1 research outputs found
Synthesis and Evaluation of Biotinylated Bivalent HistoBlood Group Antigens for Capturing Human Noroviruses
A panel
of biotinylated bivalent H-type glycans that have been
reported as binding ligands for human noroviruses were synthesized
using a modular synthetic strategy. These glycoconjugates were attached
to streptavidin-coated magnetic beads and used to recover human norovirus
from fecal samples using a magnetic bead-based assay. The biotinylated
bivalent glycans synthesized for this study exhibited similar or better
capturing ability when compared to commercial biotinylated glycopolymers