Odds ratios for CHD in men and women, EPIC-Norfolk 1993–2009 by quartile of plasma PFA concentration, age and sex adjusted, and multivariate adjusted and as a continuous variable, per approximate SD increase.

<p><i>p</i>-Values derived from Wald statistic.</p>a<p>BMI, smoking, alcohol intake, physical activity, plasma vitamin C, social class, education, diabetes, systolic blood pressure.</p>b<p>BMI, smoking, alcohol intake, physical activity, plasma vitamin C, social class, education, diabetes, systolic blood pressure, and cholesterol.</p>c<p>PFAs grouped in categories.</p

Mean plasma concentrations of individual PFAs in men and women, EPIC-Norfolk and age- and sex-adjusted odds ratios for CHD.

a<p>Adjusted for age, sex, and all individual PFAs in the same model for individual PFAs, families of PFA for the families, all as continuous variables.</p>b<p>Adjusted for age, sex, other PFA, BMI, smoking, physical activity, alcohol intake, social class, education, blood pressure.</p

Baseline characteristics of men and women with incident CHD and controls EPIC-Norfolk 1993–2009.

<p>Baseline characteristics of men and women with incident CHD and controls EPIC-Norfolk 1993–2009.</p

Association between baseline serum α-tocopherol and γ-tocopherol and risk of prostate cancer, stratified by disease stage and grade, PLCO Study.

a<p>Odds ratios are based on unconditional logistic regression, adjusted for study center, serum cholesterol, serum β-carotene, age, time since initial screening, and year of blood draw.</p>b<p>Aggressive cases were defined as stage III or IV, or Gleason score ≥ 7.</p

Association between baseline serum α-tocopherol and γ-tocopherol and risk of prostate cancer, stratified by smoking status, PLCO Study.

a<p>Multiplicative interaction tested using the log-likelihood ratio, comparing models with and without an interaction term of tocopherol quintiles crossed with a categorical smoking status variable.</p>b<p>Numbers are cases/controls.</p>c<p>Values are odds ratios (95% confidence intervals), based on unconditional logistic regression and adjusted for study center, serum cholesterol, serum β-carotene, age, time since initial screening, and year of blood draw.</p

Association between baseline serum α-tocopherol, γ-tocopherol, and the α-tocopherol:γ-tocopherol molar ratio and risk of prostate cancer, PLCO Study.

a<p>Odds ratios based on conditional logistic regression (conditioned on age, time since initial screening, and year of blood draw) and adjusted for study center, serum cholesterol and serum β-carotene.</p

Correlations between baseline characteristics and α-tocopherol and γ-tocopherol among controls, PLCO Study.

<p>Correlations between baseline characteristics and α-tocopherol and γ-tocopherol among controls, PLCO Study.</p

Relation between Plasma <i>R249S-</i>mutated <i>DNA</i> and HBs-antigen (HBsAg) and HCV-antibody (HCV-ab).

<p><i>X₂</i> test when compared to cholangiocarcinoma, chronic liver disease and reference group all together (*: p value <0.05; ***: p value <0.001; NA: Not Available; ns: non significant).</p

Box and whisker distributions of <i>TP53 R249S</i>-<i>mutated DNA plasma concentrations</i> (≥150 copies/mL) for the different groups.

<p>Boxes extend from 25^th to 75^th percentiles and are divided by a solid line representing the median of each centre. The median levels for the different groups are: 328 in HCC/no cirrhosis, 273 in HCC/cirrhosis, 252 in CC, 256 in CLD and 202 in R.</p

Geographic distribution of liver cancer cases.

<p>Dots represent the distribution by province. Pie charts describe the distribution of HCC/no cirrhosis (lines), HCC/cirrhosis (full black) and CC (small dots) among the Northwest, Northeast and Central-south parts of the country.</p