Baseline subject characteristics across tertiles of baseline sedentary behaviour in males.

<p>Data are expressed as mean (SD) unless otherwise specified.</p><p>L = low sedentary behaviour at baseline; M = medium sedentary behaviour at baseline; H = high sedentary behaviour at baseline; MVPA, moderate-to-vigorous physical activity; BMI, body mass index; AT, adipose tissue; HOMA-IR, homeostasis model assessment of insulin resistance; AUC, area under-the-curve.</p>*<p>In Québec, there is a level of education generally lasting 2 to 3 years between high school and university termed CEGEP (<i>Collège d'Enseignement Général et Professionnel</i>), an acronym that does not have any translation in English.</p

Mean BMI and BMI Z-score by age and weight trajectory group (N = 1566).

<p>Mean BMI and BMI Z-score by age and weight trajectory group (N = 1566).</p

Baseline subject characteristics across tertiles of baseline sedentary behaviour in females.

<p>Data are expressed as mean (SD) unless otherwise specified.</p><p>L = low sedentary behaviour at baseline; M = medium sedentary behaviour at baseline; H = high sedentary behaviour at baseline; MVPA, moderate-to-vigorous physical activity; BMI, body mass index; AT, adipose tissue; HOMA-IR, homeostasis model assessment of insulin resistance; AUC, area under-the-curve.</p>*<p>In Québec, there is a level of education generally lasting 2 to 3 years between high school and university termed CEGEP (<i>Collège d'Enseignement Général et Professionnel</i>), an acronym that does not have any translation in English.</p

Associations (95% confidence interval) of baseline sedentary behaviour with 6-year change in markers of adiposity.

<p>Model 1: unadjusted.</p><p>Model 2: adjusted for age and sex.</p><p>Model 3: adjusted for age, sex, baseline BMI, energy intake, moderate-to-vigorous physical activity, educational level, income, smoking and menopausal status.</p>*<p><i>p</i><0.05.</p><p>M, Male; F, Female; BMI, Body Mass Index; WC, Waist Circumference; Fat%, body fat percentage; TAAT, total abdominal adipose tissue; VAT, visceral adipose tissue; ASAT, abdominal subcutaneous adipose tissue.</p

Associations (95% confidence interval) of sedentary behaviour and markers of cardiometabolic risk at baseline.

<p>Model 1: unadjusted.</p><p>Model 2: adjusted for age and sex.</p><p>Model 3: adjusted for age, sex, BMI, energy intake, moderate-to-vigorous physical activity, educational level, income, smoking and menopausal status.</p>*<p><i>p</i><0.05.</p><p>M, Male; F, Female; HDL-C, HDL-Cholesterol; LDL-C, LDL-Cholesterol; TG, triglycerides; FG, fasting glucose; FI, fasting insulin; AUC, area under-the-curve.</p

Definitions of explanatory variables.

a<p>Time-dependent indicates that these variables were available at 4, 6, 7, 8, and 10 years of age and thus were treated as time-dependent explanatory variables in the analysis. If a variable was only measured once and occurred at or before baseline (4 y) it was treated as a ‘risk factor’ (time-stable).</p>b<p>Missing at 4 y of age for all children, value at age 3.5 y was carried forward to age 4.</p>c<p>For more information on how this variable was calculated and interpreted, please see reference 32.</p>d<p>Measured every other data collection cycle for all children (value at age 6 was carried forward for age 7).</p

Results of unadjusted and multivariable group-based trajectory models estimating the relationship between time-stable explanatory variables and probability of group membership, and change in average group BMI Z-score as a function of time-dependent explanatory variables (QLSCD children from 4–10 y of age).

a<p>Place factors plus social factors, model includes both time-stable (risk factors) and time-dependent explanatory variables.</p>b<p>Model 1, plus adjustment for early life factors; model includes both time-stable (risk factors) and time-dependent explanatory variables.</p>c<p>Odds ratios and 95% confidence intervals from multinomial logistic regression, reference group is the medium-high, slow increasing group.</p>d<p>Parameters represent the average increase/decrease in BMI Z-score per year within each trajectory group based on a polynomial link function.</p>e<p>Reference group is Urban.</p>*<p><i>P≤</i> 0.05, **<i>P ≤</i> 0.01 *** <i>P ≤</i> 0.0001; CI  =  confidence interval; SE  =  standard error.</p

Associations (95% confidence interval) of baseline sedentary behaviour with 6-year change in markers of cardiometabolic risk.

<p>Model 1: unadjusted.</p><p>Model 2: adjusted for age and sex.</p><p>Model 3: adjusted for age, sex, baseline BMI, energy intake, moderate-to-vigorous physical activity, educational level, income, smoking and menopausal status.</p>*<p><i>p</i><0.05.</p><p>M, Male; F, Female; HDL-C, HDL-Cholesterol; LDL-C, LDL-Cholesterol; TG, triglycerides; FG, fasting glucose; FI, fasting insulin; AUC, area under-the-curve.</p

Associations (95% confidence interval) of sedentary behaviour and markers of adiposity at baseline.

<p>Model 1: unadjusted.</p><p>Model 2: adjusted for age and sex.</p><p>Model 3: adjusted for age, sex, BMI, energy intake, moderate-to-vigorous physical activity, educational level, income, smoking and menopausal status.</p>*<p><i>p</i><0.05.</p><p>M, Male; F, Female; BMI, Body Mass Index; WC, Waist Circumference; Fat%, body fat percentage; TAAT, total abdominal adipose tissue; VAT, visceral adipose tissue; ASAT, abdominal subcutaneous adipose tissue.</p

Estimated weight change trajectories and 95% confidence intervals in the QLSCD from 4–10 y of age (n = 1566).

<p>Estimated weight change trajectories and 95% confidence intervals in the QLSCD from 4–10 y of age (n = 1566).</p