Pathological pregnancy and psychological symptoms in women [Patološka trudnoća i psihički simptomi u žena]

Pregnancy is followed by many physiologic, organic and psychological changes and disorders, which can become more serious in pregnancy followed by complications, especially in women with pathological conditions during pregnancy. The purpose of this study was to find out and analyze the prevalence and intensity of psychological disorders in women with pathological conditions during pregnancy and compare it with conditions in pregnant women who had normal development of pregnancy. The research is approved by the Ethical committee of the Mostar University Hospital Center, and it was made in accordance with Helsinki declaration and good clinical practices. The research conducted section for pathology of pregnancy of Department for gynecology and obstetrics of the Mostar University Hospital Center. It included 82 pregnant women with disorders in pregnancy developement and control group consisted of pregnant women who had normal development of pregnancy. The research work was conducted from September 2007 to August 2008 in Mostar University Hospital Center. Pregnant women had Standard and laboratory tests, Ultrasound. CTG examinations were done for all pregnant women and additional tests for those women with complications during pregnancy. Pregnant women completed sociobiographical, obstetrical-clinical and psychological SCL 90-R questionnaire. Pregnant women with pathological pregnancy exibited significantly more psychological symptoms in comparison to pregnant women with normal pregnancy (p < 0.001 to p = 0.004). Frequency and intensity of psychical symptoms and disorders statisticly are more characteristic in pathological pregnancy (61%/40.6%). The statistical data indicate a significantly higher score of psychological disorders in those pregnant women with primary school education (p = 0.050), those who take more than 60% carbohydrates (p = 0.001), those with pathological CTG records (p < 0.001), those with pathological ultrasound results (p < 0.001 to 0.216) and those pregnant women with medium obesity and obesity (p = 0.046). Body mass index (BMI) during normal pregnancy development is lower (p = 0.002) but the levels of glucose, triglycerides, cholesterol, HDL and LDL in blood are higher Blood pressure in pregnant women with pathological pregnancy was statistically significantly higher (p < 0.001). Diagnostic criteria for the metabolic syndrome were found in 19 pregnant women with the pathological pregnancy. Statistically, in those women, a significantly higher appearance of psychological symptoms and disorders was observed in comparison to the pregnant women without metabolic syndrome (p < 0.001). The research has shown that 87.8% from all pregnant women included in this study have been hospitalized due to premature birth, hypertensive disorders, and diabetes in pregnancy, and also due to bleeding in the second and third trimester of pregnancy

Relationship between serum lipid concentrations and posttraumatic stress disorder symptoms in soldiers with combat experiences.

The aim of our study was to assess concentrations of serum cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglycerides in soldiers with combat-related posttraumatic stress disorder (PTSD), in comparison with combat-experienced soldiers without PTSD. The second aim of our study was to explore the relationship between PTSD symptoms such as re-experiencing, avoidance, increased arousal, and serum lipid levels. In 53 soldiers with combat-related PTSD and 49 with combat experiences without PTSD, serum cholesterol, LDL-C, HDL-C, and triglycerides were assayed by an enzyme-assay method. Soldiers with combat-related PTSD were found to have significantly higher concentrations of cholesterol (P = 0.001), LDL-C (P = 0.002), and triglycerides (P = 0.001) than soldiers without current PTSD. HDL-C was statistically lower (P &#60; 0.001) in soldiers with combat-related PTSD than in those without PTSD. A positive correlation was found between increased arousal and cholesterol (r = 0.464; P = 0.039), or LDL-C (r = 0.479; P = 0.021) concentrations.</p

ASSOCIATION BETWEEN RESILIENCE AND QUALITY OF LIFE IN PATIENTS WITH COLON CANCER

Introduction: Colon cancer is one of the most common malignancies. Numerous studies suggest an association between resilience and quality of life in colon cancer patients. The aim of this study was to explore the association between resilience and quality of life in people with colon cancer. Subjects and methods: A cross-sectional study was conducted on a sample of 200 subjects at the Oncology Clinic of the University Clinical Hospital Mostar. Data were collected in the period between April 2019 and June 2021. A socio-demographic questionnaire specifically designed for this study, a CD-RISC-25 scale for assessing resilience, and a WHOQOL-BREF questionnaire for assessing quality of life were used for collecting data. Results: A statistically significant positive association of resilience with all domains of quality of life was found. The mental health domain contributed the most statistically significantly positively to the level of resilience. Patients who were not married had a statistically significantly higher level of resilience compared to married, divorced and widowed patients. No statistically significant difference was found in resilience levels relative to other socio-demographic factors and cancer stage. Patients treated with a combination of surgery and chemotherapy had a statistically significantly higher level of resilience compared to patients treated with other therapeutic methods. Conclusions: Higher level of resilience statistically significantly contributes to a higher level of quality of life in people with colon cancer

