Reliability and Initial Validation of the Ulcerative Colitis Endoscopic Index of Severity

Background & AimsWe studied the reliability of the previously described Ulcerative Colitis Endoscopic Index of Severity (UCEIS) and validated it with an independent cohort of investigators.MethodsWe created a new library of 57 videos of flexible sigmoidoscopy and stratified them based on disease severity. Twenty-five investigators were each randomly assigned to assess 28 videos (which included 4 duplicates to assess intraobserver reliability). Investigators were blinded to clinical details except for 2 of 4 duplicated videos (to assess the impact of knowledge of symptoms on assessment). Three descriptors (“vascular pattern”, “bleeding”, and “erosions and ulcers”) comprising the UCEIS were scored with a visual analogue scale (VAS) to assess overall severity. Intrainvestigator and interinvestigator agreement was characterized by κ statistical analysis; reliability ratios were used to compare VAS and UCEIS scores.ResultsThere was a high level of correlation between UCEIS scores and overall assessment of severity (correlation coefficient, 0.93). Internal consistency (Cronbach α analysis) was 0.86. Intrainvestigator and interinvestigator reliability ratios for UCEIS scores were 0.96 and 0.88, respectively. Intrainvestigator agreement in determination of the UCEIS score was good (κ = 0.72), with individual descriptors ranging from a κ of 0.47 (for bleeding) to 0.87 (for vascular pattern). Interinvestigator agreement in determination of UCEIS scores was moderate (κ = 0.50), with descriptors ranging from a κ of 0.48 (for bleeding) to 0.54 (for vascular pattern). Intrainvestigator variability in determining UCEIS scores did not change appreciably when a video was presented with clinical details.ConclusionsThe UCEIS and its components show satisfactory intrainvestigator and interinvestigator reliability. Among investigators, the UCEIS accounted for a median of 86% of the variability in evaluation of overall severity on the VAS when assessing the endoscopic severity of UC and was unaffected by knowledge of clinical details

Immediate Duodenal Delivery Versus Delayed Oral Ingestion of Capsule Endoscopy : Is the Sooner the Better? a Prospective Comparison of Small Bowel Visualization Quality, According to a Computed Assessment of Cleansing Score

International audienc

Comparaison, à l’aide d’un indice colorimétrique automatisé, de lapréparation intestinale selon deux modalités de vidéocapsule (VCE) dugrêle : largage duodénal versus ingestion orale différée

National audienceLa VCE du grêle est l’examen de première intention dans les saignements digestifsinexpliqués (SDI). La précocité de réalisation de la VCE est un facteur prédictifindépendant majeur de positivité de la VCE dans les SDI. Le largage duodénal de laVCE au décours immédiat d’une coloscopie normale peut de ce point de vue permettreun gain de temps significatif. La qualité de la préparation selon cette procédure mérited’être comparée à la procédure standard (ingestion de la VCE après purge orale, àdistance du diagnostic de SDI). L’objectif principal était de comparer la qualité depréparation de l'intestin grêle pour VCE après largage duodénal au décours immédiatd'une coloscopie à celle après ingestion orale différée, grâce à un indice colorimétriquede qualité de préparation intestinale (ICQPI)

Development and Validation of a Highly Sensitive and Highly Specific Computed Assessment of Cleansing Score for Small Bowel Capsule Endoscopy

International audienc

Development and Validation of a Computed Assessment of Cleansing Score For Evaluation of the Quality of Small-bowel Visualization in Capsule Endoscopy

International audienc