Rola pielęgniarki w wykonywaniu alergicznych testów skórnych punktowych u dzieci i dorosłych = The role of the nurse in performing skin allergy testing in children and adults

Czerwińska Pawluk Iwona, Markut–Miotła Ewa. Rola pielęgniarki w wykonywaniu alergicznych testów skórnych punktowych u dzieci i dorosłych = The role of the nurse in performing skin allergy testing in children and adults. Journal of Education, Health and Sport. 2015;5(1):293-304. ISSN 2391-8306. DOI: http://dx.doi.org/10.5281/zenodo.44484http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%281%29%3A293-304https://pbn.nauka.gov.pl/works/689296Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive Deklaracja.Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie.Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r.The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014).© The Author (s) 2015;This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, PolandOpen Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited.This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercialuse, distribution and reproduction in any medium, provided the work is properly cited.The authors declare that there is no conflict of interests regarding the publication of this paper.Received: 02.01.2015. Revised 18.01.2015. Accepted: 21.01.2015. ROLA PIELĘGNIARKI W WYKONYWANIU ALERGICZNYCH TESTÓW SKÓRNYCH PUNKTOWYCH U DZIECI I DOROSŁYCH The role of the nurse in performing skin allergy testing in children and adults Iwona Czerwińska Pawluk Uniwersytecki Szpital Dziecięcy, Lublin ul. Prof. A. Gębali 6Radomska Szkoła Wyższa - Wydział Nauk o Zdrowiu, Radom  Ewa Markut–Miotła Katedra i Zakład Pielęgniarstwa Pediatrycznego Uniwersytetu Medycznego w Lublinie StreszczenieChoroby alergiczne stanowią poważny problem współczesnej medycyny. Złożony i wieloczynnikowy ich patomechanizm jest przyczyną wielu problemów zarówno natury medycznej jak i psychospołecznych.  Rozpoznanie choroby alergicznej jest podstawą wdrożenia metod terapeutycznych minimalizujących objawy choroby. W diagnostyce chorób alergicznych oprócz lekarza ważne miejsce zajmuje pielęgniarka. W ramach diagnostyki alergologicznej istotne jest przeprowadzenie wywiadu z pacjentem i/ lub jego opiekunami, badanie fizykalne, wykonanie testów alergicznych. Testy alergiczne pozwalają na identyfikację alergenu/ alergenów wyzwalających i /lub nasilających objawy chorobowe. Słowa kluczowe: choroby alergiczne, testy alergiczne. The role of the nurse in performing skin allergy testing in children and adults AbstractAllergic diseases are a serious problem of modern medicine. Complex and multifactorial patomechanism is the cause of many medical and psychosocial problems. Diagnosis of an allergic disease is the basis for implementing therapeutic methods that minimize the symptoms of the disease. In addition to the doctor’s role in the diagnostic process an important place occupies the nurse. It is important to carry out physical examination, including taking medical history of the patient and performing skin allergy testing. Skin tests enable the identification of alergen(s) triggering and/or intensifying allergic symptoms. Key words: allergic diseases, skin allergy tests

An innovative approach for better understanding of milk allergy

Introduction: Cow’s milk and its products are popular components of the diet all over the world. Proteins contained in it, such as casein (Bos d 8), α-lactalbumin (Bos d 4), β-lactoglobulin (Bos d 5) and bovine serum albumin (Bos d 6, BSA), can cause troublesome symptoms. Among the proteins mentioned, casein is the most frequent cause of all milk allergies. It is worth mentioning that it is a protein that does not change its properties after thermal and enzymatic treatment. Therefore, casein allergic patients must avoid dairy products in even trace amounts. Aim of the study: The aim of the study is to present the benefits of molecular diagnostics of allergy in cow’s milk allergy. Description of the state of knowledge: In order to diagnose milk allergy, a medical examination should take place with a clinician who will determine the further steps of diagnosis based on the medical interview. For a complete allergy analysis, molecular diagnostics tests can be used to determine which protein the patient is sensitised to. Such an individual patient’s allergy profile is helpful in developing an appropriate diet. Summary: Molecular diagnosis in cow's milk allergy allows to estimate the risk of severe reactions after contact with a specific allergen. On its basis, it is also possible to predict the result of a cow's milk allergen provocation test. By using molecular diagnosis of allergy, it is possible to manage better and control cow's milk allergy in patients. &nbsp