ASSOCIATION BETWEEN RESILIENCE AND QUALITY OF LIFE IN PATIENTS WITH COLON CANCER

Introduction: Colon cancer is one of the most common malignancies. Numerous studies suggest an association between resilience and quality of life in colon cancer patients. The aim of this study was to explore the association between resilience and quality of life in people with colon cancer. Subjects and methods: A cross-sectional study was conducted on a sample of 200 subjects at the Oncology Clinic of the University Clinical Hospital Mostar. Data were collected in the period between April 2019 and June 2021. A socio-demographic questionnaire specifically designed for this study, a CD-RISC-25 scale for assessing resilience, and a WHOQOL-BREF questionnaire for assessing quality of life were used for collecting data. Results: A statistically significant positive association of resilience with all domains of quality of life was found. The mental health domain contributed the most statistically significantly positively to the level of resilience. Patients who were not married had a statistically significantly higher level of resilience compared to married, divorced and widowed patients. No statistically significant difference was found in resilience levels relative to other socio-demographic factors and cancer stage. Patients treated with a combination of surgery and chemotherapy had a statistically significantly higher level of resilience compared to patients treated with other therapeutic methods. Conclusions: Higher level of resilience statistically significantly contributes to a higher level of quality of life in people with colon cancer

THE RELATIONSHIP BETWEEN HEALTH LOCUS OF CONTROL, DEPRESSION, AND SOCIODEMOGRAPHIC FACTORS AND AMOUNT OF TIME BREAST CANCER PATIENTS WAIT BEFORE SEEKING DIAGNOSIS AND TREATMENT

Background: In the Federation of Bosnia and Herzegovina, the prevalence and incidence of breast cancer has been increasing, and the national programme of early prevention, administered locally, is sporadic and without quality assurance. While many factors may influence women\u27s decision to adopt prevention-oriented behaviours regarding breast cancer, this study has emphasised the importance of sociodemographic factors, psychological factors and mental wellbeing. Subjects and methods: Participants in the study were all patients who, during one year, were admitted for the first time for diagnosis and treatment in the biggest Clinical hospitals of the Herzegovina-Neretva region Patients were divided into two groups based on their TNM classification: "early stage" and "late stage". Three instruments were used in this study: an individual questionnaire about demographic and socioeconomic characteristics of the woman, the Multidimensional Health Locus of Control scales, and the Hamilton Depression Rating Scale Results: The majority of patients diagnosed with advanced disease were admitted to hospital in the late/advanced stages of the disease. Multi-variant analysis showed that the most statistically significant positive predictor for early admittance in hospital is living with family and marital status while religiosity has a negative predictive value. The results indicate that 59.7% of respondents do not have depression, while the remainder do have some degree of depression. There was no statistically significant difference in the degree of depression between women who were diagnosed and treated early and those who were not. The employment status of the respondents was the only significant factor related to degree of depression. Conclusion: Although health locus of control and depression are not statistically significant predictors of early hospital treatment, the recommendation is that further studies focus on the implementation of MHLC and HDRS scales within the community. This could be useful in planning appropriate and specific interventions, not only because of early diagnosis, but also to ensure good mental health and resilient behaviour

Leukociti i drugi hematološki pokazatelji u hrvatskih ratnih veterana s posttraumatskim stresnim poremećajem

