4,992 research outputs found

    Guided Open Vocabulary Image Captioning with Constrained Beam Search

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    Existing image captioning models do not generalize well to out-of-domain images containing novel scenes or objects. This limitation severely hinders the use of these models in real world applications dealing with images in the wild. We address this problem using a flexible approach that enables existing deep captioning architectures to take advantage of image taggers at test time, without re-training. Our method uses constrained beam search to force the inclusion of selected tag words in the output, and fixed, pretrained word embeddings to facilitate vocabulary expansion to previously unseen tag words. Using this approach we achieve state of the art results for out-of-domain captioning on MSCOCO (and improved results for in-domain captioning). Perhaps surprisingly, our results significantly outperform approaches that incorporate the same tag predictions into the learning algorithm. We also show that we can significantly improve the quality of generated ImageNet captions by leveraging ground-truth labels.Comment: EMNLP 201

    Transcutaneous electrical nerve stimulation for cancer pain in adults.

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    Background Cancer-related pain is complex and multi-dimensional but the mainstay of cancer pain management has predominately used a biomedical approach. There is a need for non-pharmacological and innovative approaches. Transcutaneous Electric Nerve Stimulation (TENS) may have a role for a significant number of patients but the effectiveness of TENS is currently unknown. Objectives The aim of this systematic review was to determine the effectiveness of TENS for cancer-related pain in adults. Search strategy We searched The Cochrane Library, MEDLINE, EMBASE, CINAHL, PsychINFO, AMED and PEDRO databases (11/04/08). Selection criteria Only randomised controlled trials (RCTS) investigating the use of TENS for the management of cancer-related pain in adults were included. Data collection and analysis The search strategy identified 37 possible published studies which were divided between two pairs of review authors that decided on study selection. A study eligibility form was used to screen each abstract and where study eligibility could not be determined from the abstract, the full paper was obtained and assessed by one pair of review authors. A standardised data extraction sheet was used to collect information on the studies and the quality of the studies was assessed independently by two review authors using the validated five-point Oxford Quality Scale. Final scores were discussed and agreed between all four review authors. The small sample sizes and differences in patient study populations of the two included studies prevented meta-analysis. Main results Only two RCTs met the eligibility criteria (64 participants). These studies were heterogenous with respect to study population, sample size, study design, methodological quality, mode of TENS, treatment duration, method of administration and outcome measures used. In one RCT, there were no significant differences between TENS and placebo in women with chronic pain secondary to breast cancer treatment. In the other RCT, there were no significant differences between acupuncture-type TENS and sham in palliative care patients; this study was underpowered. Authors' conclusions The results of this systematic review are inconclusive due to a lack of suitable RCTs. Large multi-centre RCTs are required to assess the value of TENS in the management of cancer-related pain in adults

    Cdc53p acts in concert with Cdc4p and Cdc34p to control the G1 to S phase transition and identifies a conserved family of proteins

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    Regulation of cell cycle progression occurs in part through the targeted degradation of both activating and inhibitory subunits of the cyclin-dependent kinases. During G1, CDC4, encoding a WD-40 repeat protein, and CDC34, encoding a ubiquitin-conjugating enzyme, are involved in the destruction of these regulators. Here we describe evidence indicating that CDC53 also is involved in this process. Mutations in CDC53 cause a phenotype indistinguishable from those of cdc4 and cdc34 mutations, numerous genetic interactions are seen between these genes, and the encoded proteins are found physically associated in vivo. Cdc53p defines a large family of proteins found in yeasts, nematodes, and humans whose molecular functions are uncharacterized. These results suggest a role for this family of proteins in regulating cell cycle proliferation through protein degradation

    Project Management Courses in IS Graduate Programs: What is Being Taught?

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    The most recent model curriculum for graduate information systems programs includes a project management course, which contains a balance of technical and managerially related skills. Prior research has shown that adoption of this project management course among information systems graduate programs is not extensive. This study compares the topical coverage of the courses that are being offered against the Project Management lnstitute\u27s Project Management Body of Knowledge (PMBOK) and Georgia State University\u27s Computer Information Systems graduate project management course in information technology. A web-based survey of 206 institutions with graduate information systems programs was conducted; 103 responded and 78 indicated that they had a project management course with 41 instructors completing the questionnaire (53% response rate). Data collected from the survey were then analyzed using descriptive statistics. With respect to the topics of project management found in the PMBOK, information systems programs are covering hard skills such as project scope and cost management to a large extent and giving less emphasis to soft skills such as human resource and project communications management. Also, procurement management is only covered to a very small extent. Similarly, information systems programs matched well with the benchmark course at Georgia State University in the extent of coverage for hard skills such as work breakdown, estimation, and project networks, but their coverage of areas such as project chartering and dealing with vendors and suppliers was considerably lower

    Equi-Biaxial Fatigue Behaviour of Magnetorheological Elastomers in Magnetic Fields

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    The equi-biaxial fatigue behaviour of silicone based magnetorheological elastomers (MREs) in external magnetic fields was studied. Wöhler curves relating fatigue life to stress amplitude and dynamic stored energy for MREs with a range of magnetic particle contents were derived. It was found that the fatigue life of MREs in magnetic fields was higher than that without magnetic fields. Under constant stress amplitude conditions, the presence of magnetic fields resulted in longer times for the samples to undergo large deformations and thus complex modulus (E*) decreased at a slower rate during the fatigue process, especially for low stress amplitudes. MRE samples tested in the presence of magnetic fields reached limiting values of E* at failure ranging from 1.28 MPa to 1.44 MPa. The application of magnetic fields was found to have negligible influence on the damping loss factor of MREs containing various volume fractions of carbonyl iron particles

    Equi-biaxial fatigue testing of EPM utilising bubble inflation

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    This paper describes an equi-biaxial tension fatigue test system which utilises the bubble inflation method to subject elastomers to equi-biaxial fatigue loading between user-defined limits of pressure, volume, stretch ratio or stress. The test system integrates a hydraulic inflation system, a high speed vision system and a control system. The high-speed vision system allows the stretch ratio and stress acting on the test specimen to be evaluated in real-time during testing. This in turn allows either stretch ratio or stress to be used as a direct control limit. In this research, constant maximum engineering stress control tests have been carried out to evaluate the suitability of the developed dynamic bubble inflation system for equi-biaxial fatigue testing of elastomers. The resulting test data was used to produce Wöhler (S/N) curves and stress/stretch ratio plots for ethylene-propylene rubber (EPM)

    Vision-and-Language Navigation: Interpreting visually-grounded navigation instructions in real environments

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    A robot that can carry out a natural-language instruction has been a dream since before the Jetsons cartoon series imagined a life of leisure mediated by a fleet of attentive robot helpers. It is a dream that remains stubbornly distant. However, recent advances in vision and language methods have made incredible progress in closely related areas. This is significant because a robot interpreting a natural-language navigation instruction on the basis of what it sees is carrying out a vision and language process that is similar to Visual Question Answering. Both tasks can be interpreted as visually grounded sequence-to-sequence translation problems, and many of the same methods are applicable. To enable and encourage the application of vision and language methods to the problem of interpreting visually-grounded navigation instructions, we present the Matterport3D Simulator -- a large-scale reinforcement learning environment based on real imagery. Using this simulator, which can in future support a range of embodied vision and language tasks, we provide the first benchmark dataset for visually-grounded natural language navigation in real buildings -- the Room-to-Room (R2R) dataset.Comment: CVPR 2018 Spotlight presentatio
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