Sestre Milosrdnice University hospital and Institute of Clinical Medical Research
Abstract
The aim of the study was to assess differences in white blood cell (WBC), neutrophil, monocyte, basophil, eosinophil and lymphocyte counts between Croatian veterans with combat-related posttraumatic stress disorder (PTSD) and those with combat-related PTSD comorbid with major depressive disorder (MDD). PTSD and/or MDD were diagnosed according to a structured clinical interview based on DSM-IV criteria. Additional criteria were Clinician Administered PTSD Scale (CAPS) for PTSD and Montgomery-Asberg Depression Rating Scale (MADRAS) for MDD. WBC was measured on an automatic blood counter. Results showed no statistically significant difference in WBC, neutrophil, lymphocyte, monocyte, eosinophil, basophil and red blood cell counts (RBC), hemoglobin, hematocrit, MCV, MCH, MCHC and platelet count between the veterans with combat-related PTSD, veterans with combat-related PTSD + MDD comorbidity, and patients with MDD only. In conclusion, there were no differences in WBC, neutrophil, lymphocyte, monocyte, eosinophil, basophil and RBC counts, hemoglobin, hematocrit, MCV, MCH, MCHC and platelet count among veterans with combat-related PTSD, veterans with combat-related PTSD comorbid with MDD, and patients with MDD only.Cilj ove studije bio je ispitati razlike u broju leukocita, neutrofila, monocita, bazofila, eozinofila i limfocita u hrvatskih ratnih veterana s post-traumatskim stresnim poremećajem (PTSP) uzrokovanog ratnim traumama u usporedbi s istim poremećajem uz istodobno prisutan velik depresivni poremećaj (VDP). Dijagnoza PTSP i/ili VDP postavljena je pomoću strukturiranog kliničkog upitnika prema kriterijima DSM-IV. Kao dopunski kriteriji primijenjena je Clinician Administered PTSD ljestvica (CAPS) za PTSP te Montgomery-Asberg Depression Rating Scale (MADRAS) za VDP. Broj leukocita izmjeren je na automatskom hemaološkom brojaču. Rezultati nisu pokazali nikakvu statistički značajnu razliku u broju leukocita, neutrofila, limfocita, monocita, eozinofila, bazofila, eritrocita, trombocita, kao ni u razini hemoglobina, hematokrita, MCV, MCH i MCHC između veterana s PTSP uzrokovanog ratnim traumama, veterana s PTSP uzrokovanog ratnim traumama i istodobnim VDP i bolesnika koji boluju samo od VDP. Zaključuje se kako ne postoje razlike u broju leukocita, neutrofila, limfocita, monocita, eozinofila, bazofila, eritrocita, trombocita, kao ni u razini hemoglobina, hematokrita, MCV, MCH i MCHC između veterana s PTSP uzrokovanog ratnim traumama, veterana s PTSP uzrokovanog ratnim traumama i istodobnim VDP i bolesnika koji boluju samo od VDP