The aim of the study was to assess differences in white blood cell (WBC), neutrophil, monocyte, basophil, eosinophil and lymphocyte counts between Croatian veterans with combat-related posttraumatic stress disorder (PTSD) and those with combat-related PTSD comorbid with major depressive disorder (MDD). PTSD and/or MDD were diagnosed according to a structured clinical interview based on DSM-IV criteria. Additional criteria were Clinician Administered PTSD Scale (CAPS) for PTSD and Montgomery-Asberg Depression Rating Scale (MADRAS) for MDD. WBC was measured on an automatic blood counter. Results showed no statistically significant difference in WBC, neutrophil, lymphocyte, monocyte, eosinophil, basophil and red blood cell counts (RBC), hemoglobin, hematocrit, MCV, MCH, MCHC and platelet count between the veterans with combat-related PTSD, veterans with combat-related PTSD + MDD comorbidity, and patients with MDD only. In conclusion, there were no differences in WBC, neutrophil, lymphocyte, monocyte, eosinophil, basophil and RBC counts, hemoglobin, hematocrit, MCV, MCH, MCHC and platelet count among veterans with combat-related PTSD, veterans with combat-related PTSD comorbid with MDD, and patients with MDD only.Cilj ove studije bio je ispitati razlike u broju leukocita, neutrofila, monocita, bazofila, eozinofila i limfocita u hrvatskih ratnih veterana s post-traumatskim stresnim poremećajem (PTSP) uzrokovanog ratnim traumama u usporedbi s istim poremećajem uz istodobno prisutan velik depresivni poremećaj (VDP). Dijagnoza PTSP i/ili VDP postavljena je pomoću strukturiranog kliničkog upitnika prema kriterijima DSM-IV. Kao dopunski kriteriji primijenjena je Clinician Administered PTSD ljestvica (CAPS) za PTSP te Montgomery-Asberg Depression Rating Scale (MADRAS) za VDP. Broj leukocita izmjeren je na automatskom hemaološkom brojaču. Rezultati nisu pokazali nikakvu statistički značajnu razliku u broju leukocita, neutrofila, limfocita, monocita, eozinofila, bazofila, eritrocita, trombocita, kao ni u razini hemoglobina, hematokrita, MCV, MCH i MCHC između veterana s PTSP uzrokovanog ratnim traumama, veterana s PTSP uzrokovanog ratnim traumama i istodobnim VDP i bolesnika koji boluju samo od VDP. Zaključuje se kako ne postoje razlike u broju leukocita, neutrofila, limfocita, monocita, eozinofila, bazofila, eritrocita, trombocita, kao ni u razini hemoglobina, hematokrita, MCV, MCH i MCHC između veterana s PTSP uzrokovanog ratnim traumama, veterana s PTSP uzrokovanog ratnim traumama i istodobnim VDP i bolesnika koji boluju samo od VDP

Serumski lipidi u bolesnika s posttraumatskim stresnim poremećajem, paničnim poremećajem ili generaliziranim anksioznim poremećajem

The aim of the study was to assess the possible differences in serum cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides among patients with post-traumatic stress disorder, panic disorder or generalized anxiety disorder. The post-traumatic stress disorder, panic disorder or generalized anxiety disorder were diagnosed according to structured clinical interview based on DSM-IV criteria. Serum lipid concentrations were determined by use of enzyme assay. Patients with post-traumatic stress disorder and those with panic disorder had significantly higher concentrations of cholesterol (F=5.091, p<0.009), triglycerides (F=4.175, p<0.02) and LDL-C (F=4.973, p<0.001) than patients with generalized anxiety disorder. In contrast, patients with generalized anxiety disorder showed significantly higher concentrations of HDL-C (F=4.244, p<0.019) than those with post-traumatic stress disorder or panic disorder. In conclusion, there were no differences in serum lipid concentrations between patients with post-traumatic stress disorder and panic disorder, but they had higher serum lipid concentrations than patients with generalized anxiety disorder.Cilj rada bio je ispitati moguće razlike u serumskim koncentracijama kolesterola, kolesterola niske gustoće (LDL-C), kolesterola visoke gustoće (HDL-C) i triglicerida između bolesnika s posttraumatskim stresnim poremećajem, paničnim poremećajem i generaliziranim anksioznim poremećajem. Posttraumatski stresni poremećaj, panični poremećaj ili generalizirani anksiozni poremećaj dijagnosticirani su pomoću strukturiranog kliničkog intervjua zasnovanog na kriterijima DSM-IV. Razina serumskih lipida analizirana je enzimskom metodom. Bolesnici s posttraumatskim stresnim poremećajem i oni s paničnim poremećajem imali su značajno više koncentracije kolesterola (F=5,091, p<0,009), triglicerida (F=4,175, p<0,02) i LDL-C (F=4,973, p<0,001) nego bolesnici s generaliziranim anksioznim poremećajem. Suprotno tome, bolesnici s generaliziranim anksioznim poremećajem imali su značajno višu koncentraciju HDL-C (F=4,244, p<0,019) u usporedbi s bolesnicima s posttraumatskim stresnim poremećajem ili paničnim poremećajem. Dakle, nije bilo razlike u serumskoj koncentraciji lipida između bolesnika s posttraumatskim stresnim poremećajem i paničnim poremećajem, ali su imali više razine kolesterola, triglicerida i LDL-C nego bolesnici s generaliziranim anksioznim poremećajem