A new insight into diagnosis and management of hen egg allergy

Introduction: A chicken egg is a popular dietary component all over the world. An allergy to this nourishment is more often related to egg white than to yolk, and its first symptoms often appear even before the first year of life. Aim of the study: The aim of the study is to present the benefits of molecular diagnostics of allergy in chicken egg allergy.Description of the state of knowledge: To diagnose an allergy to egg proteins, skin prick tests or the determination of antigen-specific immunoglobulins E are used. However, the most verifying test of a reaction to food is a double-blind challenge.The most allergenic proteins in a chicken egg are ovomucoid (Gal d 1), ovalbumin (Gal d 2), ovotransferrin (Gal d 3), A-livetin (Gal d 5) and lysozyme (Gal d 4). Among the aforementioned proteins, ovomucoid and ovalbumin are the main allergens and the most common causes of egg allergy. It is worth noting that thermal treatment reduces the allergenic potential of ovalbumin, as opposed to ovomucoid. This means that in patients allergic to ovalbumin, a raw egg may cause an allergic reaction, while an egg, e.g. baked egg, should not cause symptoms of hypersensitivity.Summary:​​ Based on molecular diagnostics, it is possible to identify allergenic molecules of a chicken egg, such as ovomucoid, ovalbumin or ovotransferrin. This allows for better control of symptoms of hypersensitivity in patients with egg allergy. Egg yolk is a good source of amino acids and fats. Therefore, thanks to molecular diagnostics of allergy, it is possible to verify the validity of an elimination diet or to create a diet based on heat-treated eggs

Effect of immunostimulation with bacterial lysate on the clinical course of allergic rhinitis and the level of γδT, iNKT and cytotoxic T cells in children sensitized to grass pollen allergens: A randomized controlled trial

BackgroundThere are many drugs for allergic rhinitis (AR), however, these drugs show variable clinical effectiveness and some side effects. Therefore, new methods of AR pharmacotherapy are being sought.ObjectivesThe objectives of this study were to evaluate the efficacy of polyvalent mechanical bacterial lysate (PMBL) therapy in improving the clinical course of grass pollen-induced AR (seasonal AR, SAR) in children and its effect on changes in the blood level of the γδT, iNKT and cytotoxic T cell subsets.MethodsFifty children with SAR were enrolled in this study and were randomly assigned to either the PMBL group or the placebo group. The severity of SAR symptoms was assessed using the total nasal symptom score (TNSS) and visual analogue scale (VAS). During two visits (V1, V2), peak nasal inspiratory flow (PNIF) was measured and peripheral blood was collected for immunological analyses. The study also included 2 telephone contacts (TC1, TC2).ResultsThe severity of the nasal symptoms of SAR on the TNSS scale was revealed to have a significantly lower impact in the PMBL group vs the placebo group at measuring points TC1 and V2 (p = 0.01, p = 0.009, respectively). A statistically significantly lower mean severity of nasal symptoms of SAR on the VAS scale was recorded for children in the PMBL group compared to the placebo group at measuring points TC1, V2 and TC2 (p = 0.04, p = 0.04, p = 0.03, respectively). The compared groups do not show significant differences in terms of PNIF values at individual measuring points. There were no statistically significant changes in immune variables. For both groups, there was a statistically significant association between the level of Th1-like γδT cells and the severity of SAR symptoms expressed on the TNSS scale (p = 0.03) – the lower the level of Th1-like γδT cells, the higher the TNSS value.ConclusionAdministration of sublingual PMBL tablets during the grass pollen season proves to have a high efficacy in alleviating SAR symptoms in children sensitized to grass pollen allergens. Th1-like γδT cells may be used as potential markers for SAR severity in children.Clinical trial registrationClinicalTrials.gov, identifier (NCT04802616)

Rola przepływu wdechowego w optymalnej technice inhalacji z DPI i metody jego pomiaru = Role inspiratory flow at optimal inhalation with a DPI technology and its methods of measurement

