition and cognitive flexibility, but to disappear when working memory is considered. The inconsistent results of the studies do not allow drawing definite conclusions on the bilingual effect. Further studies are needed; they should consider the role of some modulators (e.g., language history and context, methodological differences) on the observed results

    Two-Fiber Self-Homodyne Transmission for Short-Reach Coherent Optical Communications

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    We experimentally evaluate the performance of two-fiber self-homodyne short-reach transmission, showing that it enables the use of DFB laser provided that the optical path mismatch is kept below 1 m for PM-QPSK and 0.5 m for PM-16QAM

    Photonic Microhand with Autonomous Action

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    Grabbing and holding objects at the microscale is a complex function, even for microscopic living animals. Inspired by the hominid-type hand, a microscopic equivalent able to catch microelements is engineered. This microhand is light sensitive and can be either remotely controlled by optical illumination or can act autonomously and grab small particles on the basis of their optical properties. Since the energy is delivered optically, without the need for wires or batteries, the artificial hand can be shrunk down to the micrometer scale. Soft material is used, in particular, a custom-made liquid-crystal network that is patterned by a photolithographic technique. The elastic reshaping properties of this material allow finger movement, using environmental light as the only energy source. The hand can be either controlled externally (via the light field), or else the conditions in which it autonomously grabs a particle in its vicinity can be created. This microrobot has the unique feature that it can distinguish between particles of different colors and gray levels. The realization of this autonomous hand constitutes a crucial element in the development of microscopic creatures that can perform tasks without human intervention and self-organized automation at the micrometer scale

    Phase Noise Impact and scalability of self-homodyne short-reach coherent transmission using DFB lasers

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    We investigate on a two-fiber short-reach self-homodyne coherent transmission system without optical amplification, where the same transmission laser is used to generate a modulated signal carrying useful data and a continuous wave signal, which serves as a local oscillator at the receiver side. Target of the work is to determine by experiments and theoretical models under which conditions DFB lasers can be used instead of more expensive ECL lasers. After careful characterization of lasers phase noise in terms of linewidth as a function of the mismatch between the optical paths of the signal and of the local oscillator, the performance of two laser technologies is investigated in the proposed transmission setup, showing that commercial DFB laser can be used, provided that the optical path mismatch between the two fibers is kept below 1.8 meter for 28 GBaud PM-QPSK and 0.8 meter for PM-16QAM modulation format in combination with a soft-decision forward error correction algorithm. After an experimental demonstration, we theoretically investigate the scalability laws of the proposed systems in different configuration flavours

    An improved fault mitigation strategy for CUDA Fermi GPUs

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    High computation is a predominant requirement in many applications. In this field, Graphic Processing Units (GPUs) are more and more adopted. Low prices and high parallelism let GPUs be attractive, even in safety critical applications. Nonetheless, new methodologies must be studied and developed to increase the dependability of GPUs. This paper presents an improved fault mitigation strategy against permanent faults for CUDA Fermi GPUs. The proposed approach exploits the reverse engineering of the block scheduling policy in CUDA Fermi GPUs in order to minimize the fault mitigation timing overhead. The graceful performance degradation achieved by the proposed technique outperforms multithreaded CPU implementations and other fault mitigation strategies for CUDA GPU, even in presence of multiple permanent faults

    Multichannel remote polarization control enabled by nanostructured Liquid Crystalline Networks

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    In this article we demonstrate that a grating fabricated through nanoscale volumetric crosslinking of a liquid crystalline polymer enables remote polarization control over the diffracted channels. This functionality is a consequence of the responsivity of liquid crystal networks upon light stimuli. Tuning the photonic response of the device is obtained thanks to both a refractive index and a shape change of the grating elements induced by a molecular rearrangement under irradiation. In particular, the material anisotropy allows for nontrivial polarization state management over multiple beams. Absence of any liquid component and a time response down to 0.2 milliseconds make our device appealing in the fields of polarimetry and optical communications.Comment: 16 pages,8 figures, featured article in AL

    Light‐Powered Microrobots: Challenges and Opportunities for Hard and Soft Responsive Microswimmers

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    Worldwide research in microrobotics has exploded in the past two decades, leading to the development of microrobots propelled in various manners. Despite significant advances in the field and successful demonstration of a wide range of applications, microrobots have yet to become the preferred choice outside a laboratory environment. After introducing available microrobotic propulsion and control mechanisms, microrobots that are manufactured and powered by light are focused herein. Referring to pioneering works and recent interesting examples, light is presented not only as a fabrication tool, by means of twophoton polymerization direct laser writing, but also as an actuator for microrobots in both hard and soft stimuli–responsive polymers. In this scenario, a number of challenges that yet prevent polymeric light-powered microrobots from reaching their full potential are identified, whereas potential solutions to overcome said challenges are suggested. As an outlook, a number of real-world applications that light-powered microrobots should be particularly suited for are mentioned, together with the advances needed for them to achieve such purposes. An interdisciplinary approach combining materials science, microfabrication, photonics, and data science should be conducive to the next generation of microrobots and will ultimately foster the translation of microrobotic applications into the real world

    Outdoor characterization of dye solar cells: first results

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    The Centre for Hybrid and Organic Solar Energy (CHOSE) at the University of Rome Tor Vergata is focusing its efforts in developing reliable and stable dye solar cells and modules. The CHOSE development program foresees that new cells and modules will be tested both indoor and outdoor in order to have an overview of the real performances of the devices. This is generally a key point for a correct evaluation of the actual performances of any photovoltaic technology. In October 2008 an outdoor measurement campaign on Dye Solar Cells has been started. Two different types of cells have been built in the laboratory, varying the characteristics of the TiO2 film, in order to evaluate their behaviour in real outdoor environment. Data collected during the two first month of outdoor cell exposure are presented in this paper. Daily trends of cell efficiency as a function of the environmental parameters and of the cell temperature have been investigated, focusing on the cell behaviour at low irradiance levels
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