Czerwińska Pawluk Iwona, Markut–Miotła Ewa. Rola przepływu wdechowego w optymalnej technice inhalacji z DPI i metody jego pomiaru = Role inspiratory flow at optimal inhalation with a DPI technology and its methods of measurement. Journal of Education, Health and Sport. 2015;5(1):284-292. ISSN 2391-8306. DOI: http://dx.doi.org/10.5281/zenodo.44483 http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%281%29%3A284-292 https://pbn.nauka.gov.pl/works/689292 Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive   Deklaracja. Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie. Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r. The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014). © The Author (s) 2015; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 02.01.2015. Revised 18.01.2015. Accepted: 21.01.2015.   ROLA PRZEPŁYWU WDECHOWEGO W OPTYMALNEJ TECHNICE INHALACJI Z DPI I METODY JEGO POMIARU ROLE INSPIRATORY FLOW AT OPTIMAL INHALATION WITH A DPI TECHNOLOGY AND ITS METHODS OF MEASUREMENT     Iwona Czerwińska Pawluk   Radomska Szkoła Wyższa w Radomiu , Wydział Nauk o Zdrowiu Uniwersytecki Szpital Dziecięcy, Lublin ul. Prof. A. Gębali 6   Ewa Markut–Miotła   Katedra i Zakład Pielęgniarstwa Pediatrycznego Uniwersytetu Medycznego w Lublinie         Streszczenie   Ważne miejsce w terapii schorzeń układu oddechowego zajmują inhalatory  suchego proszku (DPIs). Na wielkość depozycji płucnej leków podawanych z DPIs wpływają czynniki zewnętrzne oraz czynniki zależne od pacjenta. Pośród czynników zależnych od pacjenta szczególne znaczenie ma technika inhalacji, w tym wielkość i jakość wysiłku wdechowego, rodzaj patologii i stan czynnościowy układu oddechowego.  Jednym z parametrów  opisujących wdech chorego jest szczytowy przepływ wdechowy – PIF.  Wielkość PIF jaką pacjent jest w stanie wygenerować zależy od: wieku pacjenta, stanu fizycznego dróg oddechowych i mięśni wdechowych oraz stanu  czynnościowego układu oddechowego. Na wartość PIF wpływa też świadome działanie pacjenta. Wielkość PIF konieczna do aerolizacji i zainhalowania właściwej dawki leku o optymalnym składzie cząstek jest różna dla poszczególnych DPIs. Głównym czynnikiem determinującym to zjawisko jest opór wewnętrzny danego DPI, co z kolei decyduje o ciśnieniu powietrza przechodzącego przez urządzenie i o jego przepływie.  Przepływ wdechowy i inne parametry opisujące wysiłek wdechowy ocenia się przy pomocy metod: ilościowych, półilościowych i jakościowych (orientacyjnych).   Słowa kluczowe: inhalatory suchego proszku (DPIs), szczytowy przepływ wdechowy (PIF).   Abstract   Dry powder inhalers (DPIs) play an important role in the therapy of respiratory track  diseases. Lung deposition via DPI can affect external  and patient -related factors. Particularly important among patient-related elements is an inhalation technique, including quantity and quality of respiratory effort, type of pathology and lung function parameters . One of the parameters describing inspiration maneuver of a patient is peak inspiratory flow-PIF. PIF value generated by an individual depends on: age, inspiratory muscles condition, lung physical and function parameters. Patient’s conscious action also influence on PIF value. PIF necessary for aerolisation and inhaled drug delivery (proper dose of optimal particle) differ between DPIs devices. Main factor determining this proces is internal resistence of each DPI device , which indicates air pressure  and airflow through DPI device. Inspiration flow and other parameters describing inspiration effort can be measured by quantitive, semi-quentitive and qualitive methods.   Key words: dry powder inhalers (DPIs), peak inspiratory flow (PIF)

The Influence of Polyphenols on Atherosclerosis Development

Polyphenols have attracted tremendous attention due to their pro-health properties, including their antioxidant, anti-inflammatory, antibacterial and neuroprotective activities. Atherosclerosis is a vascular disorder underlying several CVDs. One of the main risk factors causing atherosclerosis is the type and quality of food consumed. Therefore, polyphenols represent promising agents in the prevention and treatment of atherosclerosis, as demonstrated by in vitro, animal, preclinical and clinical studies. However, most polyphenols cannot be absorbed directly by the small intestine. Gut microbiota play a crucial role in converting dietary polyphenols into absorbable bioactive substances. An increasing understanding of the field has confirmed that specific GM taxa strains mediate the gut microbiota–atherosclerosis axis. The present study explores the anti-atherosclerotic properties and associated underlying mechanisms of polyphenols. Moreover, it provides a basis for better understanding the relationship between dietary polyphenols, gut microbiota, and cardiovascular benefits

The Efficacy of Black Chokeberry Fruits against Cardiovascular Diseases

Epidemiological studies have emphasized the association between a diet rich in fruits and vegetables and a lower frequency of occurrence of inflammatory-related disorders. Black chokeberry (Aronia melanocarpa L.) is a valuable source of biologically active compounds that have been widely investigated for their role in health promotion and cardiovascular disease prevention. Many in vitro and in vivo studies have demonstrated that consumption of these fruits is associated with significant improvements in hypertension, LDL oxidation, lipid peroxidation, total plasma antioxidant capacity and dyslipidemia. The mechanisms for these beneficial effects include upregulation of endothelial nitric oxide synthase, decreased oxidative stress, and inhibition of inflammatory gene expression. Collected findings support the recommendation of such berries as an essential fruit group in a heart-healthy diet. The aim of this review was to summarize the reports on the impact of black chokeberry fruits and extracts against several cardiovascular diseases, e.g., hyperlipidemia, hypercholesterolemia, hypertension, as well as to provide an analysis of the antioxidant and anti-inflammatory effect of these fruits in the abovementioned disorders